Photo by Ryan Coleman

Find hotels in Sikeston, MO from SAR 224

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Compare 261 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1009)
"Always a pleasant stay"
The price is SAR 321
SAR 369 total
includes taxes & fees
11 May - 12 May
Pear Tree Inn Sikeston

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1007)
"Friendly staff nice rooms, Breakfast is awesome "
The price is SAR 316
SAR 360 total
includes taxes & fees
1 Jun - 2 Jun
Best Western Plus Sikeston

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1004)
"Wonder stay! Excellent hotel. "
The price is SAR 371
SAR 427 total
includes taxes & fees
11 May - 12 May
Drury Inn & Suites Sikeston, MO

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1002)
"Very accommodating staff"
The price is SAR 303
SAR 345 total
includes taxes & fees
9 May - 10 May
Days Inn and Suites by Wyndham Sikeston

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (343)
"Nice area"
The price is SAR 443
SAR 502 total
includes taxes & fees
11 May - 12 May
Hampton Inn Sikeston

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very Good, (251)
"We were in town for a pit-stop to sleep and the staff was very nice. Comfy beds and nice location"
The price is SAR 316
SAR 360 total
includes taxes & fees
1 Jun - 2 Jun
Comfort Inn & Suites Sikeston I-55

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (404)
"It was ok "
The price is SAR 495
SAR 561 total
includes taxes & fees
18 May - 19 May
Holiday Inn Express & Suites Sikeston Southwest by IHG

Country Yard Inn and Suite

2.0 star property
7.0 out of 10, Good, (87)
"Nice place excellent service "
The price is SAR 241
SAR 287 total
includes taxes & fees
6 May - 7 May
Country Yard Inn and Suite

The Riverview

2.0 star property
9.2 out of 10, Wonderful, (251)
"Wonderful stay "
The price is SAR 401
SAR 453 total
includes taxes & fees
11 May - 12 May
The Riverview

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1011)
"Great stay!!"
The price is SAR 337
SAR 381 total
includes taxes & fees
11 May - 12 May
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1005)
"Great place with great staff."
The price is SAR 337
SAR 357 total
includes taxes & fees
11 May - 12 May
Drury Inn & Suites Jackson MO

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1001)
"Will definitely stay there again!!"
The price is SAR 371
SAR 419 total
includes taxes & fees
11 May - 12 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
6.6 out of 10, (525)
"Amazing "
The price is SAR 224
SAR 256 total
includes taxes & fees
18 May - 19 May
Super 8 by Wyndham Sikeston/Miner Area

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
9.0 out of 10, Wonderful, (547)
"Quiet, clean, cozy, reasonably priced!"
The price is SAR 322
SAR 348 total
includes taxes & fees
1 Jun - 2 Jun
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Nice place, would stay here again "
The price is SAR 270
SAR 305 total
includes taxes & fees
11 May - 12 May
Pear Tree Inn Cape Girardeau West

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (377)
"Customer service is what sets them apart."
The price is SAR 239
SAR 265 total
includes taxes & fees
1 Jun - 2 Jun
Quality Inn Charleston - Sikeston

Tru By Hilton Cape Girardeau

2.5 star property
9.8 out of 10, Exceptional, (11)
"Exceptionally clean and the staff was absolutely wonderful."
The price is SAR 415
SAR 473 total
includes taxes & fees
5 Jun - 6 Jun
Tru By Hilton Cape Girardeau

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (412)
"I love the Hotel check in was a breeze. The staff were friendly ,helpful and pr"
The price is SAR 435
SAR 493 total
includes taxes & fees
18 May - 19 May
Courtyard by Marriott Cape Girardeau Downtown

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (707)
"Great location"
The price is SAR 411
SAR 464 total
includes taxes & fees
18 May - 19 May
Hampton Inn Cape Girardeau I 55 East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Sikeston and related destinations

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Photo by Ryan Coleman
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A frosted malt, fries and a double hamburger from Kewpee Hamburgers.

Of the five remaining Kewpee restaurants, three of them can be found in Lima, OH.

Kewpee hamburgers started in 1923 and this iconic location in downtown Lima opened in 1928.

A Kewpee location in Kalamazoo, MI, near where Wendy's founder Dave Thomas grew up, is said to have inspired him with their square hamburgers and thick shakes.
Photo by throwingsofas
Open Photo by throwingsofas

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best vacation rentals in Sikeston?

Beautiful location in the secluded woods : This vacation home rental outside of Sikeston offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Pear Tree Inn Sikeston is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families. Drury Inn & Suites Sikeston, MO is another good choice for your stay with the kids. Kids of all ages will also enjoy a visit to The Book Bug. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Pear Tree Inn Sikeston is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Drury Inn & Suites Sikeston, MO and Hampton Inn Sikeston are two other good options for your vacation.

What's the best pet-friendly accommodation in Sikeston?

Pear Tree Inn Sikeston is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Drury Inn & Suites Sikeston, MO and Hampton Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What are some accommodations with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. View all hotels with pools in Sikeston.

What's the best place to stay near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Sikeston like?

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.

What are the top places to visit in Sikeston?

Favorite places to visit include Sikeston Depot Museum, Central Park, and The Book Bug. Additionally, you might want to add Boot Heel Golf Club to your itinerary. Check out what more to see and do in Expedia's Sikeston guide.

What's the seasonal weather like in Sikeston?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.