Find Luxury Hotels in Southern Minnesota, MN
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Southern Minnesota Luxury Hotels
Tonight
Tomorrow
This weekend
Next weekend
Compare Southern Minnesota Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Kahler Grand Hotel
Kahler Grand Hotel
8.2 out of 10, Very Good, (1349)
The price is SAR 608
SAR 700 total
includes taxes & fees
25 Apr - 26 Apr

AmericInn by Wyndham Blue Earth
AmericInn by Wyndham Blue Earth
7.8 out of 10, Good, (413)
The price is SAR 306
SAR 338 total
includes taxes & fees
5 May - 6 May

Med City Inn & Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area
8.0 out of 10, Very Good, (1004)
The price is SAR 300
SAR 346 total
includes taxes & fees
25 Apr - 26 Apr

AmericInn by Wyndham Northfield
AmericInn by Wyndham Northfield
8.4 out of 10, Very Good, (551)
The price is SAR 314
SAR 346 total
includes taxes & fees
14 May - 15 May

Super 8 by Wyndham Jackson MN
Super 8 by Wyndham Jackson MN
8.0 out of 10, Very Good, (518)
The price is SAR 255
SAR 283 total
includes taxes & fees
9 May - 10 May

Coratel Inn & Suites By Jasper Northfield
Coratel Inn & Suites By Jasper Northfield
6.2 out of 10, (576)
The price is SAR 250
SAR 276 total
includes taxes & fees
8 May - 9 May

Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
7.8 out of 10, Good, (1345)
The price is SAR 570
SAR 656 total
includes taxes & fees
27 Apr - 28 Apr

Brentwood Inn & Suites
Brentwood Inn & Suites
8.6 out of 10, Excellent, (1003)
The price is SAR 413
SAR 475 total
includes taxes & fees
25 Apr - 26 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Southern Minnesota
Find out more about Southern Minnesota
Recent reviews of Southern Minnesota hotels
Recent reviews of Southern Minnesota hotels

AmericInn by Wyndham Rochester Near Mayo Clinic
5/5 Excellent
"We had a one night stay. The room was clean and the breakfast was nice."
A verified traveler stayed at AmericInn by Wyndham Rochester Near Mayo Clinic
Posted 1 day ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Find More Hotels near Southern Minnesota
More Hotel Options in Southern Minnesota
- Adults Only Resorts & Hotels in Southern Minnesota
- Adventure Hotels in Southern Minnesota
- Beach Hotels in Southern Minnesota
- Boutique Hotels in Southern Minnesota
- Business Hotels in Southern Minnesota
- Casinos in Southern Minnesota
- Cheap Hotels in Southern Minnesota
- Family Hotels in Southern Minnesota
- Golf Hotels in Southern Minnesota
- Historic Hotels in Southern Minnesota
- Hotel Wedding Venues in Southern Minnesota
- Hotel with a Concierge in Southern Minnesota
- Hotels with Bars in Southern Minnesota
- Hotels with Early Check-in in Southern Minnesota
- Hotels with Free Parking in Southern Minnesota
- Hotels with Hot Tubs in Southern Minnesota
- Hotels with Waterslides in Southern Minnesota
- Hotels with WiFi in Southern Minnesota
- Hotels with a Pool in Southern Minnesota
- Hotels with an Indoor Pool in Southern Minnesota
- Hotels with smoking rooms in Southern Minnesota
- Pet-friendly Hotels in Southern Minnesota
- Resorts & Hotels with Spas in Southern Minnesota
- Romantic Hotels in Southern Minnesota
- Shopping Hotels in Southern Minnesota
- Ski Hotels in Southern Minnesota
- Waterpark Hotels in Southern Minnesota
- Winery Hotels in Southern Minnesota
More Accommodation Types in Southern Minnesota
- Vacation Homes in Minnesota
- Cabin Rentals in Minnesota
- Apartments in Minnesota
- Cottages in Minnesota
- Condo Rentals in Minnesota
- Motels in Minnesota
- Resorts in Minnesota
- Lodges in Minnesota
- Guest Houses in Minnesota
- Aparthotels in Minnesota
- B&B in Minnesota
- Farmstay in Minnesota
- Villas in Minnesota
- RV Parks in Minnesota
- Chalets in Minnesota
- Hostels in Minnesota
- Holiday Park Resorts in Minnesota
Hotels near popular Southern Minnesota Attractions
- Hotels near Mayo Clinic
- Hotels near Mayo Clinic Hospital - Saint Marys Campus
- Hotels near Treasure Island Casino
- Hotels near Mayo Civic Center
- Hotels near Minnesota State University
- Hotels near Mayo Clinic Health System Event Center
- Hotels near Lake Pepin
- Hotels near Apache Mall
- Hotels near Winona State University
- Hotels near Laura Ingalls Wilder Museum
Southern Minnesota Hotels by Star Rating
Explore more hotels
- TownePlace Suites by Marriott Rochester Mayo Clinic Area
- EVEN Hotel Rochester - Mayo Clinic Area by IHG
- The Berkman
- Country Inn & Suites Rochester South Mayo Clinic
- Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
- Aspen Select
- Country Inn & Suites by Radisson, Mankato Hotel and Conference Center, MN
- St James Hotel, a Historic Hotel of America
- AmericInn by Wyndham Mankato Event Center
- Country Inn & Suites by Radisson, Red Wing, MN
- Microtel Inn & Suites by Wyndham Mankato
- AmericInn by Wyndham Winona
- Motel 6 Mankato, MN
- The Plaza Hotel & Suites Winona
- Country Inn & Suites by Radisson, Albert Lea - Austin
- Redwood Lodge
- AmericInn by Wyndham Northfield
- Express Suites Riverport Inn & Suites
- EverSpring Inn & Suites
- Comfort Inn & Suites