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Find hotels in San Francisco, Panama City from SAR 145
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Discover 1,405 San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Ramada Plaza By Wyndham Panama Punta Pacífica
Ramada Plaza By Wyndham Panama Punta Pacífica
9.6 out of 10, Exceptional, (997)
The price is SAR 422
SAR 464 total
includes taxes & fees
7 May - 8 May

Aloft Panama
Aloft Panama
8.6 out of 10, Excellent, (798)
The price is SAR 427
SAR 470 total
includes taxes & fees
18 May - 19 May

Megapolis Hotel Panamá
Megapolis Hotel Panamá
8.4 out of 10, Very Good, (864)
The price is SAR 477
SAR 524 total
includes taxes & fees
26 Apr - 27 Apr

San Francisco by Wynwood House
San Francisco by Wynwood House
9.6 out of 10, Exceptional, (36)
The price is SAR 333
SAR 460 total
includes taxes & fees
19 May - 20 May

Decapolis Hotel Panama City
Decapolis Hotel Panama City
8.6 out of 10, Excellent, (1160)
The price is SAR 351
SAR 386 total
includes taxes & fees
26 Apr - 27 Apr

Courtyard by Marriott Panama Multiplaza Mall
Courtyard by Marriott Panama Multiplaza Mall
8.8 out of 10, Excellent, (1000)
The price is SAR 443
SAR 488 total
includes taxes & fees
17 May - 18 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Francisco
Where to stay in San Francisco
Hotels in top Panama City neighborhoods Learn more about San Francisco

Casco Viejo
4.5/5(178 area reviews)
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.
Recent reviews of San Francisco hotels
Recent reviews of San Francisco hotels

Hotel Riu Plaza Panama
5/5 Excellent
"I loved everything about the hotel. They offer breakfast and two bottles of water for the room."
A verified traveler stayed at Hotel Riu Plaza Panama
Posted 16 hours ago
Explore a world of travel with Expedia
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Hotels in top Panama City neighborhoods
- Hotels in Casco Viejo
- Hotels in Bella Vista
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- Hotels in Punta Paitilla
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- Hotels in Punta Pacifica
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Hotels near popular Panama City Attractions
- Hotels near Multiplaza Pacific Mall
- Hotels near Avenida Balboa
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- Hotels near Pacific Center
- Hotels near Panama Canal Murals
- Hotels near Hospital Punta Pacífica
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- Hotels near Colonial Religious Art Museum
- Hotels near Albrook Shopping Mall
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