Find hotels in Panacea, FL from SAR 321
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Compare 473 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

The Lodge at Wakulla Springs
The Lodge at Wakulla Springs
9.2 out of 10, Wonderful, (885)
The price is SAR 447
SAR 498 total
includes taxes & fees
21 Apr - 22 Apr

Magnuson Hotel Wildwood Inn
Magnuson Hotel Wildwood Inn
8.6 out of 10, Excellent, (1006)
The price is SAR 459
SAR 527 total
includes taxes & fees
11 May - 12 May

The Panacea Motel
The Panacea Motel
9.0 out of 10, Wonderful, (72)
The price is SAR 513
SAR 571 total
includes taxes & fees
13 Apr - 14 Apr

Best Western Wakulla Inn & Suites
Best Western Wakulla Inn & Suites
8.8 out of 10, Excellent, (882)
The price is SAR 435
SAR 486 total
includes taxes & fees
27 Apr - 28 Apr

The Moorings Hotel and Marina
The Moorings Hotel and Marina
8.4 out of 10, Very Good, (27)
The price is SAR 598
SAR 661 total
includes taxes & fees
28 Apr - 29 Apr

St James Bay Golf & Pickleball Resort
St James Bay Golf & Pickleball Resort
9.0 out of 10, Wonderful, (329)
The price is SAR 548
SAR 606 total
includes taxes & fees
12 Apr - 13 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Panacea
Experience relaxing Panacea: its beaches, fishing, natural setting, and more!

More cheap stays in Panacea
More cheap stays in Panacea

Best Western Wakulla Inn & Suites
3292 Coastal Hwy 98, Crawfordville, FL
The price is SAR 435 per night from Apr 27 to Apr 28
SAR 435
SAR 486 total
includes taxes & fees
27 Apr - 28 Apr
8.6/10 Excellent! (881 reviews)
Hotels in Panacea with star-rating
Hotels in Panacea with star-rating

3 Star Hotels
38 properties

2 Star Hotels
30 properties
Stay near popular Panacea attractions
Stay near popular Panacea attractions

Bald Point State Park
4.5/5(6 reviews)
You can take time to visit Bald Point State Park during your travels to Alligator Point. Stroll along the beaches in this family-friendly area, or seek out the fishing spots.
USS Mohawk CGC Veterans Memorial Reef
You can find out about the history of Panacea with a visit to USS Mohawk CGC Veterans Memorial Reef. Wander around the natural setting in this relaxing area, or simply enjoy its seafood restaurants.
Recent reviews of Panacea hotels
Recent reviews of Panacea hotels

Secluded Florida Beach Bungalow
5/5 Excellent
Spring 2025
"Wonderful! The cottage had everything we needed. Convenient short walk to the beach, close to state parks. We enjoyed our relaxing stay. "
A verified traveler stayed at Secluded Florida Beach Bungalow
Posted 5 days ago
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Stay near popular Panacea attractions
- Hotels near Bald Point State Park
- Hotels near USS Mohawk CGC Veterans Memorial Reef
- Hotels near Wakulla Springs State Park
- Hotels near St. Marks National Wildlife Refuge
- Hotels near St. Marks Lighthouse
- Hotels near St. James Bay Golf Club
- Hotels near Ochlockonee River State Park
- Hotels near Apalachicola National Forest
- Hotels near Crooked River Lighthouse
Hotels near Panacea Airports
Panacea Hotels by Brand
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Explore more hotels
- PRIVATE LUXURY BEACHFRONT HOME!
- BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.
- Best deal at Alligator Point
- Hideaway Beach Cottage on waterfront with amazing views.
- Cottage on the Bay
- Marsh Beauty
- Gorgeous Ocean Views in Modern Beachfront Home
- Breezy Home w/ Grills, Pool & Beach Access!
- Beach Getaway Just Refreshed, Sleeps 8 <4 br> EV level 2 charging- views
- Beachfront bungalow with private direct beach access. Sleeps 8. Pet friendly!
- Waterfront Panacea Vacation Rental w/ Boat Dock!
- Waters Edge Beachfront Private Residence - Ground Level Home