Find Resorts & Hotels with Spas in San Luis Obispo, CA

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Compare San Luis Obispo Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Quality Suites Downtown San Luis Obispo
Exterior

Quality Suites Downtown San Luis Obispo

3.0 star property
9.4 out of 10, Exceptional, (1003)
"The hotel was old,but newly renovated. The bed and pillows were very good. The room was large and comfortable. "
The price is SAR 402
SAR 533 total
includes taxes & fees
2 Jan - 3 January 2025
Quality Suites Downtown San Luis Obispo
Hotel San Luis Obispo
Exterior

Hotel San Luis Obispo

4.5 star property
9.4 out of 10, Exceptional, (450)
"Incredible location. The staff is amazing! "
The price is SAR 1,349
SAR 1,531 total
includes taxes & fees
23 Dec - 24 Dec
Hotel San Luis Obispo
University Inn
Exterior detail

University Inn

2.0 star property
8.2 out of 10, Very Good, (984)
"Really nice place:)"
The price is SAR 275
SAR 419 total
includes taxes & fees
28 Dec - 29 Dec
University Inn
Madonna Inn
Interior entrance

Madonna Inn

3.5 star property
9.2 out of 10, Wonderful, (1100)
"It was fun with the theme room, love it "
The price is SAR 606
SAR 815 total
includes taxes & fees
5 Jan - 6 January 2025
Madonna Inn
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
Room

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

3.0 star property
9.0 out of 10, Wonderful, (1342)
"Wonderful hotel. Great bed, great breakfast. Friendly staff"
The price is SAR 393
SAR 446 total
includes taxes & fees
5 Jan - 6 January 2025
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
Vagabond Inn San Luis Obispo
Reception

Vagabond Inn San Luis Obispo

2.0 star property
8.4 out of 10, Very Good, (1034)
"It was just a fanily stay"
The price is SAR 251
SAR 330 total
includes taxes & fees
1 Jan - 2 January 2025
Vagabond Inn San Luis Obispo
Mission Inn San Luis Obispo
Property entrance

Mission Inn San Luis Obispo

2.0 star property
7.8 out of 10, Good, (778)
"Great stay, perfect for what we needed."
The price is SAR 259
SAR 337 total
includes taxes & fees
24 Dec - 25 Dec
Mission Inn San Luis Obispo
HOTEL CERRO, Autograph Collection
Reception

HOTEL CERRO, Autograph Collection

4.0 star property
9.2 out of 10, Wonderful, (428)
"Pleasantly surprised the Beauty of the room and amenities. "
The price is SAR 1,011
SAR 1,262 total
includes taxes & fees
29 Dec - 30 Dec
HOTEL CERRO, Autograph Collection
Motel 6 San Luis Obispo, CA - South
Lobby

Motel 6 San Luis Obispo, CA - South

2.0 star property
8.2 out of 10, Very Good, (1000)
"Great customer service "
The price is SAR 282
SAR 320 total
includes taxes & fees
20 Jan - 21 January 2025
Motel 6 San Luis Obispo, CA - South
Best Western Plus Royal Oak Hotel
Pool

Best Western Plus Royal Oak Hotel

2.5 star property
8.6 out of 10, Excellent, (1003)
"Super easy and convenient. "
The price is SAR 398
SAR 452 total
includes taxes & fees
30 Dec - 31 Dec
Best Western Plus Royal Oak Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in San Luis Obispo

Frequently asked questions

Looking for a spa hotel in San Luis Obispo?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers love the wineries and restaurants in San Luis Obispo. Enjoy the art galleries and beaches during your vacation. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in San Luis Obispo?
Madonna Inn is a top spa hotel featuring a fitness center, tennis courts, a bar, and an outdoor pool. Spend an afternoon at The Spa at Madonna Inn. where you’ll find facials, body scrubs, and Swedish massages and more. Other popular spa hotels in San Luis Obispo include HOTEL CERRO, Autograph Collection and Hotel San Luis Obispo.
How many spa hotels will I find in San Luis Obispo?
Among Expedia’s 215 accommodation options in San Luis Obispo, there are 3 spa hotels.
What's there to see and do in San Luis Obispo?
Enjoy all that San Luis Obispo has to offer and visit Fremont Theater, Downtown SLO Farmers’ Market, and San Luis Obispo Superior Court. If you have extra time while you’re in the area, you might want to see Bubblegum Alley and Mission San Luis Obispo de Tolosa.
What is a San Luis Obispo spa hotel?
Spa hotels in San Luis Obispo provide lodging and have a full on-site spa which offers services like therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.