Photo by Amber Palmer

Find hotels near Mayo Clinic Florida, Jacksonville from SAR 453

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Compare 1,833 hotels close to Mayo Clinic Florida with room rates, reviews, and availability. Most hotels are fully refundable.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
9.4 out of 10, Exceptional, (341)
"Quick easy checkin"
The price is SAR 739
SAR 839 total
includes taxes & fees
23 Mar - 24 Mar
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 star property
9.0 out of 10, Wonderful, (1000)
"convient to shopping"
The price is SAR 459
SAR 521 total
includes taxes & fees
17 Mar - 18 Mar
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 star property
8.4 out of 10, Very Good, (1002)
"."
The price is SAR 497
SAR 564 total
includes taxes & fees
23 Feb - 24 Feb
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Salt Air Inn & Suites

2.5 star property
9.8 out of 10, Exceptional, (285)
"My first impression was how cute & clean everything was! The check in process was smooth and everyone has been so friendly. Very close to restaurants and beach. It is off of a main road so maybe bring earplugs if you’re a light sleeper but only heard things when a motorcycle zoomed by, overall, quiet. "
The price is SAR 528
SAR 599 total
includes taxes & fees
26 Feb - 27 Feb
Salt Air Inn & Suites

Element Jacksonville Beach

3.0 star property
9.6 out of 10, Exceptional, (448)
"Great experience "
The price is SAR 570
SAR 647 total
includes taxes & fees
23 Mar - 24 Mar
Element Jacksonville Beach

The Hotel Palms

3.5 star property
9.6 out of 10, Exceptional, (281)
"Relaxing and calm "
The price is SAR 671
SAR 762 total
includes taxes & fees
23 Feb - 24 Feb
The Hotel Palms

AC Hotel Jacksonville St Johns Town Center

2.5 star property
9.6 out of 10, Exceptional, (80)
"We had a great stay! Really love this hotel and its ambiance. A lot of options for shopping and food. "
The price is SAR 671
SAR 762 total
includes taxes & fees
23 Feb - 24 Feb
AC Hotel Jacksonville St Johns Town Center

The Lodge and Club at Ponte Vedra Beach

5.0 star property
9.4 out of 10, Exceptional, (654)
"10 very clean and family friendly"
The price is SAR 1,872
SAR 2,196 total
includes taxes & fees
2 Mar - 3 Mar
The Lodge and Club at Ponte Vedra Beach

Holiday Inn Express Jacksonville Beach by IHG

2.5 star property
9.2 out of 10, Wonderful, (1001)
"Liked under counter lighting in bathroom"
The price is SAR 521
SAR 592 total
includes taxes & fees
2 Mar - 3 Mar
Holiday Inn Express Jacksonville Beach by IHG

Hampton Inn Jacksonville Beach/Oceanfront

3.0 star property
9.2 out of 10, Wonderful, (2042)
"Breakfast was fantastic. Rooms were clean and nice. Employees were kind and very helpful."
The price is SAR 643
SAR 730 total
includes taxes & fees
27 Feb - 28 Feb
Hampton Inn Jacksonville Beach/Oceanfront

Tru By Hilton Jacksonville St Johns Town Center

2.5 star property
9.2 out of 10, Wonderful, (680)
"Great stay easy checkin"
The price is SAR 525
SAR 596 total
includes taxes & fees
23 Feb - 24 Feb
Tru By Hilton Jacksonville St Johns Town Center

Four Points by Sheraton Jacksonville Beachfront

3.0 star property
9.0 out of 10, Wonderful, (999)
"Great stay everyone was first class"
The price is SAR 889
SAR 1,009 total
includes taxes & fees
26 Feb - 27 Feb
Four Points by Sheraton Jacksonville Beachfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

4.0 star property
9.0 out of 10, Wonderful, (411)
"Loved the hotel and it’s location but the bed was extremely uncomfortable and the only parking option was valet parking."
The price is SAR 690
SAR 783 total
includes taxes & fees
24 Feb - 25 Feb
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Margaritaville Jacksonville Beach

2.5 star property
9.0 out of 10, Wonderful, (2817)
"Great location , near lots of places to eat as the 2 restaurants at the hotel have the same menu! that was the only negative and also the restaurant felt like cafeteria style- no atmosphere. "
The price is SAR 578
SAR 656 total
includes taxes & fees
23 Feb - 24 Feb
Margaritaville Jacksonville Beach

Sheraton Jacksonville Hotel

4.0 star property
9.2 out of 10, Wonderful, (1000)
"Very nice. Will stay again if we're nearby"
The price is SAR 537
SAR 610 total
includes taxes & fees
23 Feb - 24 Feb
Sheraton Jacksonville Hotel

Hotel Indigo Jacksonville-Deerwood Park by IHG

3.5 star property
9.2 out of 10, Wonderful, (1003)
"Everything was great "
The price is SAR 540
SAR 613 total
includes taxes & fees
27 Feb - 28 Feb
Hotel Indigo Jacksonville-Deerwood Park by IHG

Hampton Inn & Suites Jacksonville Deerwood Park

2.5 star property
9.2 out of 10, Wonderful, (1003)
"It was clean and the staff was very friendly. "
The price is SAR 453
SAR 514 total
includes taxes & fees
27 Feb - 28 Feb
Hampton Inn & Suites Jacksonville Deerwood Park

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

3.0 star property
9.0 out of 10, Wonderful, (1001)
"Great! "
The price is SAR 730
SAR 814 total
includes taxes & fees
3 Mar - 4 Mar
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Best Western Oceanfront

2.5 star property
8.8 out of 10, Excellent, (1004)
"Close to pier, right on beach with lots of nearby restaurants. Nice boardwalk. Great breakfast "
The price is SAR 528
SAR 599 total
includes taxes & fees
4 Mar - 5 Mar
Best Western Oceanfront

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

2.5 star property
8.6 out of 10, Excellent, (1000)
"Staff very accommodating!"
The price is SAR 509
SAR 577 total
includes taxes & fees
26 Feb - 27 Feb
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Mayo Clinic Florida
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 34 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Another good choice is Residence Inn By Marriott Jacksonville - Mayo Clinic Area, located just 0.7 mi (1.1 km) away.

How many hotels will I find near Mayo Clinic Florida?

Expedia has 34 hotels and other accommodations within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Players by the Sea and Wilson Center For the Arts. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.