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Discover 8,742 Serra Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Sycuan Casino Resort
Sycuan Casino Resort
9.2 out of 10, Wonderful, (1157)
The price is SAR 398
SAR 482 total
includes taxes & fees
14 Apr - 15 Apr

Days Inn by Wyndham San Diego-East/El Cajon
Days Inn by Wyndham San Diego-East/El Cajon
7.6 out of 10, Good, (1001)
The price is SAR 319
SAR 351 total
includes taxes & fees
15 Apr - 16 Apr

Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San Diego
8.2 out of 10, Very Good, (1000)
The price is SAR 402
SAR 442 total
includes taxes & fees
20 Apr - 21 Apr

SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake
9.6 out of 10, Exceptional, (292)
The price is SAR 656
SAR 723 total
includes taxes & fees
18 Apr - 19 Apr

Ramada by Wyndham San Diego Poway Miramar
Ramada by Wyndham San Diego Poway Miramar
6.8 out of 10, (757)
The price is SAR 280
SAR 308 total
includes taxes & fees
20 Apr - 21 Apr

Sonesta ES Suites San Diego - Rancho Bernardo
Sonesta ES Suites San Diego - Rancho Bernardo
8.4 out of 10, Very Good, (991)
The price is SAR 390
SAR 440 total
includes taxes & fees
27 Apr - 28 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Serra Mesa
Where to stay in Serra Mesa
Hotels in top San Diego neighborhoods Learn more about Serra Mesa

Downtown San Diego
3 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Recent reviews of Serra Mesa hotels
Recent reviews of Serra Mesa hotels

Best Western Seven Seas
5/5 Excellent
"Lots of plants and grass it’s beautiful"
A verified traveler stayed at Best Western Seven Seas
Posted 3 hours ago
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Serra Mesa Hotels by Star Rating
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