Photo by Linda Cronan

Find 4 Star Hotels in Medical Center District, TX from SAR 312

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Compare Medical Center District 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Riverwalk Plaza
Lobby

Riverwalk Plaza

4.0 star property
8.2 out of 10, Very Good, (4403)
"No parking lot"
The price is SAR 380
SAR 449 total
includes taxes & fees
3 Jan - 4 January 2025
Riverwalk Plaza
Hotel Contessa
Living area

Hotel Contessa

4.0 star property
9.0 out of 10, Wonderful, (2964)
"have stayed here several times and haven’t been ever disappointed "
The price is SAR 635
SAR 811 total
includes taxes & fees
2 Jan - 3 January 2025
Hotel Contessa
Omni La Mansion del Rio
Terrace/patio

Omni La Mansion del Rio

4.0 star property
9.4 out of 10, Exceptional, (2393)
"It was a wonderful experience. The checking in staff to maid service. Everyone was very friendly and helpful. "
The price is SAR 644
SAR 772 total
includes taxes & fees
5 Jan - 6 January 2025
Omni La Mansion del Rio
Plaza San Antonio Hotel & Spa, Autograph Collection
Pool

Plaza San Antonio Hotel & Spa, Autograph Collection

4.0 star property
9.2 out of 10, Wonderful, (313)
"Excellent accommodations . Friendly and helpful staff. Mr Trinidad was super customer focused. Construction around property wasn’t attractive however our stay was what we needed."
The price is SAR 627
SAR 752 total
includes taxes & fees
29 Dec - 30 Dec
Plaza San Antonio Hotel & Spa, Autograph Collection
The St. Anthony, A Luxury Collection Hotel, San Antonio
Exterior

The St. Anthony, A Luxury Collection Hotel, San Antonio

4.5 star property
8.8 out of 10, Excellent, (1002)
"We were in for a wedding reception, everiwas beautiful and very convenient!"
The price is SAR 795
SAR 940 total
includes taxes & fees
2 Jan - 3 January 2025
The St. Anthony, A Luxury Collection Hotel, San Antonio
AC Hotel by Marriott San Antonio Riverwalk
Exterior

AC Hotel by Marriott San Antonio Riverwalk

4.0 star property
8.8 out of 10, Excellent, (576)
"The room was very nice. Simple, minimalist (which we like) and contemporary. Nice bathroom - LOVED the shower. Great water pressure, hot and had a rainhead and handheld. Problems: We were right next to the elevator and it was LOUD! Granted, the hostess told us and offered a different room, but all other rooms had two queen beds so we chose to keep the king we paid for. Wish we'd switched. Also, the construction (which, again, we were told about in advance) was loud and disruptive in the early...
The price is SAR 418
SAR 494 total
includes taxes & fees
10 Jan - 11 January 2025
AC Hotel by Marriott San Antonio Riverwalk
Canopy by Hilton San Antonio Riverwalk
Exterior

Canopy by Hilton San Antonio Riverwalk

4.0 star property
9.4 out of 10, Exceptional, (1427)
"great location, gorgeous room, friendly helpful staff, and adults only bar! I'll be back. "
The price is SAR 658
SAR 791 total
includes taxes & fees
5 Jan - 6 January 2025
Canopy by Hilton San Antonio Riverwalk
Hyatt Regency San Antonio Riverwalk
Pool

Hyatt Regency San Antonio Riverwalk

4.0 star property
9.0 out of 10, Wonderful, (1668)
"Beautiful accommodations and beautiful view of the river and Christmas lights."
The price is SAR 507
SAR 732 total
includes taxes & fees
20 Jan - 21 January 2025
Hyatt Regency San Antonio Riverwalk
Hilton San Antonio Hill Country
Terrace/patio

Hilton San Antonio Hill Country

4.0 star property
8.2 out of 10, Very Good, (1004)
"A "
The price is SAR 358
SAR 430 total
includes taxes & fees
2 Jan - 3 January 2025
Hilton San Antonio Hill Country
Grand Hyatt San Antonio River Walk
Pool

Grand Hyatt San Antonio River Walk

4.0 star property
9.0 out of 10, Wonderful, (1079)
"Great staff and beautiful room. Price is good for the price."
The price is SAR 635
SAR 762 total
includes taxes & fees
6 Jan - 7 January 2025
Grand Hyatt San Antonio River Walk
Kimpton Santo, an IHG Hotel
Restaurant

Kimpton Santo, an IHG Hotel

4.5 star property
9.4 out of 10, Exceptional, (82)
"The hotel is beautiful and new!, the staff was great although had a bad experience arriving to the hotel on the weekend, was very crowded and one guy from the valet parking was very rude with our uber driver! "
The price is SAR 673
SAR 804 total
includes taxes & fees
2 Jan - 3 January 2025
Kimpton Santo, an IHG Hotel
Hotel Valencia Riverwalk
Exterior

Hotel Valencia Riverwalk

4.5 star property
9.4 out of 10, Exceptional, (1857)
"Beautiful property. On Riverwalk. Staff is outstanding. "
The price is SAR 602
SAR 779 total
includes taxes & fees
5 Jan - 6 January 2025
Hotel Valencia Riverwalk
The Westin Riverwalk, San Antonio
Exterior

The Westin Riverwalk, San Antonio

4.0 star property
8.6 out of 10, Excellent, (1004)
"Great location right on the Riverwalk. Plenty of dining and shopping options available. Nice hotel with friendly staff. I would stay here again!"
The price is SAR 651
SAR 776 total
includes taxes & fees
5 Jan - 6 January 2025
The Westin Riverwalk, San Antonio
Hotel Gibbs Downtown Riverwalk
Front of property

Hotel Gibbs Downtown Riverwalk

4.5 star property
9.0 out of 10, Wonderful, (3253)
"This property was close to everything and right across from the Alamo, the River Walk, Mall, Downtown, and great Restaurants "
The price is SAR 436
SAR 509 total
includes taxes & fees
2 Jan - 3 January 2025
Hotel Gibbs Downtown Riverwalk
Hyatt Regency Hill Country Resort & Spa
Exterior

Hyatt Regency Hill Country Resort & Spa

4.0 star property
8.8 out of 10, Excellent, (1004)
"Always a great stay here. "
The price is SAR 748
SAR 1,112 total
includes taxes & fees
23 Dec - 24 Dec
Hyatt Regency Hill Country Resort & Spa
The Maverick, powered by Placemakr - River Walk
Room

The Maverick, powered by Placemakr - River Walk

4.0 star property
8.6 out of 10, Excellent, (465)
"Two words…Amazing experience!!"
The price is SAR 423
SAR 493 total
includes taxes & fees
6 Jan - 7 January 2025
The Maverick, powered by Placemakr - River Walk
La Cantera Resort & Spa
Property grounds

La Cantera Resort & Spa

4.0 star property
8.8 out of 10, Excellent, (1003)
"Under some renovations but never bothered us we came in for the night to do some Christmas shopping we ate dinner at signature a definite must "
The price is SAR 1,123
SAR 1,482 total
includes taxes & fees
26 Dec - 27 Dec
La Cantera Resort & Spa
Mokara Hotel & Spa San Antonio
Rooftop pool

Mokara Hotel & Spa San Antonio

4.5 star property
9.6 out of 10, Exceptional, (1002)
"Great location and amazing service"
The price is SAR 859
SAR 1,018 total
includes taxes & fees
5 Jan - 6 January 2025
Mokara Hotel & Spa San Antonio
Hilton Palacio Del Rio
Exterior

Hilton Palacio Del Rio

4.0 star property
8.8 out of 10, Excellent, (1003)
"Front entrance and the entire area is under construction/renovation."
The price is SAR 664
SAR 785 total
includes taxes & fees
5 Jan - 6 January 2025
Hilton Palacio Del Rio
The Westin San Antonio North
Outdoor pool

The Westin San Antonio North

4.0 star property
8.4 out of 10, Very Good, (1007)
"It's an older hotel but it still has charm. The staff helpful & inviting made us feel at home. The Christmas decorations and cleanness of the lobby very nice touch. The gym n pool area very clean and well stocked with towels and fresh fruit infused water. Added bonus for my little girl the pool was a heated, which made her day she was able to swim n really enjoy the pool. We would definitely stay here again in the future. "
The price is SAR 312
SAR 374 total
includes taxes & fees
23 Dec - 24 Dec
The Westin San Antonio North
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Medical Center District.
Thompson San Antonio - Riverwalk, by Hyatt

Thompson San Antonio - Riverwalk, by Hyatt

115 Lexington Avenue, San Antonio, TX
The price is SAR 687 per night from Jan 5 to Jan 6
SAR 687
SAR 942 total
includes taxes & fees
5 Jan - 6 January 2025
8.8/10 Excellent! (652 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 4-star hotels in Medical Center District?
Put your suitcase down and relax into your vacation at The Westin San Antonio North. This 4-star hotel is one of Expedia’s travelers’ top picks around Medical Center District.
How much does it cost to stay in a 4-star hotel in Medical Center District?
We can help you quickly find the ideal 4-star hotel for your trip to Medical Center District. Use our handy filter tool to tailor your search by things like budget, amenities and star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from SAR 687

What's the difference between 5-star and 4-star hotels in Medical Center District?
Give yourself the luxury treatment during your Medical Center District escape by choosing a 4-star hotel. As well as featuring upmarket surroundings, these retreats are typically packed with amenities such as large beds, complimentary bathrobes and more. A 5-star hotel will go the extra mile to make your trip an even more lavish and unforgettable one. Concierge assistance, elegant furnishings and world-class dining are a few of the first-rate conveniences and services you’ll likely have access to.
Does Medical Center District have any 4-star all-inclusive resorts?
Finding your dream vacation in Medical Center District is as simple as entering in your destination and dates, and selecting our “All inclusive” filter. Stay and play where just about everything is already taken care of like your accommodations, food and activities, or go for a standard 4-star resort in or around this leading destination.