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Find Casinos in Cape Girardeau, MO

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Check availability on Cape Girardeau Casinos

Compare Cape Girardeau Casinos room rates, reviews, and availability. Most hotels are fully refundable.

Town House Inn Cape Giradreau

2.5 star property
6.0 out of 10, (178)
"NA"
The price is SAR 236
SAR 276 total
includes taxes & fees
9 Apr - 10 Apr
Town House Inn Cape Giradreau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1003)
"We enjoyed our stay both times on our vacation to New Orleans."
The price is SAR 387
SAR 436 total
includes taxes & fees
4 May - 5 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1003)
"It was small room but was okay "
The price is SAR 253
SAR 286 total
includes taxes & fees
14 Apr - 15 Apr
Pear Tree Inn Cape Girardeau Near the Medical Center

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.2 out of 10, Very Good, (761)
"The only problem we had was parking. Several people parked in the middle of two spots. A truck and trailer were taking up 6 spots and several spots had trailers and work equipment. They told us we could park in the gravel lot beside the hotel. I would think that is where the trailers and big trucks should park."
The price is SAR 308
SAR 368 total
includes taxes & fees
27 Apr - 28 Apr
Candlewood Suites Cape Girardeau by IHG

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1007)
"Everything was amazing..The clerk was super nice, the room was neat and clean how i like..I would stay at this hotel wherever I need a quick get away to relax."
The price is SAR 270
SAR 305 total
includes taxes & fees
15 Apr - 16 Apr
Pear Tree Inn Cape Girardeau West

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (916)
"5 Stars is not enough for all of the staff on duty April 4th, 2025. These folks are a SOLID 11! There was a genuine tornado approaching and they made sure all the lodgers were in safe spaces and appraised of what was going on. There was no hesitation of what to do, where to go and all was calm. Luckily, all was good. Oh yeah the dinner & breakfast was great the place was clean and our room was fantastic. Value was excellent. Allen B."
The price is SAR 355
SAR 400 total
includes taxes & fees
27 Apr - 28 Apr
Drury Inn & Suites Cape Girardeau

Quality Inn

2.5 star property
7.0 out of 10, Good, (562)
"Love it very clean and very quiet love the experience"
The price is SAR 251
SAR 284 total
includes taxes & fees
9 Apr - 10 Apr
Quality Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Searching for casino hotels in Cape Girardeau?
Hoping to win big in Cape Girardeau? You’re in luck, because you’ll find Isle Casino Cape Girardeau here, not to mention lots more to see and do. Visitors enjoy the riverfront, shopping, and dining options.
What's the best hotel for casino gaming in Cape Girardeau?
The Riverview is a top hotel featuring a casino and free WiFi.
How many hotels that are good for gaming can I expect to find in Cape Girardeau?
Hit the casinos and have a good night’s sleep at one of Expedia’s 58 casino hotels in Cape Girardeau.
When should I take my casino trip to Cape Girardeau?
You might spend a lot of your vacation inside, but if you’re planning to venture beyond the casino, taking a look at local weather data can help you. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Cape Girardeau is 59 inches.
What is there to do in Cape Girardeau?
Cape Girardeau is known for its historic sites, offering you opportunities to enjoy the local culture. Some attractions to visit in the area are Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. For more to see and do, you can plan to visit Show Me Center and Hunter Valley Winery.
What are my transportation options for my casino getaway to Cape Girardeau?
Here are some transportation options in Cape Girardeau: You can arrange a flight to the closest airport, which is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), situated 6 mi (9.7 km) from the city center. If you’d like to explore around the area, you may want to rent a car for your trip.