Photo by Ryan Coleman

Find Casinos in Sikeston, MO

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Pick from 9 Sikeston Casinos and compare room rates, reviews, and availability. Most hotels are fully refundable.

Town House Inn Cape Giradreau
Exterior
Town House Inn Cape Giradreau
2.5 star property
6.0 out of 10, (155)
"It was a room to lay my head at night. Shower didn't work, ceiling paint was peeling and heavy smell of marijuana even though it was a no smoking room!"
The price is SAR 207
SAR 241 total
includes taxes & fees
20 Nov - 21 Nov
Town House Inn Cape Giradreau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 star property
9.4 out of 10, Exceptional, (1000)
"Our only complaint was the kids channels weren’t working on the TV. Other than that clean, quiet, polite, good eating area"
The price is SAR 357
SAR 396 total
includes taxes & fees
1 Dec - 2 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Pear Tree Inn Cape Girardeau Near the Medical Center
Exterior
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, (1003)
"Breakfast was not what we expected…. It was no better than some cheaper hotels I have stayed at!!!! Waffles and cereal was basically the choices you had!"
The price is SAR 223
SAR 252 total
includes taxes & fees
27 Nov - 28 Nov
Pear Tree Inn Cape Girardeau Near the Medical Center
Candlewood Suites Cape Girardeau, an IHG Hotel
Exterior
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 star property
8.2 out of 10, Very Good, (695)
"This was my first time at candlewood suites, we went for a fun weekend at Cape Con and we were so impressed with our room! It was an amazing value and the rooms were extremely clean and well stocked. The pool was also a plus!! We will absolutely be returning, Candlewood made us want to make this a location for a yearly trip! Thank you for the service! "
The price is SAR 323
SAR 385 total
includes taxes & fees
15 Dec - 16 Dec
Candlewood Suites Cape Girardeau, an IHG Hotel
Auburn Place Hotel And Suites
Indoor pool
Auburn Place Hotel And Suites
2.5 star property
8.8 out of 10, Excellent, (1005)
"Sorry that they tearing down this wonderful place"
Auburn Place Hotel And Suites
Pear Tree Inn Cape Girardeau West
Exterior
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1001)
"Stayed here with my wife and daughter while in town to attend a concert happening after the rodeo. Everything with this property was great. The room was clean, the beds & bedding were clean and comfortable, the highway is easy to access, and the staff was great. No complaints and would stay here again. "
The price is SAR 270
SAR 305 total
includes taxes & fees
4 Dec - 5 Dec
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Cape Girardeau
Exterior
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (813)
"Great"
The price is SAR 321
SAR 362 total
includes taxes & fees
22 Nov - 23 Nov
Drury Inn & Suites Cape Girardeau
Quality Inn
Exterior
Quality Inn
2.5 star property
7.0 out of 10, Good, (516)
"We really enjoyed our 2 day stay there. Staff nice, rooms clean, parking was easy. My only complaint was breakfast. There could/should have had a better selection. Overall....a great stay. "
The price is SAR 229
SAR 258 total
includes taxes & fees
17 Nov - 18 Nov
Quality Inn
Comfort Suites Jackson-Cape Girardeau
Exterior
Comfort Suites Jackson-Cape Girardeau
2.5 star property
8.2 out of 10, Very Good, (668)
"Quiet and comfortable. Room had a few minor problems - brown stains on tub, torn upholstery - but these were minor. Breakfast was okay. Hard to find any staff but they were friendly when found. "
The price is SAR 273
SAR 292 total
includes taxes & fees
1 Dec - 2 Dec
Comfort Suites Jackson-Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Searching for casino hotels in Sikeston?
Tourists speak highly of the family-friendly activities, shopping, and local cuisine.
How many hotels that are good for gaming can I expect to find in Sikeston?
You won’t need a stroke of luck to find something that suits with one of Expedia’s 13 casino hotels in Sikeston.
When should I take my casino trip to Sikeston?
You might spend a lot of your vacation inside, but if you want to see more of the area, looking at local weather trends is a good idea. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What is there to do in Sikeston?
If you’re interested in local cultural spots, you can check out Sikeston Depot Museum and Front Street Studio & Art Gallery. Nature enthusiasts will appreciate the riverfront, and places to get outdoors include Central Park and Mississippi River. If you’re looking for more to see and do, you can add The Book Bug and Boot Heel Golf Club to your list.
What are my transportation options for my casino getaway to Sikeston?
Here are some transportation options in Sikeston: You can arrange a flight to the nearest airport, which is Cairo, IL (CIR-Cairo Regional), 23.8 mi (38.3 km) from the city center. If you’d like to explore around the area, you may want a rental car for your journey.