Find 5 Star Hotels in Otay Mesa, CA from SAR 525

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Check availability on Otay Mesa 5 Star Hotels

Compare Otay Mesa 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Pendry San Diego
Front of property - evening/night

Pendry San Diego

5.0 star property
9.2 out of 10, Wonderful, (1003)
"Nice lounge and amenity , pool is great!"
The price is SAR 1,182
SAR 1,523 total
includes taxes & fees
20 Feb - 21 Feb
Pendry San Diego
THE US GRANT, a Luxury Collection Hotel, San Diego
Lobby lounge

THE US GRANT, a Luxury Collection Hotel, San Diego

5.0 star property
9.0 out of 10, Wonderful, (1003)
"An unbelievable hotel in a declining area of downtown. San Diego like most California ities is on the decline. I grew up here and remember the days of Horton Plaza and the Gaslamp Quarter and its really declined unfortunately. The hotel is fabulous though. "
The price is SAR 1,172
SAR 1,321 total
includes taxes & fees
20 Feb - 21 Feb
THE US GRANT, a Luxury Collection Hotel, San Diego
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Otay Mesa.
San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter

660 K St, San Diego, CA
The price is SAR 603 per night from Feb 7 to Feb 8
SAR 603
SAR 679 total
includes taxes & fees
7 Feb - 8 Feb
8.4/10 Very Good! (1,302 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Otay Mesa?
The amount you pay for a 5-star hotel in Otay Mesa can vary depending on when you decide to travel and how long you plan to be away, among a number of factors. Take advantage of our price per night filter and other search tools to score the best deal on a luxurious getaway.

  • Search for the lowest price per night from SAR 525

What makes a hotel 5 stars in Otay Mesa?
From high-end dining venues and 24-hour fitness centers to pools and superior bedding, the 5-star experience in Otay Mesa is all about relaxation and luxury. But it requires more than just top-notch amenities to earn a 5-star rating. Hotels must also deliver superb guest-focused services like in-room massage treatments, on-site dry cleaning and laundry and 24-hour room service.
Are there any 5-star all-inclusive resorts in Otay Mesa?
Find a luxury retreat that includes your room, meals, activities and entertainment in Otay Mesa with Expedia’s filter tool. Search for resorts with a 5-star rating and select the “All inclusive” filter. Double-check what’s included in the upfront price. That way, you’re ready to take advantage of the many perks on offer from the moment you arrive.
Are there any 5-star vacation rentals in Otay Mesa?
Although there aren’t any 5-star vacation rentals in Otay Mesa on our site, we have a range of escapes that promise a fantastic getaway. Find one that suits your style by checking out our vacation rentals in Otay Mesa.