Photo by Skyy

Find Business Hotels in Cape Girardeau, MO

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Compare Cape Girardeau Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel

2.5 star property
9.4 out of 10, Exceptional, (1001)
"Staff was amazing and the suite was very nice and it felt homey."
The price is SAR 372
SAR 420 total
includes taxes & fees
12 Jan - 13 January 2025
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Drury Inn & Suites Cape Girardeau
Exterior

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (845)
"The staff was super friendly. Really good!"
The price is SAR 338
SAR 381 total
includes taxes & fees
10 Jan - 11 January 2025
Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau West
Exterior

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1003)
"Always a great place to stay. "
The price is SAR 240
SAR 271 total
includes taxes & fees
30 Dec - 31 Dec
Pear Tree Inn Cape Girardeau West
Quality Inn
Exterior

Quality Inn

2.5 star property
7.0 out of 10, Good, (523)
"It was quite and clean"
The price is SAR 229
SAR 258 total
includes taxes & fees
24 Dec - 25 Dec
Quality Inn
Candlewood Suites Cape Girardeau, an IHG Hotel
Exterior

Candlewood Suites Cape Girardeau, an IHG Hotel

2.5 star property
8.2 out of 10, Very Good, (708)
"Very spacious room with very comfortable bed."
The price is SAR 248
SAR 300 total
includes taxes & fees
5 Jan - 6 January 2025
Candlewood Suites Cape Girardeau, an IHG Hotel
Drury Plaza Hotel Cape Girardeau Conference Center
Exterior

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1002)
"Really good. My kiddo had a tonsillectomy done at the hospital there and the staff were very helpful. Got us extra yogurts so she could eat etc…. Thank you! "
The price is SAR 372
SAR 419 total
includes taxes & fees
27 Dec - 28 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Hampton Inn Cape Girardeau I 55 East
Pool

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (683)
"Always a nice stay"
The price is SAR 412
SAR 465 total
includes taxes & fees
29 Dec - 30 Dec
Hampton Inn Cape Girardeau I 55 East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Cape Girardeau