Find Resorts & Hotels with Spas in San Luis Obispo, CA

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Check availability on San Luis Obispo Resorts & Hotels with Spas

Compare San Luis Obispo Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Quality Suites Downtown San Luis Obispo

3.0 star property
9.4 out of 10, Exceptional, (1006)
"It was an amazing hotel!!! Very friendly helpful staff, convenient location, and wonderful amenities! "
The price is SAR 521
SAR 668 total
includes taxes & fees
23 Feb - 24 Feb
Quality Suites Downtown San Luis Obispo

Hotel San Luis Obispo

4.5 star property
9.4 out of 10, Exceptional, (468)
"Very nice property. Bigger than it looked from the outside. The entire property felt very open and bright - even the hallways! The room was comfortable. Location was convenient. Just across the street ftom the Mission. We parked across the street in the public lot. We are too impatient to wait for the valet! Appreciated the glass bottles of water in the room along with the fridge. Had dinner at the steakhouse which was good. Did not eat breakfast at the hotel so cant comment."
The price is SAR 1,279
SAR 1,452 total
includes taxes & fees
2 Mar - 3 Mar
Hotel San Luis Obispo

University Inn

2.0 star property
8.2 out of 10, Very Good, (1001)
"Room was updated, clean and comfortable. Breakfast was simple and not many choices. Overall, quiet and clean motel."
The price is SAR 278
SAR 421 total
includes taxes & fees
25 Feb - 26 Feb
University Inn

Madonna Inn

3.5 star property
9.2 out of 10, Wonderful, (1128)
"We really enjoyed our stay at the Madonna Inn. It rained nearly the entire stay but still managed to get some time in at the Jaquizzi! The fireplace in our room made our stay extra cozy. Looking forward to going back again!"
The price is SAR 548
SAR 749 total
includes taxes & fees
27 Feb - 28 Feb
Madonna Inn

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

3.0 star property
9.0 out of 10, Wonderful, (1403)
"Feels like brand new property. Everything is in great condition, plenty of parking (not free). Close by to downtown and exit to highway. A nice restaurant near by."
The price is SAR 453
SAR 515 total
includes taxes & fees
3 Mar - 4 Mar
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

Vagabond Inn San Luis Obispo

2.0 star property
8.4 out of 10, Very Good, (1056)
"did it’s job perfectly! will stay again when going to slo"
The price is SAR 192
SAR 263 total
includes taxes & fees
24 Feb - 25 Feb
Vagabond Inn San Luis Obispo

Mission Inn San Luis Obispo

2.0 star property
7.8 out of 10, Good, (784)
"Comfy "
The price is SAR 214
SAR 285 total
includes taxes & fees
24 Feb - 25 Feb
Mission Inn San Luis Obispo

HOTEL CERRO, Autograph Collection

4.0 star property
9.2 out of 10, Wonderful, (435)
"Beautiful hotel in a great location for walking downtown San Luis! The restaurant has great breakfasts and in the evening a very nice bar! "
The price is SAR 1,009
SAR 1,259 total
includes taxes & fees
2 Mar - 3 Mar
HOTEL CERRO, Autograph Collection

Motel 6 San Luis Obispo, CA - South

2.0 star property
8.2 out of 10, Very Good, (1005)
"Great as always!!!"
The price is SAR 281
SAR 320 total
includes taxes & fees
25 Feb - 26 Feb
Motel 6 San Luis Obispo, CA - South

Best Western Plus Royal Oak Hotel

2.5 star property
8.6 out of 10, Excellent, (1001)
"The location in San Luis Obispo, just a few exits from Cal Poly, was lovely. The property was pet-friendly and included a fenced-off area for pets. The rooms were clean and decent, and the air conditioner worked well. The hotel staff were warm and courteous, while the breakfast staff were exceptional, although the breakfast selection was average. "
The price is SAR 481
SAR 546 total
includes taxes & fees
9 Mar - 10 Mar
Best Western Plus Royal Oak Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in San Luis Obispo?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers love the wineries and restaurants in San Luis Obispo. Enjoy the art galleries and beaches during your vacation. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in San Luis Obispo?
Madonna Inn is a top spa hotel featuring a fitness center, tennis courts, a bar, and an outdoor pool. Spend an afternoon at The Spa at Madonna Inn. where you’ll find facials, body scrubs, and Swedish massages and more. Other popular spa hotels in San Luis Obispo include Hotel San Luis Obispo and HOTEL CERRO, Autograph Collection.
How many spa hotels will I find in San Luis Obispo?
Among Expedia’s 216 accommodation options in San Luis Obispo, there are 3 spa hotels.
What's there to see and do in San Luis Obispo?
Enjoy all that San Luis Obispo has to offer and visit Fremont Theater, Downtown SLO Farmers’ Market, and San Luis Obispo Superior Court. If you have extra time while you’re in the area, you might want to see Mission San Luis Obispo de Tolosa and Ah Louis Store.
What is a San Luis Obispo spa hotel?
Spa hotels in San Luis Obispo provide lodging and have a full on-site spa which offers services like therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.