Find hotels in Serra Mesa, San Diego from SAR 249

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Discover 8,797 Serra Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Pleasant Inn

2.5 star property
8.4 out of 10, Very Good, (1003)
"Floors could have been cleaner but everything else was very clean. Convenient location and just what I needed."
The price is SAR 331
SAR 379 total
includes taxes & fees
1 May - 2 May
Pleasant Inn

California Suites Hotel

2.0 star property
7.4 out of 10, Good, (1798)
"Very last minute solo booking for family emergency. Picked hotel due to decent location and distance from airport, services, price and that they actually had free parking. Didn’t use pool, but was nice they had one. Everything was just fine and served its purpose for a weekend trip. Room had single queen bed, plenty of closet space if needed it, microwave and mini fridge. "
The price is SAR 334
SAR 376 total
includes taxes & fees
27 Apr - 28 Apr
California Suites Hotel

Town and Country San Diego

4.0 star property
8.6 out of 10, Excellent, (1176)
"The place is 5star. The front desk Vivian doesn’t want yo give the upgrade. She said upgrade is available but with fee and as well of late check out. I got the upgrade bec expedia rep did a refund instead just to get my perks. She said to get late out i have to call them first before checking in"
The price is SAR 790
SAR 992 total
includes taxes & fees
23 May - 24 May
Town and Country San Diego

Best Western Seven Seas

3.0 star property
7.8 out of 10, Good, (2707)
"Wonderful"
The price is SAR 341
SAR 384 total
includes taxes & fees
28 Apr - 29 Apr
Best Western Seven Seas

Lafayette Hotel & Club

4.0 star property
9.2 out of 10, Wonderful, (771)
"so worth it"
The price is SAR 848
SAR 954 total
includes taxes & fees
27 Apr - 28 Apr
Lafayette Hotel & Club

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
7.8 out of 10, Good, (2159)
"Nice staff "
The price is SAR 327
SAR 369 total
includes taxes & fees
27 Apr - 28 Apr
Days Inn by Wyndham San Diego Hotel Circle

Handlery Hotel

3.5 star property
8.0 out of 10, Very Good, (1690)
"It’s ok. Pool area great including the restaurant that serves poolside. A bit old and only provided caffeine free coffee (huh??? Checked housekeeping cart and all caffeine free) Don’t love high parking fee. You won’t be upset.. you won’t be wowed either. But it’s a good safe and nice place to stay. "
The price is SAR 447
SAR 504 total
includes taxes & fees
28 Apr - 29 Apr
Handlery Hotel

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2852)
"Very clean"
The price is SAR 571
SAR 656 total
includes taxes & fees
11 May - 12 May
Legacy Resort Hotel & Spa

The Atwood Hotel San Diego - SeaWorld/Zoo

3.0 star property
7.8 out of 10, Good, (1901)
"Great service from front counter staff "
The price is SAR 402
SAR 453 total
includes taxes & fees
27 Apr - 28 Apr
The Atwood Hotel San Diego - SeaWorld/Zoo

Kings Inn San Diego

2.5 star property
8.8 out of 10, Excellent, (3220)
":)"
The price is SAR 382
SAR 429 total
includes taxes & fees
27 Apr - 28 Apr
Kings Inn San Diego

Mission Bay Inn San Diego

2.5 star property
7.2 out of 10, Good, (1195)
"Location is under construction. Food was not available which that information was given prior to checking in at location "
The price is SAR 317
SAR 365 total
includes taxes & fees
4 May - 5 May
Mission Bay Inn San Diego

Crowne Plaza San Diego - Mission Valley by IHG

3.5 star property
7.4 out of 10, Good, (1002)
"."
The price is SAR 492
SAR 567 total
includes taxes & fees
11 May - 12 May
Crowne Plaza San Diego - Mission Valley by IHG

Motel 6 San Diego, CA - Hotel Circle - Mission Valley

2.0 star property
6.8 out of 10, (1375)
"Good. Prices"
The price is SAR 307
SAR 346 total
includes taxes & fees
28 Apr - 29 Apr
Motel 6 San Diego, CA - Hotel Circle - Mission Valley

San Diego Mission Bay Resort

4.0 star property
8.2 out of 10, Very Good, (1183)
"amazing! we have lots of fun everything was clean we had a beautiful view in the morning & through out the day 10/10 we will be back! "
The price is SAR 672
SAR 942 total
includes taxes & fees
4 May - 5 May
San Diego Mission Bay Resort

SureStay Hotel by Best Western San Diego Pacific Beach

2.5 star property
8.0 out of 10, Very Good, (1035)
"Great place to stay, but could hear the freeway. "
The price is SAR 330
SAR 365 total
includes taxes & fees
30 Apr - 1 May
SureStay Hotel by Best Western San Diego Pacific Beach

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

3.0 star property
8.0 out of 10, Very Good, (1241)
"appreciated the proximity to sights we wanted to see. Although parking was available, space was tight. Didn't always enjoy having to navigate leaving the propertyl."
The price is SAR 411
SAR 464 total
includes taxes & fees
27 Apr - 28 Apr
La Quinta Inn & Suites by Wyndham San Diego Mission Bay

Best Western Plus Hacienda Hotel Old Town

3.0 star property
8.4 out of 10, Very Good, (1591)
"Property was unique and charming. Staff was accommodating. Food was good. Pool was heated and lovely. Staff went above and beyond to make stay it’s best. Only concerning issue is property is very large and challenging physically due to layout. If over 60 make sure you ask for best room location. "
The price is SAR 555
SAR 626 total
includes taxes & fees
27 Apr - 28 Apr
Best Western Plus Hacienda Hotel Old Town

E-Z 8 Motel Old Town

2.5 star property
6.2 out of 10, (2025)
"Love this place "
The price is SAR 249
SAR 280 total
includes taxes & fees
27 Apr - 28 Apr
E-Z 8 Motel Old Town

Old Town Western Inn & Suites

2.5 star property
7.2 out of 10, Good, (1008)
"Nice room. Clean and quiet."
The price is SAR 333
SAR 368 total
includes taxes & fees
28 Apr - 29 Apr
Old Town Western Inn & Suites

Comfort Inn Sea World Area

3.5 star property
8.4 out of 10, Very Good, (2003)
"The hotel is very clean (rooms and faculty overall). Good continental breakfast and friendly staff. Cleanliness to us is very important and this place was great for that. The location is near a lot of shopping areas and an easy drive to main SD points. Immediate neighborhood is not the nicest but if you are driving that is not an issue"
The price is SAR 392
SAR 442 total
includes taxes & fees
27 Apr - 28 Apr
Comfort Inn Sea World Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels will I be able to find in the Serra Mesa area?

Expedia has 37 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.

Where can I learn more about changing or cancelling my trip to Serra Mesa?

For more information about picking new dates or cancelling your trip to Serra Mesa, click here.

What can I see and do in this San Diego neighborhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.