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Find 5 Star Hotels in Santa Ana from SAR 307

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Check availability on Santa Ana 5 Star Hotels

Compare Santa Ana 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (3598)
"I always enjoy Rui hotels, this one was no different. Staff was nice and accommodating."
The price is SAR 469
SAR 516 total
includes taxes & fees
26 Feb - 27 Feb
Hotel Riu Plaza Panama

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1003)
"Loved it and great service . Will return "
The price is SAR 666
SAR 733 total
includes taxes & fees
28 Feb - 1 Mar
Waldorf Astoria Panama

W Panama

5.0 star property
8.8 out of 10, Excellent, (1002)
"Excellent room."
The price is SAR 597
SAR 657 total
includes taxes & fees
2 Mar - 3 Mar
W Panama

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1002)
"The Hilton has not failed me yet! The hotel was excellent! The location is ideal, good resturants within the hotel as well as surrounding, the pool was nice (a little cold for my liking but a great area), and the room was clean and comfortable. The bed was super comfortable and the room was just a nice place to relax when inside. The water was not super hot but got the job done. The staff was always familiar and helpful and room service was quick and efficient. The area the hotel is in is...
The price is SAR 571
SAR 628 total
includes taxes & fees
1 Mar - 2 Mar
Hilton Panama

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1006)
"It was great hotel. 15 mins to all attractions with Uber. The staff and service were amazing. Great breakfast buffet and other dining options. The furnitures in the rooms were not 5 star quality. There were a lot of kids in the pool area. "
The price is SAR 821
SAR 904 total
includes taxes & fees
1 Mar - 2 Mar
JW Marriott Panama

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1002)
"We stayed here from January 18-22, 2025, and it was a beautiful resort! Our room, #902 on the 9th floor, had a spectacular ocean view with a balcony. The room was spacious, clean, and our king-size bed was incredibly comfortable. The resort offers several restaurants, though not all were open during our stay. We ordered food from Starfish and was quite good. The pool area was beautifully designed, with multiple pools to choose from, making for a relaxing experience. The only downside was the...
The price is SAR 723
SAR 795 total
includes taxes & fees
3 Mar - 4 Mar
The Westin Playa Bonita Panama

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (381)
"A beautiful place and great staff!! "
The price is SAR 1,384
SAR 1,523 total
includes taxes & fees
4 Feb - 5 Feb
Sofitel Legend Casco Viejo, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (542)
"Need more diiner options"
The price is SAR 709
SAR 780 total
includes taxes & fees
21 Feb - 22 Feb
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1001)
"Beautiful hotel with warm and friendly staff. Spacious rooms and very clean. Enjoyed the art program. "
The price is SAR 603
SAR 663 total
includes taxes & fees
1 Mar - 2 Mar
Bristol Panama, a Registry Collection Hotel

Renaissance Panama City Hotel

5.0 star property
8.4 out of 10, Very Good, (5)
"There are no taxis at the hotel it takes 20 minutes for a uber or taxi. Restaurant has a limited menu. Try to order a tuna fish sandwich but the do not have it. "
The price is SAR 446
SAR 491 total
includes taxes & fees
14 Feb - 15 Feb
Renaissance Panama City Hotel

Veneto Hotel & Casino

5.0 star property
6.2 out of 10, (998)
"Actually didn't stay, the hotel is closed and out of business"
Veneto Hotel & Casino
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Frequently asked questions

What are the best 5-star hotels in Santa Ana?
According to reviews by our customers, Villa Palma Boutique Hotel is one of the best properties for an indulgent stay in the Panama City neighborhood of Santa Ana. Want more 5-star hotels around the area? Waldorf Astoria Panama and Hilton Panama will cater to your upscale desires.
How much does it cost to stay in a 5-star hotel in Santa Ana?
The amount you pay for a 5-star hotel in Santa Ana can vary according to when you prefer to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to land the best deal on a high-end getaway.

  • Search for the lowest price per night from SAR 307

What makes a hotel 5 stars in Santa Ana?
From high-end dining venues and 24-hour fitness centers to swimming pools and premium bedding, the 5-star experience in Santa Ana is all about luxury and comfort. But it requires more than just upscale conveniences to receive a 5-star rating. Hotels must also offer superior guest services like in-room massages, laundry and dry cleaning and room service any time day or night.
Are there any 5-star all-inclusive resorts in Santa Ana?
Expedia’s filter tool is the best way to search for exactly what you’re looking for. Select “5-star” and “All inclusive” to show the most luxurious hotels in Santa Ana where your meals, room, entertainment and activities are included in the upfront price. At these getaways, your trip is pure leisure from the moment you put down your suitcase.
What are the top 5-star spa hotels in Santa Ana?
If you’re looking for some TLC, you can’t beat W Panama. Other 5-star spa properties that are renowned for their rejuvenating treatments are Hilton Panama and Waldorf Astoria Panama, also found in or around Santa Ana.
Are there any 5-star vacation rentals in Santa Ana?
Although there aren’t any 5-star vacation rentals in Santa Ana on our site, we have a range of stays that promise a fantastic getaway. Discover one that matches your needs by searching our vacation rentals in Santa Ana.