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Find hotels in Sikeston, MO from SAR 251
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Compare 255 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1002)
The price is SAR 354
SAR 400 total
includes taxes & fees
30 Mar - 31 Mar

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
9.4 out of 10, Exceptional, (1000)
The price is SAR 401
SAR 453 total
includes taxes & fees
30 Mar - 31 Mar

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
9.0 out of 10, Wonderful, (516)
The price is SAR 309
SAR 335 total
includes taxes & fees
20 Mar - 21 Mar

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
9.4 out of 10, Exceptional, (1003)
The price is SAR 287
SAR 330 total
includes taxes & fees
23 Mar - 24 Mar

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
9.4 out of 10, Exceptional, (92)
The price is SAR 349
SAR 394 total
includes taxes & fees
23 Mar - 24 Mar

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
8.6 out of 10, Excellent, (398)
The price is SAR 460
SAR 520 total
includes taxes & fees
30 Mar - 31 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Sikeston and related destinations
Explore Sikeston: its food, riverfront, museums, and more!

Photo by Ryan Coleman
Open Photo by Ryan Coleman
Explore the historic buildings and museums of this delightful South Carolina city that’s also known for its nature trails and outdoor pursuits.

Once a Mexican migrant settlement, this Californian town is located on the edge of one of the most important wetland regions in North America.

Photo by Jess. LongestBusRide
Open Photo by Jess. LongestBusRide
Experience romantic Olive Branch: its food, entertainment, live music, and more!
Lima awaits: its university life, food, cathedral, and more!

Photo by throwingsofas
Open Photo by throwingsofas
More cheap stays in Sikeston
More cheap stays in Sikeston

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
The price is SAR 287 per night from Mar 24 to Mar 25
SAR 287
SAR 327 total
includes taxes & fees
24 Mar - 25 Mar
7.2/10 Good! (1,003 reviews)
Hotels in Sikeston with star-rating
Hotels in Sikeston with star-rating

4 Star Hotels
2 properties
Stay near popular Sikeston attractions
Stay near popular Sikeston attractions
The Book Bug
4/5(5 reviews)
Take the family on an outing to The Book Bug during your trip to Miner. While in this relaxing area, you can savor the top-notch restaurants.
Recent reviews of Sikeston hotels
Recent reviews of Sikeston hotels

The Riverview
5/5 Excellent
"The staff was excellent "
A verified traveler stayed at The Riverview
Posted 20 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Stay near popular Sikeston attractions
- Hotels near Boot Heel Golf Club
- Hotels near The Book Bug
- Hotels near Sikeston Depot Museum
- Hotels near Central Park
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Southeast Missouri State University
- Hotels near Riverfront Bridge Park
- Hotels near Riverfront Park
- Hotels near Big Oak Tree State Park
- Hotels near Mound City National Cemetery
- Hotels near Fort Defiance State Park
- Hotels near eDen Spa & Salon
- Hotels near New Madrid Historical Museum
- Hotels near Fort D Historic Site
- Hotels near Stoddard County Civil War Memorial Cemetery
- Hotels near River Ridge Winery
- Hotels near Dexter Welcome Center Depot and Museum
- Hotels near The Heritage House
More Hotel Options in Sikeston
- Adults Only Resorts & Hotels in Sikeston
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- Business Hotels in Sikeston
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- Cheap Hotels in Sikeston
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- Golf Hotels in Sikeston
- Historic Hotels in Sikeston
- Hotel Wedding Venues in Sikeston
- Hotels with Bars in Sikeston
- Hotels with Free Parking in Sikeston
- Hotels with Hot Tubs in Sikeston
- Hotels with WiFi in Sikeston
- Hotels with a Pool in Sikeston
- Hotels with an Indoor Pool in Sikeston
- Hotels with smoking rooms in Sikeston
- Luxury Hotels in Sikeston
- Pet-friendly Hotels in Sikeston
- Resorts & Hotels with Spas in Sikeston
- Romantic Hotels in Sikeston
- Shopping Hotels in Sikeston
- Winery Hotels in Sikeston
Sikeston Hotels by Brand
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Explore more hotels
- The Riverview
- Drury Plaza Hotel Cape Girardeau Conference Center
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Pear Tree Inn Cape Girardeau West
- Candlewood Suites Cape Girardeau by IHG
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Courtyard by Marriott Cape Girardeau Downtown
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Drury Inn & Suites Cape Girardeau
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Quality Inn
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