Photo by Ryan Coleman

Find Casinos in Sikeston, MO

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Compare Sikeston Casinos room rates, reviews, and availability. Most hotels are fully refundable.

Town House Inn Cape Giradreau

2.5 star property
6.0 out of 10, (159)
"Nice"
The price is SAR 207
SAR 241 total
includes taxes & fees
5 Jan - 6 January 2025
Town House Inn Cape Giradreau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

2.5 star property
9.4 out of 10, Exceptional, (1001)
"Staff was amazing and the suite was very nice and it felt homey."
The price is SAR 372
SAR 420 total
includes taxes & fees
12 Jan - 13 January 2025
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1002)
"clean room. barking dog"
The price is SAR 244
SAR 275 total
includes taxes & fees
24 Dec - 25 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center

Candlewood Suites Cape Girardeau, an IHG Hotel

2.5 star property
8.2 out of 10, Very Good, (708)
"Very spacious room with very comfortable bed."
The price is SAR 248
SAR 300 total
includes taxes & fees
5 Jan - 6 January 2025
Candlewood Suites Cape Girardeau, an IHG Hotel

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1003)
"Always a great place to stay. "
The price is SAR 240
SAR 271 total
includes taxes & fees
30 Dec - 31 Dec
Pear Tree Inn Cape Girardeau West

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (845)
"The staff was super friendly. Really good!"
The price is SAR 338
SAR 381 total
includes taxes & fees
10 Jan - 11 January 2025
Drury Inn & Suites Cape Girardeau

Quality Inn

2.5 star property
7.0 out of 10, Good, (523)
"It was quite and clean"
The price is SAR 229
SAR 258 total
includes taxes & fees
24 Dec - 25 Dec
Quality Inn

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (671)
"Great customer service"
The price is SAR 304
SAR 329 total
includes taxes & fees
24 Dec - 25 Dec
Comfort Suites Jackson-Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Searching for casino hotels in Sikeston?
Tourists speak highly of the family-friendly activities, shopping, and local cuisine.
How many hotels that are good for gaming can I expect to find in Sikeston?
You won’t need a stroke of luck to find something that suits with one of Expedia’s 15 casino hotels in Sikeston.
When should I take my casino trip to Sikeston?
You might spend a lot of your vacation inside, but if you want to see more of the area, looking at local weather trends is a good idea. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What is there to do in Sikeston?
If you’re interested in local cultural spots, you can check out Sikeston Depot Museum and Front Street Studio & Art Gallery. Nature enthusiasts will appreciate the riverfront, and places to get outdoors include Central Park, Shawnee National Forest, and Mississippi River. If you’re looking for more to see and do, you can add The Book Bug and Boot Heel Golf Club to your list.
What are my transportation options for my casino getaway to Sikeston?
Here are some transportation options in Sikeston: You can arrange a flight to the nearest airport, which is Cairo, IL (CIR-Cairo Regional), 23.8 mi (38.3 km) from the city center. If you’d like to explore around the area, you may want a rental car for your journey.