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Find Resorts & Hotels with Spas in Sikeston, MO
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Compare Sikeston Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
9.4 out of 10, Exceptional, (1016)
The price is SAR 321
SAR 369 total
includes taxes & fees
30 Mar - 31 Mar

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
8.4 out of 10, Very Good, (640)
The price is SAR 246
SAR 280 total
includes taxes & fees
24 Mar - 25 Mar

Hampton Inn Sikeston
Hampton Inn Sikeston
8.8 out of 10, Excellent, (323)
The price is SAR 411
SAR 466 total
includes taxes & fees
30 Mar - 31 Mar

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
9.4 out of 10, Exceptional, (1005)
The price is SAR 371
SAR 427 total
includes taxes & fees
30 Mar - 31 Mar

Best Western Plus Sikeston
Best Western Plus Sikeston
8.4 out of 10, Very Good, (1003)
The price is SAR 340
SAR 388 total
includes taxes & fees
6 Apr - 7 Apr

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
7.2 out of 10, Good, (1003)
The price is SAR 287
SAR 327 total
includes taxes & fees
30 Mar - 31 Mar

Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
8.4 out of 10, Very Good, (245)
The price is SAR 348
SAR 396 total
includes taxes & fees
30 Mar - 31 Mar

Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area
6.6 out of 10, (521)
The price is SAR 267
SAR 305 total
includes taxes & fees
20 Apr - 21 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Sikeston
Find out more about Sikeston
Recent reviews of Sikeston hotels
Recent reviews of Sikeston hotels

Drury Plaza Hotel Cape Girardeau Conference Center
5/5 Excellent
"The Drury was excellent. The room was sapcious and very clean. Breakfast in the morning was great. Easy access to the interstate."
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Posted 2 days ago
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Hotels near popular Sikeston Attractions
- Hotels near The Book Bug
- Hotels near Boot Heel Golf Club
- Hotels near Sikeston Depot Museum
- Hotels near Central Park
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
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- Hotels near Riverfront Bridge Park
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Sikeston Hotels by Star Rating
Explore more hotels
- The Riverview
- Drury Plaza Hotel Cape Girardeau Conference Center
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Pear Tree Inn Cape Girardeau West
- Candlewood Suites Cape Girardeau by IHG
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Drury Inn & Suites Cape Girardeau
- Courtyard by Marriott Cape Girardeau Downtown
- Drury Inn & Suites Jackson MO
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Quality Inn
- Holiday Inn Express & Suites Perryville by IHG
- Town House Inn Cape Giradreau
- Super 8 by Wyndham Perryville
- Rest, Relax and Renew. Our log cabin experience awaits your arrival.
- Days Inn by Wyndham Perryville
- Beautiful location in the secluded woods
- Hampton Inn Cape Girardeau I 55 East