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Find hotels in Santa Ana, Panama City from SAR 92
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Discover 1,406 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

La Manzana by Wynwood House
La Manzana by Wynwood House
7.2 out of 10, Good, (9)
The price is SAR 183
SAR 276 total
includes taxes & fees
12 Mar - 13 Mar

Hostal La Cigarra
Hostal La Cigarra
7.4 out of 10, Good, (44)
The price is SAR 92
SAR 101 total
includes taxes & fees
13 Mar - 14 Mar

Hotel República
Hotel República
6.6 out of 10, (164)
The price is SAR 122
SAR 134 total
includes taxes & fees
13 Mar - 14 Mar

Casa Quijano 06 By Wynwood House
Casa Quijano 06 By Wynwood House
9.0 out of 10, Wonderful, (2)
The price is SAR 207
SAR 331 total
includes taxes & fees
12 Mar - 13 Mar

ART CASCO The Hotel
ART CASCO The Hotel
4.0 out of 10, (2)

Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
8.4 out of 10, Very Good, (2076)
The price is SAR 431
SAR 475 total
includes taxes & fees
4 Apr - 5 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Ana
Where to stay in Santa Ana
Hotels in top Panama City neighborhoods Learn more about Santa Ana

Casco Viejo
4.5/5(178 area reviews)
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.
Recent reviews of Santa Ana hotels
Recent reviews of Santa Ana hotels

Hotel Riu Plaza Panama
5/5 Excellent
"The staff is great! Super nice hotel! Awesome location. Many dining options. We ate by the pool one nite, had sushi one nite, ate at Tastes one night. The 24 hr cafe is awesome. The free breakfast is the most amaxong layout of fodd ive ever seen. Our room was spotless and big! We had a 1 bedroom suite. View from our room was awesome. Tour and ticket assistance awesome! I highly recommend this hotel."
A verified traveler stayed at Hotel Riu Plaza Panama
Posted 9 hours ago
Explore a world of travel with Expedia
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