Find hotels in Panacea, FL from SAR 321

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Compare 473 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

The Lodge at Wakulla Springs

3.0 star property
9.2 out of 10, Wonderful, (885)
"I had a terrific stay at the lodge. My room was clean and comfortable. The grounds were beautiful and it was so nice to walk around after dinner. Meals at the restaurant were delicious. And best of all was the boat ride to see the wildlife along the river."
The price is SAR 447
SAR 498 total
includes taxes & fees
21 Apr - 22 Apr
The Lodge at Wakulla Springs

Magnuson Hotel Wildwood Inn

3.0 star property
8.6 out of 10, Excellent, (1006)
"The young lady that was cleaning the rooms did a great job and she was friendly. "
The price is SAR 459
SAR 527 total
includes taxes & fees
11 May - 12 May
Magnuson Hotel Wildwood Inn

The Panacea Motel

2.0 star property
9.0 out of 10, Wonderful, (72)
"Cute little vintage motel for overnight stay. Quiet,clean and cozy. Not much to do in the area but we knew that before we booked which is why we chose it for the night."
The price is SAR 513
SAR 571 total
includes taxes & fees
13 Apr - 14 Apr
The Panacea Motel

Best Western Wakulla Inn & Suites

2.5 star property
8.8 out of 10, Excellent, (882)
"We had a very comfortable stay. All staff was friendly and helpful. Room was clean and beds were amazing. Breakfast was tweaked each day with a good variety."
The price is SAR 435
SAR 486 total
includes taxes & fees
27 Apr - 28 Apr
Best Western Wakulla Inn & Suites

The Moorings Hotel and Marina

2.5 star property
8.4 out of 10, Very Good, (27)
"We enjoyed our stay but would appreciate better quality towels. "
The price is SAR 598
SAR 661 total
includes taxes & fees
28 Apr - 29 Apr
The Moorings Hotel and Marina

St James Bay Golf & Pickleball Resort

3.5 star property
9.0 out of 10, Wonderful, (329)
"love st james bay ! "
The price is SAR 548
SAR 606 total
includes taxes & fees
12 Apr - 13 Apr
St James Bay Golf & Pickleball Resort

Franklin Inn

2.0 star property
7.8 out of 10, Good, (379)
"This is a 2-star motel, in a rather remote section of the country. The room was clean. The man at the desk was very pleasant and helpful, and the place was quiet. "
The price is SAR 321
SAR 355 total
includes taxes & fees
27 Apr - 28 Apr
Franklin Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Panacea

Experience relaxing Panacea: its beaches, fishing, natural setting, and more!

Frequently asked questions

Where is the best place to stay in Panacea?

Expedia customers give high marks to The Panacea Motel. See all available top hotels, or vacation rentals in Panacea.

What's the top vacation rental in Panacea?

5 Bedroom Beach house 🏝 Private Beach 🏖 Sleeps 12 🎣 Fishing ☀️Screened porch: Visitors give good reviews to this Panacea vacation home rental, which is located on the beach and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games. Other favorite homes for rent in Panacea are BEACHFRONT! 1 acre PRIVACY! Million Dollar view from EVERY Room! and 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front. See all vacation rentals in Panacea.

If I need to cancel my hotel reservation in Panacea, will I receive a refund?

Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.

Where can I learn more about changing or cancelling my trip to Panacea?

For more details about changing or cancelling your trip to Panacea, click here.

What's the best pet-friendly place to stay in Panacea?

The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.

What are some accommodations with pools in Panacea?
What's the best hotel for staying near Tallahassee Regional Airport (TLH)?

Tallahassee Sun & Moon is one of the top choices for your stay and is a popular property, featuring free WiFi and free parking. It's located 3.5 mi (5.7 km) from Tallahassee Regional Airport. Other options close to the airport include Hampton Inn & Suites Tallahassee Capitol-University and Governors Inn.

What's it like to stay in Panacea?

Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 191 hotels and other accommodations to choose from. Find out more about Panacea.

What are the top places to visit in Panacea?

Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach, and Bald Point State Park. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are USS Mohawk CGC Veterans Memorial Reef and Wilson Beach. Check out what more to see and do in Expedia's Panacea guide.

What's the seasonal weather like in Panacea?

The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.