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Compare 164 Vacation Homes in Panacea with updated reviews, rates, and availability.

Pet friendly Kayak with the manatees

2.0 star property
9.6 out of 10, Exceptional, (7)
"Great location for us. Place was nice and quiet. Awesome back patio and area for our dog. "
The price is SAR 507
SAR 988 total
includes taxes & fees
6 Jan - 7 Jan
Pet friendly Kayak with the manatees

Happy Shack BEACH & BAY! Kayak, paddle boards, firepit, tiki hut, grille, wifi

10.0 out of 10, Exceptional, (210)
"We fished, swam, played, watched movies, cooked in the well-appointed kitchen and just generally had the best week in the Happy Shack. The bay beach was a surprisingly awesome amenity."
Happy Shack BEACH & BAY! Kayak, paddle boards, firepit, tiki hut, grille, wifi

Dragonfly on the Canal

2.0 star property
10.0 out of 10, Exceptional, (10)
"Great overnight stay. Everyone loved the house. The only thing is I wish we had more time to enjoy it."
The price is SAR 582
SAR 1,315 total
includes taxes & fees
6 Jan - 7 Jan
Dragonfly on the Canal

Oceanfront on a Private Beach-Hot Tub-Beautifully Remodeled-Dog Friendly Beach

10.0 out of 10, Exceptional, (12)
"Our vacation was great! Melynda was amazing! She was great at communicating with us and the house has just about everything you need. Because of a hurricane, we had to leave our prior vacation spot and she was so generous in letting us come to the house one day early! We loved the house being on the beach and seeing dolphins everyday. Our kids loved all the extra things like the boogie boards, all the fishing supplies, the swings under the house, the games in the cabinet, and the hot tub. It was...
Oceanfront on a Private Beach-Hot Tub-Beautifully Remodeled-Dog Friendly Beach

Stay at Panacea Palms, a charming 3/2 less than 1 mile from local boat ramp!!

Stay at Panacea Palms, a charming 3/2 less than 1 mile from local boat ramp!!

AWESOME VIEW... On Private Gulf of Mexico Beach... Majestic Views 🐢🌴🌞

10.0 out of 10, Exceptional, (68)
"Great place for our family to connect. Everything we needed, nice location on the beach. Close enough to seafood restaurants, golf in Wakulla, and other local activities. Highly recommend!"
AWESOME VIEW... On Private Gulf of Mexico Beach... Majestic Views 🐢🌴🌞

LAKE, BEACH, MARINA, FISHING, NATURE HIKING, THIS HOME HAS IT ALL!

10.0 out of 10, Exceptional, (8)
"This is our second time staying in this house and we look forward to coming here every year. Laura, the property manager, is great about communication and is always very helpful. The house is always clean and has everything we need for a great family vacation. We will definitely be back!"
LAKE, BEACH, MARINA, FISHING, NATURE HIKING, THIS HOME HAS IT ALL!

Waterfront Home: Spectacular On-Site Fishing!

9.4 out of 10, Exceptional, (20)
"We enjoyed our stay immensely - the property is perfectly appointed with every amenity you can possibly need, and we especially enjoyed fishing and relaxing in the downstairs sitting area by the fire pit. We already made a reservation to come back in the spring!"
Waterfront Home: Spectacular On-Site Fishing!

Unique Beach Front gathering spot for family, friends and PUPs.

10.0 out of 10, Exceptional, (25)
"Sunrises and sunsets were absolutely stunning!! "
Unique Beach Front gathering spot for family, friends and PUPs.

Blue Seahorse *Carrabelle/Eastpoint/St. George FL Beachfront* Pet-Friendly**

9.8 out of 10, Exceptional, (37)
"Wonderful property and fantastic team managing our stay. Super comfortable and very clean. Great communication and wonderful people."
Blue Seahorse *Carrabelle/Eastpoint/St. George FL Beachfront* Pet-Friendly**

Waterfront Gulf Coast Getaway w/ Boat Dock!

9.0 out of 10, Wonderful, (17)
"We had a wonderful time for the holiday weekend. Everything we needed was provided. We will be booking again! "
Waterfront Gulf Coast Getaway w/ Boat Dock!

Waterfront Escape w/ Balcony on Shell Point Beach!

10.0 out of 10, Exceptional, (29)
"This was our second time at this rental. come Spring we will be back at least two more times. "
Waterfront Escape w/ Balcony on Shell Point Beach!

Johnnie's Getaway - 5 Bedroom with bay view

8.6 out of 10, Excellent, (4)
"Plenty of parking for multiple boats. Quiet property. Only drawback this time of year is the deer flies. Bring lots and lots of 45 % deet spray."
Johnnie's Getaway - 5 Bedroom with bay view

"Bayside Retreat" in Panacea FL.-Bay Front, Dock, 2 Large Porches, WiFi, No Pets

9.8 out of 10, Exceptional, (116)
"Property is amazing! Host Deb is fantastic and you can tell she really cares about her guests. We booked this place to spend Thanksgiving w our daughter who goes to FSU. Can not say enough about how beautiful the place and view. We also rented a boat so having the private dock was fantastic. Kitchen is very well stocked, had everything we needed for a Thanksgiving feast. We did bring big disposable aluminum trays for the turkey and pie plates. Everything else is there, even carving...
"Bayside Retreat" in Panacea FL.-Bay Front, Dock, 2 Large Porches, WiFi, No Pets

New modern home, 3 minute walk to the beach, on bike trail, full RV hookup

10.0 out of 10, Exceptional, (11)
"Fantastic property! We had such a nice stay at Face in the Wind. Beautifully decorated and well stocked with everything you need. Great communication. We loved Face in the Wind!"
New modern home, 3 minute walk to the beach, on bike trail, full RV hookup

River front, less than 5 miles to the gulf, private dock & boat launch!

9.8 out of 10, Exceptional, (9)
"Beautiful and very clean…We had very good prompt communication when needed…We brought our boat and had a fantastic time..We will be booking again!"
River front, less than 5 miles to the gulf, private dock & boat launch!

Timber and Tides

9.6 out of 10, Exceptional, (15)
"We spent the weekend here celebrating my daughter's graduation from FSU. Perfect location and everything about the house was great. I would definitely stay hepp"
Timber and Tides

Gulf to Bay, on the beach home with bay access

10.0 out of 10, Exceptional, (10)
"Nothing beats beachfront! We loved sitting on the screened porch, cooking in the big kitchen, and letting the kids play under the house. We will be back!"
Gulf to Bay, on the beach home with bay access

Wakulla River Retreat - a nature lover’s paradise

10.0 out of 10, Exceptional, (27)
"Second time staying here and I'll book here from now on. Perfect in all ways but for it is 35 minutes from FSU which is both a good thing and a bad thing. Clean, in a tranquil area, right next to the river, nicely decorated, and the owner has thought of everything. It was my son's graduation, and she left goodies and a balloon and graduation cup. Super thoughtful!"
Wakulla River Retreat - a nature lover’s paradise

Leave your WORRIES at Lou's Place!

9.2 out of 10, Wonderful, (7)
"The owner was terrific, helped us tremendously when our boat trailer needed repair. He hooked us up with a great repairman. See Jaime for your stay and book a charter with him, too. We will be back. Loved Carabelle. Great fishing and will book with Cole's Lodge again!"
The price is SAR 394
SAR 635 total
includes taxes & fees
3 Feb - 4 Feb
Leave your WORRIES at Lou's Place!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Panacea

Best deal at Alligator Point

9.6 out of 10, Exceptional, (107)
"I spent a peaceful, beautiful month in this special spot. Every day was gazing at wildlife from the deck or the big picture windows, overlooking the lagoon. Most every night was a picture perfect sunset. Within an hour, and right next door, are many state parks and wildlife refuges. The house was well furnished, great wifi, and very safe. There are many unique towns nearby to explore. Thanks so much to the owner for sharing this beautiful spot."
Best deal at Alligator Point

AWESOME VIEW... On Private Gulf of Mexico Beach... Majestic Views 🐢🌴🌞

10.0 out of 10, Exceptional, (68)
"Great place for our family to connect. Everything we needed, nice location on the beach. Close enough to seafood restaurants, golf in Wakulla, and other local activities. Highly recommend!"
AWESOME VIEW... On Private Gulf of Mexico Beach... Majestic Views 🐢🌴🌞

Waterfront Home: Spectacular On-Site Fishing!

9.4 out of 10, Exceptional, (20)
"We enjoyed our stay immensely - the property is perfectly appointed with every amenity you can possibly need, and we especially enjoyed fishing and relaxing in the downstairs sitting area by the fire pit. We already made a reservation to come back in the spring!"
Waterfront Home: Spectacular On-Site Fishing!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.