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Discover 8,407 Serra Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Best Western Seven Seas
Pool
Best Western Seven Seas
3.0 star property
7.6 out of 10, Good, (2593)
"It’s our first time to stay in this property and I recommended this. Walking distance to the fashion valley mall which is convenient. The only issue was I wish they have an elevator for the second floor but other than that all is good. Will stay here again in the future."
The price is SAR 351
SAR 389 total
includes taxes & fees
29 Sep - 30 Sep
Best Western Seven Seas
Days Inn by Wyndham San Diego Hotel Circle
Exterior
Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
7.6 out of 10, Good, (1896)
"Very nice."
The price is SAR 348
SAR 385 total
includes taxes & fees
13 Oct - 14 Oct
Days Inn by Wyndham San Diego Hotel Circle
Lafayette Hotel & Club
Lobby
Lafayette Hotel & Club
4.0 star property
9.2 out of 10, Wonderful, (359)
"Every area of the Lafayette is so picturesque from the moment you step foot inside and out. The lobby, the lobby bar, the restaurants, the pool area, the bowling center, the room itself. I will definitely be returning. "
The price is SAR 893
SAR 984 total
includes taxes & fees
30 Sep - 1 Oct
Lafayette Hotel & Club
Holiday Inn Express San Diego Downtown, an IHG Hotel
Exterior
Holiday Inn Express San Diego Downtown, an IHG Hotel
2.5 star property
8.4 out of 10, Very Good, (1116)
"Good hotel, but way overpriced. I understand there was a convention nearby but this hotel was not worth $300+ per night. On top of that they charge $35 per night for parking. Ridiculous."
The price is SAR 539
SAR 597 total
includes taxes & fees
20 Oct - 21 Oct
Holiday Inn Express San Diego Downtown, an IHG Hotel
Hilton San Diego Mission Valley
Exterior
Hilton San Diego Mission Valley
4.0 star property
7.8 out of 10, Good, (1218)
"The property is centrally located and the staff was very nice. It was clean, but seemed like it could use a little TLC, but it was a good value."
The price is SAR 469
SAR 522 total
includes taxes & fees
3 Oct - 4 Oct
Hilton San Diego Mission Valley
DoubleTree by Hilton Hotel San Diego - Mission Valley
Exterior
DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
8.2 out of 10, Very Good, (1028)
"Really nice and quite hotel . "
The price is SAR 597
SAR 651 total
includes taxes & fees
27 Oct - 28 Oct
DoubleTree by Hilton Hotel San Diego - Mission Valley
Marriott Vacation Club®, San Diego
Exterior
Marriott Vacation Club®, San Diego
3.5 star property
9.2 out of 10, Wonderful, (1004)
"Everything was excellent. The bed was comfortable. "
The price is SAR 746
SAR 830 total
includes taxes & fees
20 Oct - 21 Oct
Marriott Vacation Club®, San Diego
Uptown Inn by Vantaggio Suites
Exterior
Uptown Inn by Vantaggio Suites
2.5 star property
7.8 out of 10, Good, (57)
"Very new and freshly renovated room. Nice staff."
The price is SAR 413
SAR 447 total
includes taxes & fees
14 Oct - 15 Oct
Uptown Inn by Vantaggio Suites
Howard Johnson by Wyndham National City/San Diego South
Exterior
Howard Johnson by Wyndham National City/San Diego South
2.0 star property
7.2 out of 10, Good, (1002)
"Cute and very clean"
The price is SAR 284
SAR 308 total
includes taxes & fees
8 Oct - 9 Oct
Howard Johnson by Wyndham National City/San Diego South
Stay Classy Hostel
Front of property
Stay Classy Hostel
2.0 star property
9.4 out of 10, Exceptional, (494)
"Place felt safe, cozy and comfortable"
The price is SAR 238
SAR 258 total
includes taxes & fees
1 Oct - 2 Oct
Stay Classy Hostel
Sonder The Baker
Room
Sonder The Baker
3.5 star property
8.0 out of 10, Very Good, (304)
"Hotel was really cozy and nice. It is on the smaller side, and not very spacious. Really recommend this hotel! "
The price is SAR 513
SAR 558 total
includes taxes & fees
20 Oct - 21 Oct
Sonder The Baker
Courtyard by Marriott San Diego Mission Valley/Hotel Circle
Exterior
Courtyard by Marriott San Diego Mission Valley/Hotel Circle
3.0 star property
8.2 out of 10, Very Good, (1023)
"Perfect for my trip, easy to get to from the airport and allowed early check in without much issues. Overall it was quite and a good experience. "
The price is SAR 507
SAR 564 total
includes taxes & fees
20 Oct - 21 Oct
Courtyard by Marriott San Diego Mission Valley/Hotel Circle
Hilton Garden Inn San Diego Mission Valley Stadium
Exterior
Hilton Garden Inn San Diego Mission Valley Stadium
3.0 star property
8.0 out of 10, Very Good, (1003)
"This was a stay for a one night business trip to San Diego. Everything was fine, really, but the parking was very full when I arrived and the signs weren’t very clear as to what parking was available. The breakfast buffet wasn’t included with the stay and given the rather generic nature of the items available, it should have been. There are more fruits in the world than apples, oranges, and bananas. Overall, it was a pleasant experience, but there was nothing that stood out as remarkable while I...
The price is SAR 523
SAR 580 total
includes taxes & fees
20 Oct - 21 Oct
Hilton Garden Inn San Diego Mission Valley Stadium
San Diego Downtown Lodge
Room
San Diego Downtown Lodge
2.0 star property
6.4 out of 10, (1003)
"Great service "
The price is SAR 263
SAR 341 total
includes taxes & fees
30 Sep - 1 Oct
San Diego Downtown Lodge
Baymont by Wyndham San Diego Downtown
Exterior
Baymont by Wyndham San Diego Downtown
2.5 star property
6.6 out of 10, (1004)
"Better than expected! Clean, nice inside!"
The price is SAR 339
SAR 369 total
includes taxes & fees
8 Oct - 9 Oct
Baymont by Wyndham San Diego Downtown
Studio 6 National City, CA - Naval Base San Diego
Outdoor pool
Studio 6 National City, CA - Naval Base San Diego
2.0 star property
7.2 out of 10, Good, (843)
"Great location for the price. Room felt clean if a little lived in; dent in the fridge and wear on the restroom fixtures. Toilet flush was a little stiff but manageable. Staff was friendly and checking in and out was simple. "
The price is SAR 319
SAR 351 total
includes taxes & fees
14 Oct - 15 Oct
Studio 6 National City, CA - Naval Base San Diego
Mission View Inn & Suites San Diego Sea World - Zoo
Front of property
Mission View Inn & Suites San Diego Sea World - Zoo
2.5 star property
6.0 out of 10, (358)
"My stay was comfortable and quiet, i like the movie channels,, I'm a tv fanatic. "
The price is SAR 417
SAR 459 total
includes taxes & fees
29 Sep - 30 Sep
Mission View Inn & Suites San Diego Sea World - Zoo
Sheraton Mission Valley San Diego Hotel
Pool
Sheraton Mission Valley San Diego Hotel
4.0 star property
8.4 out of 10, Very Good, (1181)
"Friendly staff, rooms clean and spaces didn’t feel like cramped quarters "
The price is SAR 521
SAR 588 total
includes taxes & fees
29 Sep - 30 Sep
Sheraton Mission Valley San Diego Hotel
Ramada by Wyndham San Diego National City
Front of property
Ramada by Wyndham San Diego National City
3.0 star property
6.0 out of 10, (268)
"There was a roach in the bathroom and the hot tub was very murky. The rooms are a bit dated. Our door lock was messed up and it looked like our door had been kicked in at some point. I was still comfortable in the room. The staff was friendly and it looked like it would be a fun part of town."
The price is SAR 402
SAR 443 total
includes taxes & fees
27 Oct - 28 Oct
Ramada by Wyndham San Diego National City
Lamplighter Inn & Suites at SDSU
Lobby
Lamplighter Inn & Suites at SDSU
2.5 star property
9.0 out of 10, Wonderful, (1004)
"My husband and I were pleasantly surprised with the full kitchen in the room (full fridge, stove, microwave and a kitchen sink) with basic kitchen items. We only stayed there one night but we would stay there again. "
The price is SAR 558
SAR 616 total
includes taxes & fees
29 Sep - 30 Sep
Lamplighter Inn & Suites at SDSU
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Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Are you looking for Serra Mesa travel tips? Be sure to check out Escala Dog Park and Civita Dog Park while you're in the neighborhood.

How many hotels will I be able to find in the Serra Mesa area?

Expedia has 31 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.

Where can I learn more about changing or cancelling my trip to Serra Mesa?

For more information about picking new dates or cancelling your trip to Serra Mesa, click here.

What can I see and do in this San Diego neighborhood?

Create some family memories with a visit to Escala Dog Park or Civita Dog Park while you're in Serra Mesa. A visit to Stadium Golf Center & Batting Cages is also worth the trip while you're discovering the neighborhood. A few places to visit in the area around Serra Mesa include Convoy District, Old Cactus Garden, and Snapdragon Stadium. While you're out sightseeing in San Diego, be sure to visit other sights like Centrum Dog Park or Kearny Mesa Dog Park.