Find Business Hotels in Downtown Buffalo, NY
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Compare Downtown Buffalo Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Hyatt Regency Buffalo / Hotel and Conference Center
Hyatt Regency Buffalo / Hotel and Conference Center
8.0 out of 10, Very Good, (1315)
The price is SAR 388
SAR 442 total
includes taxes & fees
26 May - 27 May

Hilton Garden Inn Buffalo Downtown
Hilton Garden Inn Buffalo Downtown
8.6 out of 10, Excellent, (1003)
The price is SAR 442
SAR 503 total
includes taxes & fees
26 May - 27 May

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
8.6 out of 10, Excellent, (1004)
The price is SAR 476
SAR 542 total
includes taxes & fees
12 May - 13 May

Curtiss Hotel, Ascend Hotel Collection
Curtiss Hotel, Ascend Hotel Collection
9.2 out of 10, Wonderful, (1001)
The price is SAR 826
SAR 939 total
includes taxes & fees
1 Jun - 2 Jun

Embassy Suites Buffalo
Embassy Suites Buffalo
8.2 out of 10, Very Good, (998)
The price is SAR 634
SAR 722 total
includes taxes & fees
9 May - 10 May

Buffalo Marriott at LECOM HARBORCENTER
Buffalo Marriott at LECOM HARBORCENTER
9.4 out of 10, Exceptional, (820)
The price is SAR 739
SAR 841 total
includes taxes & fees
18 May - 19 May

Hotel at the Lafayette Trademark Collection by Wyndham
Hotel at the Lafayette Trademark Collection by Wyndham
8.6 out of 10, Excellent, (1001)
The price is SAR 558
SAR 635 total
includes taxes & fees
8 May - 9 May

Hampton Inn & Suites Buffalo Downtown
Hampton Inn & Suites Buffalo Downtown
8.8 out of 10, Excellent, (1001)
The price is SAR 602
SAR 685 total
includes taxes & fees
8 May - 9 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Downtown Buffalo
Find out more about Downtown Buffalo
Recent reviews of Downtown Buffalo hotels
Recent reviews of Downtown Buffalo hotels

Seneca Niagara Resort & Casino
5/5 Excellent
"I loved this hotel, I had a great time. I can’t wait to go back again!! The most enjoyable part of my trip was the casino 🤑
I will be back and I will spread the word about this beautiful casino!!"
A verified traveler stayed at Seneca Niagara Resort & Casino
Posted 2 days ago
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More Accommodation Types in
Hotels near popular Buffalo Attractions
- Hotels near Buffalo Niagara Convention Center
- Hotels near Sahlen Field
- Hotels near Canalside
- Hotels near Shea's Performing Arts Center
- Hotels near Niagara Square
- Hotels near Roswell Park Cancer Institute
- Hotels near Buffalo and Erie County Naval and Military Park
- Hotels near University at Buffalo - Downtown Campus
- Hotels near Buffalo General Medical Center
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Downtown Buffalo Hotels by Star Rating
Explore more hotels
- The Mansion On Delaware Ave
- Courtyard Buffalo Downtown / Canalside
- The Westin Buffalo
- Seneca Niagara Resort & Casino
- M Hotel Buffalo
- Comfort Inn The Pointe
- Sleep Inn & Suites Buffalo Airport
- Holiday Inn Express Grand Island - Niagara Falls by IHG
- Buffalo Airport Hotel
- Garden Place Hotel
- Wingate By Wyndham Niagara Falls
- Hyatt Place Niagara Falls
- Hampton Inn Buffalo - Amherst, NY
- Sheraton Niagara Falls
- Cambria Hotel Niagara Falls
- Holiday Inn Express Cheektowaga North East by IHG
- La Quinta Inn & Suites by Wyndham Buffalo Amherst
- Extended Stay America Suites - Buffalo - Airport
- Crowne Plaza Niagara Falls NY Riverside by IHG
- Motel 6 Buffalo, NY - Airport - Williamsville