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Compare 546 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

The Riverview
The Riverview
9.2 out of 10, Wonderful, (168)
The price is SAR 361
SAR 407 total
includes taxes & fees
18 Mar - 19 Mar

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1006)
The price is SAR 371
SAR 419 total
includes taxes & fees
9 Mar - 10 Mar

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
9.4 out of 10, Exceptional, (1005)
The price is SAR 371
SAR 419 total
includes taxes & fees
16 Mar - 17 Mar

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
9.4 out of 10, Exceptional, (85)
The price is SAR 349
SAR 393 total
includes taxes & fees
3 Apr - 4 Apr

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff
9.4 out of 10, Exceptional, (695)
The price is SAR 379
SAR 428 total
includes taxes & fees
6 Mar - 7 Mar

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
9.6 out of 10, Exceptional, (399)
The price is SAR 469
SAR 531 total
includes taxes & fees
16 Mar - 17 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Southeast Missouri, MO
Showing deals for:Mar 14 - Mar 16
Image gallery for La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
9.0/10Wonderful (510 reviews)
10% off
Price is SAR 635
per night
SAR 1,374 total
includes taxes & fees
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Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

More cheap stays in Southeast Missouri
More cheap stays in Southeast Missouri

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
The price is SAR 255 per night from Mar 6 to Mar 7
SAR 255
SAR 291 total
includes taxes & fees
6 Mar - 7 Mar
7.2/10 Good! (1,006 reviews)
Stay near popular Southeast Missouri attractions
Stay near popular Southeast Missouri attractions

Elephant Rocks State Park
5/5(13 reviews)
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
Recent reviews of Southeast Missouri hotels
Recent reviews of Southeast Missouri hotels

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
5/5 Excellent
"We enjoyed our stay and would recommend "
A verified traveler stayed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Posted 8 hours ago
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Explore a world of travel with Expedia
Hotels in Southeast Missouri Neighborhoods
Stay near popular Southeast Missouri attractions
- Hotels near Elephant Rocks State Park
- Hotels near Johnson's Shut-ins State Park
- Hotels near Southeast Missouri State University
- Hotels near Lake Wappapello
- Hotels near Ozark National Scenic Riverways
- Hotels near Echo Bluff State Park
- Hotels near Isle Casino Cape Girardeau
- Hotels near Century Casino Caruthersville
- Hotels near Bonne Terre Mine
- Hotels near Big Spring
- Hotels near Alley Spring & Mill
- Hotels near Taum Sauk Mountain State Park
- Hotels near Current River State Park
- Hotels near Riverfront Bridge Park
- Hotels near Crown Valley Winery
- Hotels near Black River Coliseum
- Hotels near Sainte Genevieve Winery
- Hotels near Trail of Tears State Park
- Hotels near K Bridge Recreation Area
- Hotels near Akers Ferry
More Hotel Options in Southeast Missouri
- Adults Only Resorts & Hotels in Southeast Missouri
- Adventure Hotels in Southeast Missouri
- Business Hotels in Southeast Missouri
- Casinos in Southeast Missouri
- Cheap Hotels in Southeast Missouri
- Family Hotels in Southeast Missouri
- Golf Hotels in Southeast Missouri
- Historic Hotels in Southeast Missouri
- Hotel Wedding Venues in Southeast Missouri
- Hotel with a Concierge in Southeast Missouri
- Hotels with Bars in Southeast Missouri
- Hotels with Free Parking in Southeast Missouri
- Hotels with Hot Tubs in Southeast Missouri
- Hotels with Waterslides in Southeast Missouri
- Hotels with WiFi in Southeast Missouri
- Hotels with a Pool in Southeast Missouri
- Hotels with an Indoor Pool in Southeast Missouri
- Hotels with smoking rooms in Southeast Missouri
- Luxury Hotels in Southeast Missouri
- Pet-friendly Hotels in Southeast Missouri
- Resorts & Hotels with Spas in Southeast Missouri
- Romantic Hotels in Southeast Missouri
- Shopping Hotels in Southeast Missouri
- Ski Hotels in Southeast Missouri
- Winery Hotels in Southeast Missouri
More Accommodation Types in Southeast Missouri
- Vacation Homes in Southeast Missouri
- Cabin Rentals in Southeast Missouri
- Cottages in Southeast Missouri
- Apartments in Southeast Missouri
- Motels in Southeast Missouri
- Farmstay in Southeast Missouri
- RV Parks in Southeast Missouri
- Condo Rentals in Southeast Missouri
- Lodges in Southeast Missouri
- Aparthotels in Southeast Missouri
- B&B in Southeast Missouri
- Villas in Southeast Missouri
Hotels near Southeast Missouri Airports
Other Hotels near Southeast Missouri, Missouri
- Cape Girardeau Hotels
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- Ste Genevieve Hotels
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Explore more hotels
- The Farmstead Hotel
- Drury Inn & Suites Cape Girardeau
- Courtyard by Marriott Cape Girardeau Downtown
- Pear Tree Inn Sikeston
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Quality Inn
- Pear Tree Inn Cape Girardeau Near the Medical Center
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