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Compare 197 Vacation Homes in St. Charles with updated reviews, rates, and availability.

Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO

10.0 out of 10, Exceptional, (2)
"Very cute. Very clean host very helpful. What a wonderful weekend we had!! "
Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO

Rural Winona Co. Guest House Getaway: Relax and Enjoy the Simple Things in Life

10.0 out of 10, Exceptional, (36)
"Same way everytime nice clean and helpful"
Rural Winona Co. Guest House Getaway: Relax and Enjoy the Simple Things in Life

Century Cottage-PERFECT for Mayo & downtown visitors!

10.0 out of 10, Exceptional, (110)
"My wife, daughter, and I had a great stay at the Century Cottage this past weekend. The house is very conveniently located between downtown Rochester and the Rochester Recreation Center. It was less than a mile walk/drive to the recreation center and a short drive to downtown Rochester. Mary was also very responsive to any messages we sent. All questions were answered within minutes. We would definitely stay here again if we're ever back in the Rochester area."
Century Cottage-PERFECT for Mayo & downtown visitors!

Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown

10.0 out of 10, Exceptional, (32)
"This home was PERFECT for our stay while our elderly parents were having tests done at Mayo. SUPER clean, which is the first thing i look for "
Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown

1 mi. from Mayo Clinic; Cozy, Clean

9.6 out of 10, Exceptional, (89)
"Nice location. Comfortable beds. Overall very accommodating "
1 mi. from Mayo Clinic; Cozy, Clean

NEW Listing - Entertainment for the whole family. Sleeps up to 12.

10.0 out of 10, Exceptional, (2)
"Arrived at 4pm and the house was all ready for us. House was located in q quiet neighborhood. Pictures were an accurate description of the house. Communication with the owner was quick and smooth. House had a great floorplan and you could see from the front room all the way to the kitchen which was great when traveling with a toddler. Extra bonus points for the permanent gate at the top of the stairs. Kitchen was stocked with plenty of everything you would need plus quite the selection of...
NEW Listing - Entertainment for the whole family. Sleeps up to 12.

Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly

9.8 out of 10, Exceptional, (56)
"We had a group of coaches coming to Rochester for a gymnastics event. The house suited our needs perfectly. Great for a larger group of adults staying together. "
Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly

Bluffside cottage with gorgeous river views

10.0 out of 10, Exceptional, (23)
"Perfect hideaway on the river"
Bluffside cottage with gorgeous river views

Fresh space near Mayo Clinic and downtown

9.4 out of 10, Exceptional, (18)
"Very clean property. It was comfortable and cute. The owners were responsive to us and so helpful"
Fresh space near Mayo Clinic and downtown

Magical Nest Hideaway

10.0 out of 10, Exceptional, (111)
"The wild turkeys and deer who greeted us in the morning. "
Magical Nest Hideaway

Luxury Stay/ Theater / Pool Table / Dogs Welcome

2.0 star property
10.0 out of 10, Exceptional, (5)
"We had the most lovely time talking and cooking and reconnecting with old friends. In fact we were so comfortable in this home we ordered in giving us more time to visit and play games. Thank you. Jennie"
Luxury Stay/ Theater / Pool Table / Dogs Welcome

Within walking distance of all the amenities! Bike the trail~ float the river

10.0 out of 10, Exceptional, (10)
"The house was great! Kitchen is well stocked and we felt right at home. We would love to come back again!"
Within walking distance of all the amenities! Bike the trail~ float the river

Family friendly in the peaceful heart of town

10.0 out of 10, Exceptional, (88)
"Beautiful house, close to the lake. Had everything you could need."
Family friendly in the peaceful heart of town

2 Bedroom Apartment, Walk To Mayo, Free Parking

2.0 star property
The price is SAR 375
SAR 903 total
includes taxes & fees
21 Apr - 22 Apr
2 Bedroom Apartment, Walk To Mayo, Free Parking

Warm and cozy property<br>2 miles to Mayo and St. Mary’s. 4 bedrooms, 3 bathrooms.<br>

10.0 out of 10, Exceptional, (23)
"For us, it’s the perfect place to stay while attending medical visits at Mayo Clinic. Nice to come ‘home’, after a busy day, to a place that feels like home and has everything that we need."
Warm and cozy property<br>2 miles to Mayo and St. Mary’s. 4 bedrooms, 3 bathrooms.<br>

The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

10.0 out of 10, Exceptional, (10)
"Ideal for travelers with pets "
The price is SAR 409
SAR 898 total
includes taxes & fees
30 Mar - 31 Mar
The Little House // Stylish & Cozy ~ 2 mi from Mayo Clinic

Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!

10.0 out of 10, Exceptional, (67)
"Beautiful, well styled and clean home with beautiful views! We had many options for activities in the home and in the city, just a mile away. Highly recommended stay for those seeking quiet but beautiful views!Owners were great to work with and provided many recommendations for sight seeing."
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!

Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.

9.8 out of 10, Exceptional, (43)
"This is a wonderful house - great location, very clean, easy access to Mayo Clinic, shopping and restaurants. We will stay again. "
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (72)
"Home was very clean and full of thoughtful details. Most necessary items were available in home. Very comfortable and location was great. Would definitely stay again. Thank you!! "
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.

10.0 out of 10, Exceptional, (3)
"We were in Rochester for appointments at Mayo Clinic. Access to the Clinic was convenient. The house was clean and had everything we needed for our stay. We'll be back in March and plan to stay there again."
The price is SAR 274
SAR 734 total
includes taxes & fees
7 Apr - 8 Apr
Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in St. Charles

The Berkman

3.0 star property
9.6 out of 10, Exceptional, (279)
"I was there for my treatment at the Mayo and I always stay at the Berkman when I go down for my treatment every month. It’s a great place."
The price is SAR 591
SAR 687 total
includes taxes & fees
15 Apr - 16 Apr
The Berkman

Big River Escape Riverside Cabins

3.0 star property
9.0 out of 10, Wonderful, (27)
"Great location. We are here for fishing the river. We would so stay here again! Very nice! River Ratze bar and restaurant was nice! And SO close!"
The price is SAR 404
SAR 426 total
includes taxes & fees
1 Apr - 2 Apr
Big River Escape Riverside Cabins

Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!

10.0 out of 10, Exceptional, (67)
"Beautiful, well styled and clean home with beautiful views! We had many options for activities in the home and in the city, just a mile away. Highly recommended stay for those seeking quiet but beautiful views!Owners were great to work with and provided many recommendations for sight seeing."
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.