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Find Resorts & Hotels with Spas in Sikeston, MO
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Compare Sikeston Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
9.4 out of 10, Exceptional, (1003)
The price is SAR 287
SAR 330 total
includes taxes & fees
23 Mar - 24 Mar

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
8.4 out of 10, Very Good, (640)
The price is SAR 242
SAR 276 total
includes taxes & fees
20 Mar - 21 Mar

Hampton Inn Sikeston
Hampton Inn Sikeston
8.8 out of 10, Excellent, (321)
The price is SAR 411
SAR 466 total
includes taxes & fees
30 Mar - 31 Mar

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
9.4 out of 10, Exceptional, (1001)
The price is SAR 371
SAR 427 total
includes taxes & fees
6 Apr - 7 Apr

Best Western Plus Sikeston
Best Western Plus Sikeston
8.4 out of 10, Very Good, (1002)
The price is SAR 327
SAR 373 total
includes taxes & fees
23 Mar - 24 Mar

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
7.2 out of 10, Good, (1001)
The price is SAR 287
SAR 327 total
includes taxes & fees
23 Mar - 24 Mar

Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
8.4 out of 10, Very Good, (242)
The price is SAR 368
SAR 419 total
includes taxes & fees
6 Apr - 7 Apr

Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area
6.6 out of 10, (521)
The price is SAR 253
SAR 289 total
includes taxes & fees
23 Mar - 24 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Sikeston
Find out more about Sikeston
Recent reviews of Sikeston hotels
Recent reviews of Sikeston hotels

Drury Plaza Hotel Cape Girardeau Conference Center
5/5 Excellent
"Enjoyed the friendly and accommodating staff.
We arrived in time to enjoy the complimentary evening meal and cocktails; this was our first time at a Drury Inn so the meal and drinks were an unexpected but very welcome surprise."
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Posted 6 days ago
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Hotels near popular Sikeston Attractions
- Hotels near Boot Heel Golf Club
- Hotels near The Book Bug
- Hotels near Sikeston Depot Museum
- Hotels near Central Park
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Southeast Missouri State University
- Hotels near Riverfront Bridge Park
- Hotels near Riverfront Park
Sikeston Hotels by Star Rating
Explore more hotels
- The Riverview
- Drury Plaza Hotel Cape Girardeau Conference Center
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Pear Tree Inn Cape Girardeau West
- Candlewood Suites Cape Girardeau by IHG
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Courtyard by Marriott Cape Girardeau Downtown
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Drury Inn & Suites Cape Girardeau
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Quality Inn
- Drury Inn & Suites Jackson MO
- Holiday Inn Express & Suites Perryville by IHG
- Rest, Relax and Renew. Our log cabin experience awaits your arrival.
- Beautiful location in the secluded woods
- New cabin in the woods with private hot tub
- Town House Inn Cape Giradreau
- Hampton Inn Cape Girardeau I 55 East
- Super 8 by Wyndham Perryville