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Find Resorts & Hotels with Spas in Cape Girardeau, MO

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Pick from 23 Cape Girardeau Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn Cape Girardeau I 55 East
Pool

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (674)
"It's a nice hotel to stay at, clean, convenient, and the staff are very friendly."
The price is SAR 412
SAR 457 total
includes taxes & fees
1 Dec - 2 Dec
Hampton Inn Cape Girardeau I 55 East
Pear Tree Inn Cape Girardeau West
Exterior

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1008)
"Clean room. Great help at the front desk. Continental breakfast is a little lacking."
The price is SAR 270
SAR 305 total
includes taxes & fees
2 Dec - 3 Dec
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Cape Girardeau
Exterior

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (818)
"Clean and bed was comfy! Nice looking hotel and very friendly staff!"
The price is SAR 355
SAR 400 total
includes taxes & fees
1 Dec - 2 Dec
Drury Inn & Suites Cape Girardeau
Auburn Place Hotel And Suites
Indoor pool

Auburn Place Hotel And Suites

2.5 star property
8.8 out of 10, Excellent, (1014)
"I love going here when we visit! The pool is great during down time and the kids love playing the games. They have a good breakfast and are usually pretty friendly "
Auburn Place Hotel And Suites
Drury Plaza Hotel Cape Girardeau Conference Center
Exterior

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1009)
"What a wonderful hotel, great rooms, the bar and restaurant had really good food and drinks. The staff was very helpful and polite. Would stay there again and plan too."
The price is SAR 372
SAR 419 total
includes taxes & fees
1 Dec - 2 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

2.5 star property
9.4 out of 10, Exceptional, (1033)
"It was great. "
The price is SAR 355
SAR 394 total
includes taxes & fees
8 Dec - 9 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Candlewood Suites Cape Girardeau, an IHG Hotel
Exterior

Candlewood Suites Cape Girardeau, an IHG Hotel

2.5 star property
8.2 out of 10, Very Good, (698)
"Best place I have ever stayed"
The price is SAR 333
SAR 391 total
includes taxes & fees
28 Nov - 29 Nov
Candlewood Suites Cape Girardeau, an IHG Hotel
Pear Tree Inn Cape Girardeau Near the Medical Center
Exterior

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1008)
"Great place to stay. Plenty to see"
The price is SAR 220
SAR 248 total
includes taxes & fees
15 Dec - 16 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center
Town House Inn Cape Giradreau
Exterior

Town House Inn Cape Giradreau

2.5 star property
6.0 out of 10, (156)
"It was a room to lay my head at night. Shower didn't work, ceiling paint was peeling and heavy smell of marijuana even though it was a no smoking room!"
The price is SAR 225
SAR 263 total
includes taxes & fees
26 Nov - 27 Nov
Town House Inn Cape Giradreau
3+ acre Home with New Hot Tub: Pool Table, Putt-Putt, 4 miles to Downtown
The front of our Staycation Home. Entrance is on the front porch.

3+ acre Home with New Hot Tub: Pool Table, Putt-Putt, 4 miles to Downtown

9.0 out of 10, Wonderful, (25)
"Amazing property that we simply didn't stay long enough to enjoy in its completeness. Billiards and Putt-Putt on entry, so attractive that we started playing before we even unpacked! I'm very artsy interior, and lots of room and outdoor fire pit, multiple decks, and an in-ground pool. The home is even on the grounds, an event venue. Probably a wonderful combination for them! Would enjoy returning, but for a longer stay will you could enjoy all with the property had to offer! Highly recommend it"
The price is SAR 1,032
SAR 1,437 total
includes taxes & fees
1 Dec - 2 Dec
3+ acre Home with New Hot Tub: Pool Table, Putt-Putt, 4 miles to Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Cape Girardeau?
Treat yourself to some pampering and book a hotel with a spa. Travelers recommend the gourmet restaurants in Cape Girardeau. Enjoy the historical sites and riverfront during your vacation. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Cape Girardeau?
Among Expedia’s 58 accommodation options in Cape Girardeau, there is 1 spa hotel.
What's there to see and do in Cape Girardeau?
Experience all that Cape Girardeau has to offer when you visit Isle Casino Cape Girardeau, Riverfront Bridge Park, and Show Me Center. If you have a bit of extra time while you’re in the area, you might want to check out Cape Splash Family Aquatic Center and Hunter Valley Winery.
What is a Cape Girardeau spa hotel?
Spa hotels in Cape Girardeau have full on-site spas offering services such as massages and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.