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Discover 4,547 Otay Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.
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Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
7.6 out of 10, Good, (1397)
The price is SAR 477
SAR 537 total
includes taxes & fees
23 Mar - 24 Mar
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Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay Mesa
7.2 out of 10, Good, (1001)
The price is SAR 393
SAR 442 total
includes taxes & fees
23 Mar - 24 Mar
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Sycuan Casino Resort
Sycuan Casino Resort
9.2 out of 10, Wonderful, (1101)
The price is SAR 323
SAR 400 total
includes taxes & fees
3 Mar - 4 Mar
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Days Inn by Wyndham San Diego-East/El Cajon
Days Inn by Wyndham San Diego-East/El Cajon
7.8 out of 10, Good, (1006)
The price is SAR 335
SAR 369 total
includes taxes & fees
10 Mar - 11 Mar
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Best Western Santee Lodge
Best Western Santee Lodge
8.0 out of 10, Very Good, (483)
The price is SAR 435
SAR 480 total
includes taxes & fees
2 Mar - 3 Mar
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Super 8 by Wyndham El Cajon/San Diego
Super 8 by Wyndham El Cajon/San Diego
7.4 out of 10, Good, (1004)
The price is SAR 334
SAR 368 total
includes taxes & fees
3 Mar - 4 Mar
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Where to stay in Otay Mesa
Where to stay in Otay Mesa
Hotels in top San Diego neighborhoods Learn more about Otay Mesa
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Downtown San Diego
2 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Recent reviews of Otay Mesa hotels
Recent reviews of Otay Mesa hotels
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The Dana on Mission Bay
5/5 Excellent
"Great place and location "
A verified traveler stayed at The Dana on Mission Bay
Posted 12 hours ago
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Otay Mesa Hotels by Star Rating
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