Photo by Ryan Coleman

Find hotels in Sikeston, MO from SAR 236

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Compare 253 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1000)
"The staff! Everyone was so nice. They all seemed to love their job and were very helpful. The room was clean, quiet and spacious. We booked a room there again on a return trip. "
The price is SAR 371
SAR 419 total
includes taxes & fees
23 Feb - 24 Feb
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (688)
"easy to find"
The price is SAR 411
SAR 464 total
includes taxes & fees
23 Feb - 24 Feb
Hampton Inn Cape Girardeau I 55 East

The Riverview

3.5 star property
9.2 out of 10, Wonderful, (149)
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The price is SAR 364
SAR 410 total
includes taxes & fees
17 Feb - 18 Feb
The Riverview

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (393)
"Would recommend to everyone "
The price is SAR 460
SAR 520 total
includes taxes & fees
23 Feb - 24 Feb
Holiday Inn Express & Suites Sikeston Southwest by IHG

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (396)
" The hotel is excellent!! They done a wonderful job redoing the old buildings into a stunning hotel!! Highly recommend this hotel. "
The price is SAR 443
SAR 502 total
includes taxes & fees
23 Feb - 24 Feb
Courtyard by Marriott Cape Girardeau Downtown

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

2.5 star property
9.0 out of 10, Wonderful, (506)
"Friendly staff and clean. No noise room comfortable."
The price is SAR 306
SAR 331 total
includes taxes & fees
23 Feb - 24 Feb
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1003)
"Perfect location, love the evening and breakfast meals along with the 3 free drinks "
The price is SAR 371
SAR 427 total
includes taxes & fees
24 Feb - 25 Feb
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (888)
"Everyone was so nice and helpful at this hotel! The rooms were clean, spacious, and up to date. Will highly likely stay and recommend this hotel line!"
The price is SAR 354
SAR 400 total
includes taxes & fees
23 Feb - 24 Feb
Drury Inn & Suites Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1003)
"The staff have great customer service and very welcoming. "
The price is SAR 371
SAR 419 total
includes taxes & fees
20 Feb - 21 Feb
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1003)
"Nice place. Very friendly staff. Will stay there again!"
The price is SAR 338
SAR 357 total
includes taxes & fees
23 Feb - 24 Feb
Drury Inn & Suites Jackson MO

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very Good, (234)
"Nice spacious rooms. Beds were very comfortable. Quiet place."
The price is SAR 334
SAR 381 total
includes taxes & fees
23 Feb - 24 Feb
Comfort Inn & Suites Sikeston I-55

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1007)
"Great place to stay "
The price is SAR 287
SAR 330 total
includes taxes & fees
20 Feb - 21 Feb
Pear Tree Inn Sikeston

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1003)
"Great room. I had my lab with me and they put me close to the exit door but not right next to it. They had a dog area. Great outdoor lighting. Smoking area. Great staff. Got breakfast. "
The price is SAR 304
SAR 346 total
includes taxes & fees
27 Feb - 28 Feb
Best Western Plus Sikeston

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (314)
"We were only there for one night but it was so nice and clean!!"
The price is SAR 411
SAR 466 total
includes taxes & fees
23 Feb - 24 Feb
Hampton Inn Sikeston

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (79)
"Excellent stay, very clean! Please add nightlights to the bathrooms"
The price is SAR 348
SAR 392 total
includes taxes & fees
23 Feb - 24 Feb
Fairfield Inn & Suites by Marriott Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (682)
"It was clean and quiet. We were in town for a youth sports event. Breakfast was adequate. Staff was friendly. The hotel and location felt safe."
The price is SAR 342
SAR 370 total
includes taxes & fees
23 Feb - 24 Feb
Comfort Suites Jackson-Cape Girardeau

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1005)
"Nice quiet, safe hotel"
The price is SAR 236
SAR 267 total
includes taxes & fees
23 Feb - 24 Feb
Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.2 out of 10, Very Good, (729)
"Good location. Restaurants close by. Nice clean room."
The price is SAR 293
SAR 351 total
includes taxes & fees
16 Mar - 17 Mar
Candlewood Suites Cape Girardeau by IHG

Rockwood Inn

2.0 star property
9.8 out of 10, Exceptional, (6)
"Had a wonderful stay at the Rockwood Inn and ready booked additional stay. Perfect location to stay at for football games or any other SEMO event! "
The price is SAR 564
SAR 636 total
includes taxes & fees
2 Mar - 3 Mar
Rockwood Inn

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1002)
"Great room"
The price is SAR 239
SAR 273 total
includes taxes & fees
18 Feb - 19 Feb
Days Inn and Suites by Wyndham Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Sikeston and related destinations

Explore Sikeston: its food, riverfront, university life, and more!

The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

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Great food! Big burritos, delicious tacos. Outdoor seating only.
Photo by Jess. LongestBusRide
Open Photo by Jess. LongestBusRide

Experience romantic Olive Branch: its food, entertainment, hockey, and more!

Lima awaits: its university life, food, lake views, and more!

A frosted malt, fries and a double hamburger from Kewpee Hamburgers.

Of the five remaining Kewpee restaurants, three of them can be found in Lima, OH.

Kewpee hamburgers started in 1923 and this iconic location in downtown Lima opened in 1928.

A Kewpee location in Kalamazoo, MI, near where Wendy's founder Dave Thomas grew up, is said to have inspired him with their square hamburgers and thick shakes.
Photo by throwingsofas
Open Photo by throwingsofas

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best vacation rentals in Sikeston?

Notting Hill Cottage: This vacation home rental outside of Sikeston offers a patio, a private yard, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a hot tub. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Pear Tree Inn Sikeston is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families. Drury Inn & Suites Sikeston, MO is another good choice for your stay with the kids. Kids of all ages will also enjoy a visit to The Book Bug. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Pear Tree Inn Sikeston is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Drury Inn & Suites Sikeston, MO and Holiday Inn Express & Suites Sikeston Southwest by IHG are two other good options for your vacation.

What's the best pet-friendly accommodation in Sikeston?

Days Inn and Suites by Wyndham Sikeston is a top hotel for people traveling with their pets, and offers a fitness center and free WiFi for its human guests. Other good options for you and your pet's trip include Pear Tree Inn Sikeston and Drury Inn & Suites Sikeston, MO. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What are some accommodations with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast, and free parking. View all hotels with pools in Sikeston.

What's the best place to stay near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Sikeston like?

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodations to choose from. Find out more about Sikeston.

What are the top places to visit in Sikeston?

Favorite places to visit include The Book Bug, Sikeston Depot Museum, and Boot Heel Golf Club. Additionally, you might want to add Central Park to your itinerary. Check out what more to see and do in Expedia's Sikeston guide.

What's the seasonal weather like in Sikeston?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.