Find Resorts & Hotels with Spas in Key Largo, FL

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Check availability on Key Largo Resorts & Hotels with Spas

Compare Key Largo Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Reefhouse Resort & Marina

3.5 star property
9.2 out of 10, Wonderful, (1336)
"Reefhouse was an excellent choice for our stay in the Keys. A wonderful experience and the staff was top-notch. Will definitely be returning there!"
The price is SAR 1,122
SAR 1,412 total
includes taxes & fees
7 Apr - 8 Apr
Reefhouse Resort & Marina

Playa Largo Resort & Spa, Autograph Collection

4.5 star property
9.0 out of 10, Wonderful, (1001)
"It was a Great place."
The price is SAR 1,497
SAR 1,891 total
includes taxes & fees
20 Apr - 21 Apr
Playa Largo Resort & Spa, Autograph Collection

Kona Kai Resort and Gallery - Adults Only

2.5 star property
9.8 out of 10, Exceptional, (231)
"Kona Kai was EXACTLY the vacation we needed. Everything was lovely,. Sunset kayaking and hot tub to follow, can’t get better than that. We loved grilling in the outdoor charcoal bbqs for dinner. Can’t wait to come visit again! "
Kona Kai Resort and Gallery - Adults Only

Largo Resort

3.0 star property
9.6 out of 10, Exceptional, (280)
"The property absolutely meets its target as a unique, relaxing oasis within meters of US Highway 1. As well, the manager and staff match this with attentive but unobtrusive service. Highly recommended, especially for travelers looking for an experience distinct from the corporate resorts."
The price is SAR 1,399
SAR 1,574 total
includes taxes & fees
1 Apr - 2 Apr
Largo Resort

Gilbert's Resort

2.0 star property
8.6 out of 10, Excellent, (1002)
"We love stopping at Gilbert's for a Rum Runner as we enter the Keys and decided to stay before traveling to our final destination. The rooms were clean, and we enjoyed our stay. "
The price is SAR 1,084
SAR 1,220 total
includes taxes & fees
27 Mar - 28 Mar
Gilbert's Resort

Amoray Dive Resort

2.0 star property
9.0 out of 10, Wonderful, (1012)
"We stumbled upon this resort last minute and really glad we did. Wonderful location, beautiful property, spacious rooms, and helpful staff. I would stay here again."
The price is SAR 807
SAR 908 total
includes taxes & fees
20 Apr - 21 Apr
Amoray Dive Resort

Bayside Inn Key Largo

3.0 star property
8.6 out of 10, Excellent, (1475)
"The pool was very cool "
The price is SAR 784
SAR 976 total
includes taxes & fees
7 Apr - 8 Apr
Bayside Inn Key Largo

Dolphin Point Villas

3.5 star property
9.6 out of 10, Exceptional, (420)
"I visited this place with my wife and 2 kids. The place was awesome, rooms were very clean, well organized, and had everything. The check-in and check-out process was super simple. The bay view is too good. I highly recommend this property. Some minor issues: There were no complimentary water bottles kept in the room and it's very dark outside the rooms to even take a stroll during evening times. But our overall experience was toooooo good."
The price is SAR 1,497
SAR 1,684 total
includes taxes & fees
30 Mar - 31 Mar
Dolphin Point Villas

Courtyard by Marriott Key Largo

3.0 star property
8.0 out of 10, Very Good, (1050)
"Everything nice except somewhat misleading offer to include breakfast in stay."
The price is SAR 762
SAR 857 total
includes taxes & fees
3 Apr - 4 Apr
Courtyard by Marriott Key Largo

Sunset Cove Beach Resort

2.5 star property
8.8 out of 10, Excellent, (1036)
"10/10 amazing and the girl at the front desk was so sweet forgot her name but worked on Sunday 04/23/25. I can’t wait to come back here!!!! clean, safe and just amazing "
The price is SAR 683
SAR 768 total
includes taxes & fees
16 Apr - 17 Apr
Sunset Cove Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Key Largo?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the sunsets in Key Largo. Discover the coral reefs and seafood restaurants during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a top beach spa hotel featuring 3 restaurants, a 24-hour fitness center, a hair salon, and a bar. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. Another popular spa hotel in Key Largo is Reefhouse Resort & Marina.
How many spa hotels will I find in Key Largo?
Among Expedia’s 1243 accommodation options in Key Largo, there are 2 spa hotels.
What's there to see and do in Key Largo?
Enjoy Key Largo and visit Everglades National Park, Jimmy Johnson’s Big Chill, and Bluefin Rock Harbor Marina. If you have a bit of extra time while you’re in the area, you might want to check out John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.
What is a Key Largo spa hotel?
Spa hotels in Key Largo provide lodging and have an on-site spa offering services including facials and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.