Find all hotels by Motel 6 in Otay Mesa, CA from SAR 248
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Tonight
Tomorrow
This weekend
Next weekend
Compare rooms and suites by Motel 6 in Otay Mesa with rates, reviews, and availability. Most hotels are fully refundable.

Motel 6 El Cajon, CA - San Diego
Motel 6 El Cajon, CA - San Diego
7.2 out of 10, Good, (1148)
The price is SAR 248
SAR 274 total
includes taxes & fees
12 May - 13 May

Motel 6 San Diego, CA - Downtown
Motel 6 San Diego, CA - Downtown
6.4 out of 10, (1163)
The price is SAR 334
SAR 384 total
includes taxes & fees
13 Apr - 14 Apr

Motel 6 San Diego, CA - Hotel Circle - Mission Valley
Motel 6 San Diego, CA - Hotel Circle - Mission Valley
6.8 out of 10, (1368)
The price is SAR 307
SAR 347 total
includes taxes & fees
14 Apr - 15 Apr

Motel 6 Chula Vista, CA - San Diego
Motel 6 Chula Vista, CA - San Diego
6.0 out of 10, (1868)
The price is SAR 258
SAR 296 total
includes taxes & fees
20 Apr - 21 Apr

Motel 6 San Diego Airport - Harbor
Motel 6 San Diego Airport - Harbor
6.8 out of 10, (941)
The price is SAR 332
SAR 373 total
includes taxes & fees
15 Apr - 16 Apr

Motel 6 San Ysidro, CA - San Diego - Border
Motel 6 San Ysidro, CA - San Diego - Border
7.0 out of 10, Good, (1353)
The price is SAR 285
SAR 322 total
includes taxes & fees
21 Apr - 22 Apr

Motel 6 La Mesa, CA
Motel 6 La Mesa, CA
7.2 out of 10, Good, (1002)
The price is SAR 394
SAR 434 total
includes taxes & fees
13 Apr - 14 Apr

Motel 6 La Mesa, CA - San Diego
Motel 6 La Mesa, CA - San Diego
7.4 out of 10, Good, (879)
The price is SAR 334
SAR 368 total
includes taxes & fees
17 Apr - 18 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Recent reviews of Otay Mesa hotels
Recent reviews of Otay Mesa hotels

Legacy Resort Hotel & Spa
5/5 Excellent
Highly Recommend
"Room is clean , bed comfortable , fluffy towels. Nice lobby. Friendly service.
Pool area clean. Easy parking. "
A verified traveler stayed at Legacy Resort Hotel & Spa
Posted 14 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Otay Mesa Hotels by Brand
Hotels near popular San Diego Attractions
- Hotels near Cross Border Xpress
- Hotels near San Diego Zoo
- Hotels near San Diego Convention Center
- Hotels near Mission Bay
- Hotels near Mission Beach
- Hotels near San Ysidro Border Crossing
- Hotels near Petco Park
- Hotels near San Diego State University
- Hotels near Balboa Park
- Hotels near Port of San Diego
More Hotel Options in Otay Mesa
- Beach Hotels in Otay Mesa
- Business Hotels in Otay Mesa
- Casinos in Otay Mesa
- Cheap Hotels in Otay Mesa
- Family Hotels in Otay Mesa
- Golf Hotels in Otay Mesa
- Historic Hotels in Otay Mesa
- Hotels with Free Parking in Otay Mesa
- Hotels with Hot Tubs in Otay Mesa
- Hotels with WiFi in Otay Mesa
- Hotels with a Pool in Otay Mesa
- Hotels with smoking rooms in Otay Mesa
- Luxury Hotels in Otay Mesa
- Resorts & Hotels with Spas in Otay Mesa
- Shopping Hotels in Otay Mesa
- Winery Hotels in Otay Mesa
More Accommodation Types in Otay Mesa
Explore more hotels
- Best Western Seven Seas
- Legacy Resort Hotel & Spa
- DoubleTree by Hilton Hotel San Diego - Mission Valley
- Kings Inn San Diego
- Hyatt Regency Mission Bay Spa and Marina
- Comfort Inn Sea World Area
- Palihotel San Diego Gaslamp Quarter
- Sheraton San Diego Resort
- The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
- Loews Coronado Bay Resort
- Handlery Hotel
- Embassy Suites by Hilton San Diego Bay Downtown
- Hard Rock Hotel San Diego
- Manchester Grand Hyatt San Diego
- Days Inn by Wyndham San Diego Hotel Circle
- Marriott Marquis San Diego Marina
- Alma San Diego Downtown, a Tribute Portfolio Hotel
- Pendry San Diego
- The Sofia Hotel
- La Pensione Hotel