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Pick from 67 Southeast Missouri Hotels with WiFi and compare room rates, reviews, and availability. Most hotels are fully refundable.
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
6.6 out of 10, (533)
The price is SAR 195
SAR 216 total
includes taxes & fees
5 Dec - 6 Dec
Microtel Inn & Suites by Wyndham Sainte Genevieve
Microtel Inn & Suites by Wyndham Sainte Genevieve
8.8 out of 10, Excellent, (547)
The price is SAR 314
SAR 345 total
includes taxes & fees
1 Dec - 2 Dec
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
9.4 out of 10, Exceptional, (1059)
The price is SAR 372
SAR 427 total
includes taxes & fees
1 Dec - 2 Dec
Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MO
8.0 out of 10, Very Good, (796)
The price is SAR 189
SAR 211 total
includes taxes & fees
25 Dec - 26 Dec
Town House Inn
Town House Inn
7.8 out of 10, Good, (360)
The price is SAR 198
SAR 212 total
includes taxes & fees
8 Dec - 9 Dec
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
9.6 out of 10, Exceptional, (674)
The price is SAR 412
SAR 457 total
includes taxes & fees
8 Dec - 9 Dec
Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area
6.6 out of 10, (506)
The price is SAR 186
SAR 211 total
includes taxes & fees
5 Dec - 6 Dec
Eagle Inn Charleston
Eagle Inn Charleston
6.8 out of 10, (95)
The price is SAR 260
SAR 289 total
includes taxes & fees
26 Nov - 27 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Southeast Missouri
Find out more about Southeast Missouri
Recent reviews of Southeast Missouri hotels
Recent reviews of Southeast Missouri hotels
5/5 Excellent
"Spotless….blessedly quiet!"
A verified traveler stayed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Posted 12 hours ago
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- Winery Hotels in Southeast Missouri
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Hotels near popular Southeast Missouri Attractions
- Hotels near Southeast Missouri State University
- Hotels near Elephant Rocks State Park
- Hotels near Johnson's Shut-ins State Park
- Hotels near Echo Bluff State Park
- Hotels near Lake Wappapello
- Hotels near Century Casino Caruthersville
- Hotels near Isle Casino Cape Girardeau
- Hotels near Ozark National Scenic Riverways
- Hotels near Big Spring
- Hotels near Taum Sauk Mountain State Park
Southeast Missouri Hotels by Star Rating
Explore more hotels
- Pear Tree Inn Sikeston
- Silo Farm Haus- located in the heart of wine country!
- Drury Plaza Hotel Cape Girardeau Conference Center
- Drury Inn & Suites Sikeston, MO
- Days Inn and Suites by Wyndham Sikeston
- Fairfield Inn & Suites by Marriott Poplar Bluff
- Holiday Inn Express & Suites Perryville, an IHG Hotel
- The Farmstead Hotel
- Courtyard by Marriott Cape Girardeau Downtown
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Hampton Inn Cape Girardeau I 55 East
- Drury Inn & Suites Poplar Bluff
- New Orleans Inn Portageville
- Best Western Plus Sikeston
- Comfort Inn Poplar Bluff North
- Comfort Inn Festus - St Louis South
- Hampton Inn Poplar Bluff
- Super 8 by Wyndham Perryville
- Quality Inn
- Drury Inn & Suites Hayti Caruthersville