The Best Hotels Closest to Mayo Clinic in Rochester for 2025

Compare 427 hotels close to Mayo Clinic with room rates, reviews, and availability. Most hotels are fully refundable.

"Good staff, nice hotell! "

SAR 510 total

includes taxes & fees

7 Feb - 8 Feb

"Walk inside to the other buildings"

SAR 730 total

includes taxes & fees

21 Feb - 22 Feb

"We used the shuttle service to goto Mayo and get back. It was very convenient and timely. The Denny’s was walking distance from the hotel, which was also convenient. The staff were very helpful and friendly. I’m overall we were very happy with our stay."

SAR 423 total

includes taxes & fees

16 Feb - 17 Feb

"This property has a tremendous amount of class. "

SAR 571 total

includes taxes & fees

2 Feb - 3 Feb

"Very clean and neat. Nice to have eating facilities on site. Comfy beds. Window blinds could be black outs."

SAR 452 total

includes taxes & fees

7 Feb - 8 Feb

" The staff was super helpful, I had left something in my room and they called me and are mailing it back to me. Shows they have integrity not only their front staff but housekeeping. Goes along way in my book. We will be staying there again. "

SAR 475 total

includes taxes & fees

15 Feb - 16 Feb

"This place was absolutely beautiful! Super clean and friendly staff. Nice pool and hot tub. Our room was perfect and very clean. We will book it again. We had appointment at ST Mary's Mayo hospital and it was across the street. Very convenient for us. "

SAR 569 total

includes taxes & fees

23 Feb - 24 Feb

"This was a great location that made it really easy for us to check out the area. The staff was friendly and informative. Heater parking was great!"

SAR 528 total

includes taxes & fees

24 Feb - 25 Feb

"Never disappoints!"

SAR 548 total

includes taxes & fees

9 Feb - 10 Feb

"Great service!!"

SAR 309 total

includes taxes & fees

8 Feb - 9 Feb

"We were very comfortable in our room. The location was perfect for us. I had an appointment at Mayo the next morning. Would suggest to change out the shower head. It was limed up and did spray very well. "

SAR 380 total

includes taxes & fees

7 Feb - 8 Feb

"Access and entrance to pool/whirlpool area was far to cold and exposed to elements to actually use on account of weather. Would only be good in summer. Very poor design of hotel. Obviously an after thought"

SAR 437 total

includes taxes & fees

2 Mar - 3 Mar

"The staff were exceptionally friendly and personable. Nice location and nice rooms, no complaints. "

SAR 474 total

includes taxes & fees

8 Feb - 9 Feb

"Crave restaurant on the hotel property got me in without a reservation, great service and food, room was wonderful. Will not hesitate to book another stay. "

SAR 524 total

includes taxes & fees

8 Feb - 9 Feb

"My wife had extensive oral surgery at St Mary’s, and the surgeon asked that we stay in Rochester a few days until he could follow-up. We chose Aspen Suites, and coukd not have been more pleased. Everything about our room and the hotel itself was top notch. The General Manager was excellent, caring, and attentive to my wife’s needs. I give this facility a 10/10 rating "

SAR 703 total

includes taxes & fees

2 Feb - 3 Feb

"This is home away from home. I always stay here because it's convenient underground walking conection with Mayo Clinic specially during Winter.!"

SAR 475 total

includes taxes & fees

7 Feb - 8 Feb

"Our desk clerk at our arrival was amazing. He was efficient, knowledgeable and vey friendly. Our checkout person was also friendly. It’s nice to have an evening soup. "

SAR 368 total

includes taxes & fees

23 Feb - 24 Feb

"The room stayed a bit warmer than I like even though I turned down the temp. The tub was a bit slippery with no guides or handles for assists to get out. "

SAR 382 total

includes taxes & fees

7 Feb - 8 Feb

"7 minutes from Mayo Clinic. Large clean up to date rooms, very nice breakfast! This will be my hotel every time I have appointments at Mayo!"

SAR 243 total

includes taxes & fees

28 Feb - 1 Mar

"Very clean and great location wonderful staff! Will be staying there again"

SAR 552 total

includes taxes & fees

2 Feb - 3 Feb

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Hotels near Other Rochester Attractions

Soldiers Field Veterans Memorial

4.5/5(30 reviews)

You can learn about the history of Rochester with a visit to Soldiers Field Veterans Memorial. Attend a sporting event or simply visit the area's shops.

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Hotels in top Downtown Rochester neighborhoods

Frequently asked questions

What's the area like around Mayo Clinic?

Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 175 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic?

Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hyatt House Rochester/Mayo Clinic Area.

How many hotels will I be able to find near Mayo Clinic?

Expedia has 175 hotels and other accommodations within a mile from Mayo Clinic.

If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?

Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?

For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.

What can I see and do near Mayo Clinic?

You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.

Find hotels near Mayo Clinic, Rochester from SAR 207

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Compare 427 hotels close to Mayo Clinic with room rates, reviews, and availability. Most hotels are fully refundable.

TownePlace Suites by Marriott Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

The Berkman

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel

Hyatt House Rochester/Mayo Clinic Area

Staybridge Suites Rochester - Mayo Clinic Area, an IHG Hotel

Home2 Suites by Hilton Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area South

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Candlewood Suites Rochester Mayo Clinic Area, an IHG Hotel

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Hilton Garden Inn Rochester Downtown, MN

Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel

Aspen Suites

Brentwood Inn & Suites

Hampton Inn Rochester-South

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Quality Inn & Suites Mayo Clinic Area

Aspen Select

Hotels near Other Rochester Attractions

Soldiers Field Veterans Memorial

Shops University Square

University of Minnesota-Rochester

Rochester Art Center

Mayo Civic Center

Rochester Civic Theater

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Hotels near popular Rochester Attractions

Hotels in top Downtown Rochester neighborhoods

Other Hotels near Mayo Clinic, Downtown Rochester

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