Photo by Isa

Find 5 Star Hotels in Santa Ana from SAR 333

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Santa Ana 5 Star Hotels

Compare Santa Ana 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (3958)
"Beautiful and clean "
The price is SAR 446
SAR 491 total
includes taxes & fees
21 Apr - 22 Apr
Hotel Riu Plaza Panama

W Panama

5.0 star property
8.8 out of 10, Excellent, (1123)
"Amazinggg place ! Def would book again"
The price is SAR 717
SAR 789 total
includes taxes & fees
26 Apr - 27 Apr
W Panama

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1052)
"Ok"
The price is SAR 826
SAR 908 total
includes taxes & fees
13 Apr - 14 Apr
Waldorf Astoria Panama

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1144)
"Love the staff"
The price is SAR 1,122
SAR 1,234 total
includes taxes & fees
12 Apr - 13 Apr
JW Marriott Panama

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1103)
"Only place I stay "
The price is SAR 622
SAR 684 total
includes taxes & fees
26 Apr - 27 Apr
Bristol Panama, a Registry Collection Hotel

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (419)
"It’s a beautiful hotel and the service is exceptional. The pool area and the views are very special. I would also like to commend some of the staff who were most helpful and friendly during my stay. Julissa in room service was very friendly and genuinely committed to her guests, a smiling face to greet me each morning. Jesus at the front desk and Shaun both went above and beyond to help answer my questions and replace a lost key. The staff represent the hotel and the warm and friendly country of...
The price is SAR 1,097
SAR 1,207 total
includes taxes & fees
8 Apr - 9 Apr
Sofitel Legend Casco Viejo, Panama City

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1083)
"The hotel itself was lovely and the pools were great. I loved being on the ocean, but the beach itself was not very good. The resort was at least a 20 minute drive from the city, and the traffic over the Puente de las Americas was awful during rush hour The resort is also somewhat remote. I wanted to go out to dinner one night without going into Panama City and I found it very difficult to find a decent restaurant."
The price is SAR 797
SAR 876 total
includes taxes & fees
23 Apr - 24 Apr
The Westin Playa Bonita Panama

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1119)
"This was a very nice property and location. Next time I would stay in Casco Viejo because everything was there. This was a great location as well especially if you’re looking for a quieter area."
The price is SAR 798
SAR 878 total
includes taxes & fees
11 Apr - 12 Apr
Hilton Panama

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (554)
"Awesome everything "
The price is SAR 797
SAR 876 total
includes taxes & fees
18 Apr - 19 Apr
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Renaissance Panama City Hotel

5.0 star property
7.6 out of 10, Good, (795)
"I most appreciated the hospitality and professionalism."
The price is SAR 446
SAR 491 total
includes taxes & fees
11 Apr - 12 Apr
Renaissance Panama City Hotel

Veneto Hotel & Casino

5.0 star property
6.2 out of 10, (998)
"Actually didn't stay, the hotel is closed and out of business"
Veneto Hotel & Casino
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Ana.
Still don't see what you're looking for?
See all properties in Santa Ana.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Ana

Trip time! Discover the parks and museums in Santa Ana.

View from the fish market
go there and eat fresh and yummy fish in all variations
Photo by Isa
Open Photo by Isa

Frequently asked questions

What are the best 5-star hotels in Santa Ana?
According to reviews by our customers, Villa Palma Boutique Hotel is one of the best properties for an indulgent stay in the Panama City neighborhood of Santa Ana. Want more 5-star hotels around the area? Waldorf Astoria Panama and Hilton Panama will cater to your upscale desires.
How much does it cost to stay in a 5-star hotel in Santa Ana?
The amount you pay for a 5-star hotel in Santa Ana can vary according to when you prefer to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to land the best deal on a high-end getaway.

  • Search for the lowest price per night from SAR 333

What makes a hotel 5 stars in Santa Ana?
From high-end dining venues and 24-hour fitness centers to swimming pools and premium bedding, the 5-star experience in Santa Ana is all about luxury and comfort. But it requires more than just upscale conveniences to receive a 5-star rating. Hotels must also offer superior guest services like in-room massages, laundry and dry cleaning and room service any time day or night.
Are there any 5-star all-inclusive resorts in Santa Ana?
Expedia’s filter tool is the best way to search for exactly what you’re looking for. Select “5-star” and “All inclusive” to show the most luxurious hotels in Santa Ana where your meals, room, entertainment and activities are included in the upfront price. At these getaways, your trip is pure leisure from the moment you put down your suitcase.
What are the top 5-star spa hotels in Santa Ana?
If you’re looking for some TLC, you can’t beat W Panama. Other 5-star spa properties that are renowned for their rejuvenating treatments are Hilton Panama and Waldorf Astoria Panama, also found in or around Santa Ana.
Are there any 5-star vacation rentals in Santa Ana?
Although there aren’t any 5-star vacation rentals in Santa Ana on our site, we have a range of stays that promise a fantastic getaway. Discover one that matches your needs by searching our vacation rentals in Santa Ana.