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Find 5 Star Hotels in Santa Ana from SAR88

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Compare Santa Ana 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Front of property
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (3058)
"I had a nice stay at this hotel. The security was good, making me feel safe throughout my visit. Luis R was very attentive and friendly, and the facilities were well-maintained. The room was clean and comfortable, and I appreciated the added safety features like secure access to the rooms. Overall, a wonderful experience. Central location, short walking distance to the metro station, food and shopping areas. I highly recommend for anyone looking for a secure and comfortable place to stay."
The price is SAR 409
SAR 450 total
includes taxes & fees
14 Oct - 15 Oct
Hotel Riu Plaza Panama
Waldorf Astoria Panama
Room
Waldorf Astoria Panama
5.0 star property
9.0 out of 10, Wonderful, (982)
"The Staff was top notch/they took care of my every need."
The price is SAR 597
SAR 657 total
includes taxes & fees
11 Oct - 12 Oct
Waldorf Astoria Panama
Sofitel Legend Casco Viejo, Panama City
Exterior detail
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, (305)
"Olinka manager the best, good breakfast, delicious mojitos.... the breeze and the view from the pool area was espactaculR"
The price is SAR 1,030
SAR 1,133 total
includes taxes & fees
1 Oct - 2 Oct
Sofitel Legend Casco Viejo, Panama City
JW Marriott Panama
Pool
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1003)
"The hotel was nice the bathrooms in the hotel were very dirty. "
The price is SAR 657
SAR 712 total
includes taxes & fees
18 Oct - 19 Oct
JW Marriott Panama
W Panama
Exterior
W Panama
5.0 star property
8.8 out of 10, Excellent, (1002)
"I liked the upscale look of the hotel and how clean it was throughout. The staff were nice and speak English. Any time I had questions or needed assistance they did not hesitate to provide it. I would highly recommend it."
The price is SAR 597
SAR 647 total
includes taxes & fees
13 Oct - 14 Oct
W Panama
Bristol Panama, a Registry Collection Hotel
Room
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1001)
"Gorgeous hotel in the heart of the city. Staff went above and beyond to cater to our every need. The pool is a great way to unwind. The area seems safe and there are restaurants and pattiseries within walking distance. Dinner at the hotel was a culinary experience. Be sure to purchase breakfast the next morning. It was delightful and so many options!! All around we felt very relaxed and comfortable!! "
The price is SAR 622
SAR 684 total
includes taxes & fees
26 Oct - 27 Oct
Bristol Panama, a Registry Collection Hotel
Hilton Panama
Room
Hilton Panama
5.0 star property
8.8 out of 10, Excellent, (1002)
"Muy buen sitio para hospedarse, estuve 3 noches por trabajo. Me apoyaron con la habitacion antes de la hora de check-in a un fee considerable, la habitacion muy amplia, bano y regadera OK, buen room service."
The price is SAR 588
SAR 647 total
includes taxes & fees
4 Oct - 5 Oct
Hilton Panama
The Westin Playa Bonita Panama
Exterior
The Westin Playa Bonita Panama
5.0 star property
8.0 out of 10, Very Good, (981)
"The staff awesome 😎"
The price is SAR 635
SAR 688 total
includes taxes & fees
2 Oct - 3 Oct
The Westin Playa Bonita Panama
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Pool
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
9.6 out of 10, Exceptional, (500)
"This was an amazing resort! Everyone was so nice and friendly. "
The price is SAR 730
SAR 794 total
includes taxes & fees
18 Oct - 19 Oct
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Veneto Hotel & Casino
Pool
Veneto Hotel & Casino
5.0 star property
6.2 out of 10, (997)
"Actually didn't stay, the hotel is closed and out of business"
Veneto Hotel & Casino
Megapolis Hotel Panamá
Outdoor pool
Megapolis Hotel Panamá
5.0 star property
8.4 out of 10, Very Good, (1000)
"This is THE place to stay in Panama City... it's location, friendly accommodating staff, and the amenities are fantastic. The rooms were wonderful, clean and bright. We tried Tauro (steakhouse) and the Bazaar - they were both delicious and the service excellent. We literally partied like rock stars at their rooftop restaurant, and at the wonderful outdoor infinity pool as well. We will definitely be returning! "
Megapolis Hotel Panamá
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Ana.
Decapolis Hotel Panama City

Decapolis Hotel Panama City

Avenida Balboa Con Multicentro, Panama City, Panama
The price is SAR88 per night from Oct 16 to Oct 17
SAR88
per night
Oct 16 - Oct 17
8.4/10 Very Good! (1,004 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in Santa Ana?
According to reviews by our customers, Villa Palma Boutique Hotel is one of the best properties for an indulgent stay in the Panama City neighborhood of Santa Ana. Want more 5-star hotels around the area? Waldorf Astoria Panama and Hilton Panama will cater to your upscale desires.
How much does it cost to stay in a 5-star hotel in Santa Ana?
The amount you pay for a 5-star hotel in Santa Ana can vary according to when you prefer to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to land the best deal on a high-end getaway.

  • Search for the lowest price per night from SAR88

What makes a hotel 5 stars in Santa Ana?
From high-end dining venues and 24-hour fitness centers to swimming pools and premium bedding, the 5-star experience in Santa Ana is all about luxury and comfort. But it requires more than just upscale conveniences to receive a 5-star rating. Hotels must also offer superior guest services like in-room massages, laundry and dry cleaning and room service any time day or night.
Are there any 5-star all-inclusive resorts in Santa Ana?
Expedia’s filter tool is the best way to search for exactly what you’re looking for. Select “5-star” and “All inclusive” to show the most luxurious hotels in Santa Ana where your meals, room, entertainment and activities are included in the upfront price. At these getaways, your trip is pure leisure from the moment you put down your suitcase.
What are the top 5-star spa hotels in Santa Ana?
If you’re looking for some TLC, you can’t beat W Panama. Other 5-star spa properties that are renowned for their rejuvenating treatments are Hilton Panama and Waldorf Astoria Panama, also found in or around Santa Ana.
Are there any 5-star vacation rentals in Santa Ana?
Although there aren’t any 5-star vacation rentals in Santa Ana on our site, we have a range of stays that promise a fantastic getaway. Discover one that matches your needs by searching our vacation rentals in Santa Ana.