Photo by Michele Butts

Find Luxury Hotels in La Mesa, CA

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Check availability on La Mesa Luxury Hotels

Compare La Mesa Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1001)
"Me encanto el hotel, super tranquilo!!. Todo limpio. Super atentos todos."
The price is SAR 443
SAR 488 total
includes taxes & fees
20 Apr - 21 Apr
Best Western Plus La Mesa San Diego

Motel 6 La Mesa, CA

2.0 star property
7.2 out of 10, Good, (1002)
"One of the best motels I’ve stayed at while visiting San Diego! The front desk staff were incredibly friendly and polite, making check-in a breeze. The rooms appeared to be recently remodeled. I also appreciated the convenience of having a mini refrigerator and microwave in the room. Overall, a great stay—I would definitely book this location again! "
The price is SAR 364
SAR 400 total
includes taxes & fees
30 Mar - 31 Mar
Motel 6 La Mesa, CA

Heritage Inn La Mesa

2.0 star property
6.4 out of 10, (1046)
"has a lot of bugs"
The price is SAR 271
SAR 298 total
includes taxes & fees
23 Mar - 24 Mar
Heritage Inn La Mesa

Holiday Inn Express La Mesa Near SDSU by IHG

2.5 star property
8.4 out of 10, Very Good, (271)
"Great location for our needs! Carpet was coming up as it was frayed and a drawer was broken making it unusable! "
The price is SAR 491
SAR 541 total
includes taxes & fees
30 Mar - 31 Mar
Holiday Inn Express La Mesa Near SDSU by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in La Mesa?
Use Expedia and let us help you arrange a flight to San Diego, CA (SEE-Gillespie Field) airport or San Diego, CA (MYF-Montgomery Field) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to get what you want to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that La Mesa has to offer. During your visit, you might want to enjoy the entertainment which La Mesa is known for.
How many luxury hotels can I expect to find in La Mesa?
Lie in the lap of luxury during your getaway to La Mesa in one of Expedia’s 6 luxury hotels.
When can I expect good weather in La Mesa?
Planning for the weather is an important factor for making your trip to La Mesa a success, especially when you’re splurging. The hottest months are usually August and September with an average temp of 72°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for La Mesa is 12 inches.
What's there to see and do in La Mesa?
Enjoy La Mesa with a stop at Mount Helix Park, San Diego Zoo, and Mission Bay. If you have a bit of extra time while you’re in the area, you might want to check out San Ysidro Border Crossing and Petco Park.
How can I get around La Mesa?
It’s easier to get around town in style when you know your options. Nearby metro stations include La Mesa Boulevard Station, Spring St Trolley Station, and 70th St. Trolley Station.