Find all hotels by Best Western in Otay Mesa, CA from SAR104
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Compare rooms and suites by Best Western in Otay Mesa with rates, reviews, and availability. Most hotels are fully refundable.
Recent reviews of Otay Mesa hotels
Recent reviews of Otay Mesa hotels
5/5 Excellent
"We loved it"
A verified traveler stayed at Marriott Marquis San Diego Marina
Posted 20 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels near popular San Diego Attractions
More Hotel Options in Otay Mesa
- Beach Hotels (2)
- Business Hotels (2)
- Casinos (2)
- Cheap Hotels (2)
- Family Hotels (2)
- Golf Hotels (2)
- Historic Hotels (2)
- Hotels with Free Parking (2)
- Hotels with Hot Tubs (2)
- Hotels with WiFi (2)
- Hotels with a Pool (2)
- Hotels with smoking rooms (1)
- Luxury Hotels (1)
- Resorts & Hotels with Spas (1)
- Shopping Hotels (2)
- Winery Hotels (2)
Explore more hotels
- Legacy Resort Hotel & Spa
- San Diego Mission Bay Resort
- Sheraton San Diego Hotel and Marina
- Manchester Grand Hyatt San Diego
- Hyatt Regency Mission Bay Spa and Marina
- Loews Coronado Bay Resort
- Marriott Marquis San Diego Marina
- Hilton San Diego Bayfront
- Comfort Inn Sea World Area
- DoubleTree by Hilton Hotel San Diego - Mission Valley
- Embassy Suites by Hilton San Diego Bay Downtown
- Palihotel San Diego
- Humphreys Half Moon Inn
- Kings Inn San Diego
- Best Western Plus Island Palms Hotel & Marina
- The Atwood Hotel San Diego - SeaWorld/Zoo
- Lafayette Hotel & Club
- AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
- The Horton Grand, Downtown/Gaslamp Quarter
- San Diego Marriott Gaslamp Quarter