The Best Business Hotels in South San Diego, CA from SAR 300 in 2025

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Compare South San Diego Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Daily continental breakfast (USD 13.49 per person)

"Always a great trip. The staff is always helpful and kind. The area is perfect for walking to many restaurants. They continue to keep the rooms in good condition and take care of the property. Very secure. You must enter through the lobby. "

SAR 445 total

includes taxes & fees

16 Mar - 17 Mar

"Beds are so comfortable "

SAR 537 total

includes taxes & fees

23 Mar - 24 Mar

"Clean, comfortable rooms. Nice hot tub. Excellent breakfast, including eggs when other comfort ends are not offering eggs. I plan to stay another night due to the great experience of first night."

SAR 436 total

includes taxes & fees

9 Mar - 10 Mar

"Staff was amazing, rooms super clean and tidy"

SAR 452 total

includes taxes & fees

9 Mar - 10 Mar

"Easy check in late at night"

SAR 442 total

includes taxes & fees

23 Mar - 24 Mar

Deluxe Double Room, Ensuite (QUEEN W/ FRIG)

"Not your traditional hotel, no full time person at desk, no breakfast or anything such as that. Did see some coffee and hot chocolate packs, but that was all, but plenty of places to eat within walking distance. Hotel was clean, rooms on the small size. We got a King size room and was not a traditional size room. Overall it was great for us as we had an event nearby. 7-11 Across the street if you need to buy snack or drinks. "

SAR 353 total

includes taxes & fees

2 Mar - 3 Mar

Studio Suite, King Bed with Sofa bed, Accessible, Non Smoking (Mobility Accessible) | Pillowtop beds, desk, blackout drapes, iron/ironing board

"Good "

SAR 701 total

includes taxes & fees

2 Mar - 3 Mar

Pillowtop beds, in-room safe, desk, laptop workspace

"It is a clean hotel."

SAR 499 total

includes taxes & fees

16 Mar - 17 Mar

Find out more about South San Diego

Recent reviews of South San Diego hotels

5/5 Excellent

"The price was very reasonable for San Diego. The staff at the front desk and the maids were extremely courteous and helpful. The location was convenient and although safe, not the best part of town. The room was very clean. The mattress was new and firm. Stayed for nine days in February 2025. Complimentary breakfast (while the room was being renovated) consisted of brown bags for each guest containing orange juice, banana or orange, yogurt, Jimmy Dean sausage sandwich, pastry, bottle of water and protein bar. Not the del Coronado hotel but would definitely stay there again."