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Find hotels in San Francisco, Panama City from SAR 172
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Discover 1,396 San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
9.2 out of 10, Wonderful, (2038)
The price is SAR 354
SAR 389 total
includes taxes & fees
3 Apr - 4 Apr

Ramada Plaza By Wyndham Panama Punta Pacífica
Ramada Plaza By Wyndham Panama Punta Pacífica
9.6 out of 10, Exceptional, (1095)
The price is SAR 375
SAR 413 total
includes taxes & fees
1 Apr - 2 Apr

Megapolis Hotel Panamá
Megapolis Hotel Panamá
8.4 out of 10, Very Good, (828)
The price is SAR 436
SAR 479 total
includes taxes & fees
30 Mar - 31 Mar

Decapolis Hotel Panama City
Decapolis Hotel Panama City
8.4 out of 10, Very Good, (1272)
The price is SAR 351
SAR 386 total
includes taxes & fees
30 Mar - 31 Mar

Aloft Panama
Aloft Panama
8.6 out of 10, Excellent, (791)
The price is SAR 427
SAR 470 total
includes taxes & fees
20 Apr - 21 Apr

Sheraton Grand Panama
Sheraton Grand Panama
8.6 out of 10, Excellent, (853)
The price is SAR 478
SAR 526 total
includes taxes & fees
18 Apr - 19 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Francisco
Where to stay in San Francisco
Hotels in top Panama City neighborhoods Learn more about San Francisco

Casco Viejo
4.5/5(178 area reviews)
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.
Recent reviews of San Francisco hotels
Recent reviews of San Francisco hotels

Hotel Riu Plaza Panama
5/5 Excellent
"Beautiful and clean "
A verified traveler stayed at Hotel Riu Plaza Panama
Posted 3 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in top Panama City neighborhoods
- Hotels in Casco Viejo
- Hotels in Bella Vista
- Hotels in El Cangrejo
- Hotels in San Francisco
- Hotels in San Felipe
- Hotels in Calidonia
- Hotels in Punta Paitilla
- Hotels in Costa del Este
- Hotels in Marbella
- Hotels in Punta Pacifica
- Hotels in Obarrio
- Hotels in Amador
- Hotels in Santa Ana
- Hotels in Balboa
- Hotels in Bethania
- Hotels in El Chorrillo
- Hotels in Juan Diaz
- Hotels in Parque Lefevre
- Hotels in Pueblo Nuevo
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Hotels near popular Panama City Attractions
- Hotels near Multiplaza Pacific Mall
- Hotels near Avenida Balboa
- Hotels near ATLAPA Conventions Center
- Hotels near Multicentro Panama
- Hotels near Pacific Center
- Hotels near Hospital Punta Pacífica
- Hotels near Panama Canal Murals
- Hotels near Omar Torrijos Recreational Park
- Hotels near Colonial Religious Art Museum
- Hotels near Albrook Shopping Mall
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