Photo by Ryan Coleman

Find hotels in Sikeston, MO from SAR 251

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Check prices for these dates

Tonight
18 Rab. I - 19 Rab. I
Tomorrow
19 Rab. I - 20 Rab. I
This weekend
21 Rab. I - 23 Rab. I
Next weekend
28 Rab. I - 30 Rab. I

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Compare 255 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1002)
"Enjoyed the friendly and accommodating staff. We arrived in time to enjoy the complimentary evening meal and cocktails; this was our first time at a Drury Inn so the meal and drinks were an unexpected but very welcome surprise."
The price is SAR 354
SAR 400 total
includes taxes & fees
30 Mar - 31 Mar
Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1000)
"The staff members were all very friendly and helpful. My room could not have been better. "
The price is SAR 401
SAR 453 total
includes taxes & fees
30 Mar - 31 Mar
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Property amenity

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

2.5 star property
9.0 out of 10, Wonderful, (516)
"Very large room with large walk-in closet. Will stay again. "
The price is SAR 309
SAR 335 total
includes taxes & fees
20 Mar - 21 Mar
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Pear Tree Inn Sikeston
Lobby

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1003)
"Great"
The price is SAR 287
SAR 330 total
includes taxes & fees
23 Mar - 24 Mar
Pear Tree Inn Sikeston
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (92)
"Easy on/off of hwy 55. The hotel room was clean and spacious. Good breakfast"
The price is SAR 349
SAR 394 total
includes taxes & fees
23 Mar - 24 Mar
Fairfield Inn & Suites by Marriott Cape Girardeau
Holiday Inn Express & Suites Sikeston Southwest by IHG
Exterior

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (398)
"We needed a place to rest for the night. Excellent choice "
The price is SAR 460
SAR 520 total
includes taxes & fees
30 Mar - 31 Mar
Holiday Inn Express & Suites Sikeston Southwest by IHG
The Riverview
Grand Riverview Two Queen Room | Premium bedding, pillowtop beds, in-room safe, desk

The Riverview

3.5 star property
9.2 out of 10, Wonderful, (185)
"The staff was excellent "
The price is SAR 353
SAR 398 total
includes taxes & fees
23 Mar - 24 Mar
The Riverview
Hampton Inn Sikeston
Exterior

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (321)
"The property is easily accessed from the highway. There are many dining choices in the area including Applebees, chinese buffet, and various fast food chains. Room was clean and quiet. "
The price is SAR 411
SAR 466 total
includes taxes & fees
30 Mar - 31 Mar
Hampton Inn Sikeston
Courtyard by Marriott Cape Girardeau Downtown
Lobby

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (403)
"Had a great visit to Cape. Lovely place to stay the night. Convenient to shoppin, food and fun!"
The price is SAR 469
SAR 531 total
includes taxes & fees
30 Mar - 31 Mar
Courtyard by Marriott Cape Girardeau Downtown
Best Western Plus Sikeston
Lobby

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1002)
"Good location. Dated facility. "
The price is SAR 327
SAR 373 total
includes taxes & fees
23 Mar - 24 Mar
Best Western Plus Sikeston
Comfort Inn & Suites Sikeston I-55
Exterior

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very Good, (242)
"Nice hotel with great staff. Room was fine, breakfast could be better but overall a good stay for this area. "
The price is SAR 368
SAR 419 total
includes taxes & fees
24 Mar - 25 Mar
Comfort Inn & Suites Sikeston I-55
Hampton Inn Cape Girardeau I 55 East
Courtyard

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (693)
"family trip to Cape G. This Hampton Inn is right off I-55 and also right off the roads to downtown Cape G. Plenty of places to eat and walk the dogs"
The price is SAR 411
SAR 464 total
includes taxes & fees
30 Mar - 31 Mar
Hampton Inn Cape Girardeau I 55 East
Comfort Suites Jackson-Cape Girardeau
Lobby

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (691)
"Room looked great when we got there. There was a few things that needed attention. I left them a note."
The price is SAR 323
SAR 349 total
includes taxes & fees
20 Mar - 21 Mar
Comfort Suites Jackson-Cape Girardeau
Pear Tree Inn Cape Girardeau Near the Medical Center
Seasonal outdoor pool

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Very friendly staff and especially the ladies with breakfast with my grandsons who are 8 and 4"
The price is SAR 253
SAR 286 total
includes taxes & fees
23 Mar - 24 Mar
Pear Tree Inn Cape Girardeau Near the Medical Center
Candlewood Suites Cape Girardeau by IHG
Exterior

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.2 out of 10, Very Good, (743)
"I liked the kitchens and refrigerator. "
The price is SAR 308
SAR 368 total
includes taxes & fees
23 Mar - 24 Mar
Candlewood Suites Cape Girardeau by IHG
Days Inn and Suites by Wyndham Sikeston
1 bedroom, desk, laptop workspace, blackout drapes

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1001)
"Having the suite, really makes it much more comfortable I would like to see them making the bed as regular as the towell check"
The price is SAR 287
SAR 327 total
includes taxes & fees
24 Mar - 25 Mar
Days Inn and Suites by Wyndham Sikeston
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (909)
"Staff was polite and very helpful and attentive. Will stay here the next time I’m passing through."
The price is SAR 354
SAR 400 total
includes taxes & fees
23 Mar - 24 Mar
Drury Inn & Suites Cape Girardeau
Quality Inn
Lobby

Quality Inn

2.5 star property
7.0 out of 10, Good, (557)
"Clean very nice staff "
The price is SAR 251
SAR 284 total
includes taxes & fees
20 Mar - 21 Mar
Quality Inn
Rockwood Inn
Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi

Rockwood Inn

2.0 star property
9.8 out of 10, Exceptional, (6)
"Had a wonderful stay at the Rockwood Inn and ready booked additional stay. Perfect location to stay at for football games or any other SEMO event! "
The price is SAR 564
SAR 636 total
includes taxes & fees
1 Apr - 2 Apr
Rockwood Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Open Photo by throwingsofas

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best vacation rentals in Sikeston?

Beautiful location in the secluded woods : This vacation home rental outside of Sikeston offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Pear Tree Inn Sikeston is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families. Drury Inn & Suites Sikeston, MO is another good choice for your stay with the kids. Kids of all ages will also enjoy a visit to The Book Bug. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Pear Tree Inn Sikeston is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Drury Inn & Suites Sikeston, MO and Holiday Inn Express & Suites Sikeston Southwest by IHG are two other good options for your vacation.

What's the best pet-friendly accommodation in Sikeston?

Days Inn and Suites by Wyndham Sikeston is a top hotel for people traveling with their pets, and offers a fitness center and free WiFi for its human guests. Other good options for you and your pet's trip include Pear Tree Inn Sikeston and Drury Inn & Suites Sikeston, MO. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What are some accommodations with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. View all hotels with pools in Sikeston.

What's the best place to stay near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Sikeston like?

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.

What are the top places to visit in Sikeston?

Favorite places to visit include Sikeston Depot Museum, Central Park, and Boot Heel Golf Club. Additionally, you might want to add The Book Bug to your itinerary. Check out what more to see and do in Expedia's Sikeston guide.

What's the seasonal weather like in Sikeston?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.