Find hotels in Cairo, IL from SAR 216

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Compare 24 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Super 8 by Wyndham Charleston/Sikeston East MO
Front of property - evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (533)
"I just want to tell you I stay here a lot. I had never read the reviews before and it didn’t sound like a place I wanted to stay. But the rooms are big. On one side, you can come in from the outside or inside. It is close to halfway for me. Easy to get to. "
The price is SAR 216
SAR 240 total
includes taxes & fees
1 Dec - 2 Dec
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Cairo I-57
Exterior

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (237)
"The room was very clean and the breakfast was pretty good. No complaints"
The price is SAR 225
SAR 248 total
includes taxes & fees
13 Dec - 14 Dec
Quality Inn Cairo I-57
Quality Inn Charleston - Sikeston
Exterior

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (359)
"Great bed. "
The price is SAR 216
SAR 233 total
includes taxes & fees
21 Dec - 22 Dec
Quality Inn Charleston - Sikeston
Eagle Inn Charleston
Exterior

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (95)
"Comfortable bed, easy access to room"
The price is SAR 260
SAR 289 total
includes taxes & fees
26 Nov - 27 Nov
Eagle Inn Charleston
Charming 3-bedroom house near ball park in quiet neighborhood
Exterior detail

Charming 3-bedroom house near ball park in quiet neighborhood

10.0 out of 10, Exceptional, (3)
"The house is perfect, great location, very clean and well organized. The host has everything in order from Check-in to Check-out and everything in between. Great Place"
The price is SAR 338
SAR 603 total
includes taxes & fees
29 Nov - 30 Nov
Charming 3-bedroom house near ball park in quiet neighborhood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place for a stay in Cairo?

Based on our traveler data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your trip to the area are Super 8 by Wyndham Charleston/Sikeston East MO and Quality Inn Charleston - Sikeston. See all available top hotels, or vacation rentals in Cairo.

What are some of the best vacation rentals in Cairo?

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286: This vacation home rental near Cairo is located in a rural location and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in Cairo.

If I need to cancel my hotel reservation in Cairo, will I receive a refund?

Yes! Most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.

Where can I learn more about changing or cancelling my trip to Cairo?

For more information about updating your trip to Cairo or cancelling it, head over to our customer service page.

Where is the best hotel to stay close to Fort Defiance?

Quality Inn Cairo I-57 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 4.9 mi (7.8 km) from Fort Defiance. Other good options around the area include Victorian Splendor in So. Illinois: wallmanor.com and Eagle Inn Charleston.

What's the best hotel for staying near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Cairo like?

Visitors can enjoy all that Cairo has to offer including the restaurants, entertainment choices, and riverfront. This city also attracts tourists with its small-town vibe. There are 26 hotels and other accommodations in the surrounding area. Find out more about Cairo.

What should I see while I'm in Cairo?

The picturesque setting of Mississippi River and Fort Defiance State Park exemplify the area's natural beauty. You'll also find Ballard Wildlife Management Area and Columbus-Belmont State Park in the area. Check out what more to see and do in Expedia's Cairo guide.

What's the seasonal weather like in Cairo?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.