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Compare 197 Vacation Homes in St. Charles with updated reviews, rates, and availability.

Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO
Charming 1-bedroom house in delightful Winona with WiFi, AC and PRIVATE PATIO
10.0 out of 10, Exceptional, (2)

Rural Winona Co. Guest House Getaway: Relax and Enjoy the Simple Things in Life
Rural Winona Co. Guest House Getaway: Relax and Enjoy the Simple Things in Life
10.0 out of 10, Exceptional, (36)

Century Cottage-PERFECT for Mayo & downtown visitors!
Century Cottage-PERFECT for Mayo & downtown visitors!
10.0 out of 10, Exceptional, (110)

Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown
Delightful family home near parks, nature center, 1.5 m to Mayo Clinic downtown
10.0 out of 10, Exceptional, (32)

1 mi. from Mayo Clinic; Cozy, Clean
1 mi. from Mayo Clinic; Cozy, Clean
9.6 out of 10, Exceptional, (89)

NEW Listing - Entertainment for the whole family. Sleeps up to 12.
NEW Listing - Entertainment for the whole family. Sleeps up to 12.
10.0 out of 10, Exceptional, (2)

Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly
Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly
9.8 out of 10, Exceptional, (56)

Bluffside cottage with gorgeous river views
Bluffside cottage with gorgeous river views
10.0 out of 10, Exceptional, (23)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in St. Charles

The Berkman
The Berkman
9.6 out of 10, Exceptional, (279)
The price is SAR 591
SAR 687 total
includes taxes & fees
15 Apr - 16 Apr

Big River Escape Riverside Cabins
Big River Escape Riverside Cabins
9.0 out of 10, Wonderful, (27)
The price is SAR 404
SAR 426 total
includes taxes & fees
1 Apr - 2 Apr

Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
10.0 out of 10, Exceptional, (67)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of St. Charles hotels
Recent reviews of St. Charles hotels

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
5/5 Excellent
"Nice hotel "
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Posted 20 hours ago