Find hotels in Cairo, IL from SAR 239

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Tonight
14 Rab. II - 15 Rab. II
Tomorrow
15 Rab. II - 16 Rab. II
This weekend
18 Rab. II - 20 Rab. II
Next weekend
25 Rab. II - 27 Rab. II

Filter by

Guest rating
Guest rating
Star rating

Compare 25 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Quality Inn Cairo I-57
Lobby

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (250)
"We had a quiet and convenient one night stay. "
The price is SAR 284
SAR 315 total
includes taxes & fees
14 May - 15 May
Quality Inn Cairo I-57
La Center Motel
Basic Double Room | Free WiFi

La Center Motel

2.0 star property
7.6 out of 10, Good, (13)
"Clean, friendly, easy parking, good price, remodel restroom, good refrigerator and microwave "
The price is SAR 244
SAR 281 total
includes taxes & fees
15 Apr - 16 Apr
La Center Motel
Regency Inn
Reception

Regency Inn

2.0 star property
The price is SAR 358
SAR 398 total
includes taxes & fees
15 Apr - 16 Apr
Regency Inn
Eagle Inn Charleston
Desk, iron/ironing board, free WiFi, alarm clocks

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (96)
"Comfortable bed, easy access to room"
The price is SAR 239
SAR 266 total
includes taxes & fees
15 Apr - 16 Apr
Eagle Inn Charleston
Super 8 by Wyndham Charleston/Sikeston East MO
Front of property - evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (548)
"The carpet in the room needs to be vacuumed."
The price is SAR 247
SAR 274 total
includes taxes & fees
20 Apr - 21 Apr
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (375)
"Staff were very friendly. Room was spacious and well designed."
The price is SAR 269
SAR 298 total
includes taxes & fees
4 May - 5 May
Quality Inn Charleston - Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Cairo
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Cairo

Escape to quaint Cairo! Enjoy its ruins, history, and library.

See all hotels in Cairo

Frequently asked questions

Where is the best place for a stay in Cairo?

Based on our traveler data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your trip to the area are Super 8 by Wyndham Charleston/Sikeston East MO and Quality Inn Charleston - Sikeston. See all available top hotels, or vacation rentals in Cairo.

What are some of the best vacation rentals in Cairo?

Welcome campers, hikers, fishermen, girls' weekend wine getaways!!: This vacation home rental near Cairo is located in a rural location and has a fireplace, a selection of games, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities like a stovetop and a microwave can make your vacation run smoothly. See all vacation rentals in Cairo.

If I need to cancel my hotel reservation in Cairo, will I receive a refund?

Yes! Most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.

Where can I learn more about changing or cancelling my trip to Cairo?

For more information about updating your trip to Cairo or cancelling it, head over to our customer service page.

Where is the best hotel to stay close to Fort Defiance?

Quality Inn Cairo I-57 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 4.9 mi (7.8 km) from Fort Defiance. Other good options around the area include Victorian Splendor in So. Illinois: wallmanor.com and Eagle Inn Charleston.

What's the best hotel for staying near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Cairo like?

Visitors can enjoy all that Cairo has to offer including the restaurants, entertainment choices, and riverfront. This city also attracts tourists with its small-town vibe. There are 25 hotels and other accommodations in the surrounding area. Find out more about Cairo.

What should I see while I'm in Cairo?

A couple of favorite places to visit are Mississippi River and Fort Defiance State Park. You'll also find Mound City National Cemetery and Columbus-Belmont State Park in the area. Check out what more to see and do in Expedia's Cairo guide.

What's the seasonal weather like in Cairo?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.