Photo by Linda Cronan

Find hotels in Medical Center District, San Antonio from SAR 152

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Discover 4,252 Medical Center District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Drury Inn & Suites San Antonio Northwest Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1223)
"Amazing staff, very clean and great location."
The price is SAR 375
SAR 443 total
includes taxes & fees
8 May - 9 May
Drury Inn & Suites San Antonio Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 star property
8.4 out of 10, Very Good, (1005)
"Great location, clean hotel, good bar and restaurant "
The price is SAR 357
SAR 424 total
includes taxes & fees
2 Jun - 3 Jun
San Antonio Marriott Northwest Medical Center

Courtyard by Marriott Medical Center San Antonio

3.0 star property
8.6 out of 10, Excellent, (1004)
"Great stay"
The price is SAR 368
SAR 434 total
includes taxes & fees
11 May - 12 May
Courtyard by Marriott Medical Center San Antonio

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3.0 star property
8.6 out of 10, Excellent, (2476)
"Loved the friendliness of staff and everything we had planned in town was conveniently close"
The price is SAR 372
SAR 440 total
includes taxes & fees
6 May - 7 May
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 star property
9.0 out of 10, Wonderful, (838)
"Great place to stay. "
The price is SAR 345
SAR 403 total
includes taxes & fees
18 May - 19 May
Fairfield Inn & Suites by Marriott San Antonio Medical Center

SpringHill Suites by Marriott San Antonio Medical Center/NW

3.0 star property
8.8 out of 10, Excellent, (1002)
"Perfect to family with little children. "
The price is SAR 409
SAR 483 total
includes taxes & fees
11 May - 12 May
SpringHill Suites by Marriott San Antonio Medical Center/NW

Atria Inn & Suites

2.0 star property
7.8 out of 10, Good, (213)
"Nice place"
The price is SAR 225
SAR 263 total
includes taxes & fees
8 May - 9 May
Atria Inn & Suites

OYO Inn & Suites Medical Center San Antonio

2.0 star property
7.2 out of 10, Good, (207)
"This is a beautiful place to stay ❤️ 💖 "
The price is SAR 240
SAR 280 total
includes taxes & fees
14 May - 15 May
OYO Inn & Suites Medical Center San Antonio

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

3.0 star property
6.6 out of 10, (1004)
"The breakfast was really good and all the staff were so nice!!"
The price is SAR 227
SAR 265 total
includes taxes & fees
18 May - 19 May
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Flex Studios

2.5 star property
6.0 out of 10, (463)
"The staff was very helpful and accommodating. And they were super friendly!"
The price is SAR 194
SAR 229 total
includes taxes & fees
8 May - 9 May
Flex Studios

Studio 6 San Antonio, Tx - Northwest Medical Center

2.0 star property
7.0 out of 10, Good, (137)
"Very peaceful and quiet "
The price is SAR 165
SAR 193 total
includes taxes & fees
11 May - 12 May
Studio 6 San Antonio, Tx - Northwest Medical Center

Park Inn by Radisson

2.0 star property
7.0 out of 10, Good, (1001)
"Very nice and quiet place to stay in the medical center. "
The price is SAR 252
SAR 294 total
includes taxes & fees
18 May - 19 May
Park Inn by Radisson

Studio 6 San Antonio, TX - Medical Center

2.0 star property
6.6 out of 10, (700)
"Hotel in convenient location, for a budget hotel it was fine. Clean and comfy bed and towels. Cant complain for the price! "
The price is SAR 185
SAR 226 total
includes taxes & fees
18 May - 19 May
Studio 6 San Antonio, TX - Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

2.0 star property
6.0 out of 10, (1003)
"Close to restraunts"
The price is SAR 152
SAR 179 total
includes taxes & fees
12 May - 13 May
Motel 6 San Antonio, TX - Northwest Medical Center

Hotel Valencia Riverwalk

4.5 star property
9.4 out of 10, Exceptional, (1896)
"Beautiful hotel and excellent location! "
The price is SAR 618
SAR 810 total
includes taxes & fees
27 May - 28 May
Hotel Valencia Riverwalk

The Westin San Antonio North

4.0 star property
8.6 out of 10, Excellent, (1008)
"Great property. "
The price is SAR 328
SAR 394 total
includes taxes & fees
18 May - 19 May
The Westin San Antonio North

Best Western Plus Lackland Hotel & Suites

2.5 star property
8.8 out of 10, Excellent, (1005)
"Everything about the property was great and close to the base as well. "
The price is SAR 412
SAR 482 total
includes taxes & fees
9 May - 10 May
Best Western Plus Lackland Hotel & Suites

Marriott San Antonio Airport

4.0 star property
8.4 out of 10, Very Good, (1003)
"Overall really good experience nice hotel and food was good"
The price is SAR 446
SAR 528 total
includes taxes & fees
10 May - 11 May
Marriott San Antonio Airport

Menger Hotel

3.5 star property
9.0 out of 10, Wonderful, (3267)
"Great stay beautiful historic hotel"
The price is SAR 459
SAR 542 total
includes taxes & fees
26 May - 27 May
Menger Hotel

Best Western Medical Center North Inn & Suites Near Six Flags

2.5 star property
8.2 out of 10, Very Good, (1416)
"Great stay"
The price is SAR 270
SAR 315 total
includes taxes & fees
8 May - 9 May
Best Western Medical Center North Inn & Suites Near Six Flags
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Medical Center District
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What is Medical Center District like?

Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Are you looking for Medical Center District travel tips? Be sure to check out USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighborhood.

What's a favorite place to stay in Medical Center District?

Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favorite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.

How many hotels will I be able to find in Medical Center District?

Expedia has 124 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.

Where can I learn more about changing or cancelling my trip to Medical Center District?

For more information about changing or cancelling your trip to Medical Center District, go to https://www.expedia.com/service/.

What can I see and do in this San Antonio neighborhood?

USAA Corporate Office Headquarters, Cinemark San Antonio 16, and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and First Unitarian Universalist Church are also worth a visit when you're out sightseeing in San Antonio.