Find Resorts & Hotels with Spas in Sanibel, FL

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Check availability on Sanibel Resorts & Hotels with Spas

Compare Sanibel Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Sanibel Island Beach Resort

3.0 star property
9.0 out of 10, Wonderful, (1092)
"It’s a beautiful place to stay for a great weekend"
The price is SAR 953
SAR 1,157 total
includes taxes & fees
11 May - 12 May
Sanibel Island Beach Resort

Island Inn

3.5 star property
9.4 out of 10, Exceptional, (1074)
"Gulf front property with covered parking. Immaculately clean with beautiful decor. Lovely screened in porch with a sink/counter to wash your seashells or other use that you might have. Staff is friendly and knowledgeable about area dining options. We didn’t take advantage of all amenities but there are many. "
The price is SAR 1,609
SAR 1,794 total
includes taxes & fees
1 May - 2 May
Island Inn

Tarpon Tale Inn

3.0 star property
9.6 out of 10, Exceptional, (381)
"Owners on site and very engaged in making sure your stay is a good one"
The price is SAR 1,047
SAR 1,167 total
includes taxes & fees
24 Apr - 25 Apr
Tarpon Tale Inn

THE Palmview AND Sandpiper Inns

3.5 star property
9.4 out of 10, Exceptional, (163)
"Wonderful property and accommodation! Really enjoyed our stay. What a lovely place and so close to everything! "
THE Palmview AND Sandpiper Inns

Casa Ybel Resort

2.5 star property
8.8 out of 10, Excellent, (289)
"Both the staff and resort were wonderful. Very clean place. Staff at the hotel, restaurants and pool were all very sweet and helpful. Would highly recommend this resort for families as the units are spacious, have full kitchens, and an outdoor screened in porch. The only negative was that the beach chairs are not included in the stay. You would need to rent them daily or by the week or get your own beach chairs and umbrellas from a local shop and bring them to the beach. Even with that...
Casa Ybel Resort

Sanibel Home ready for rentals ! Now reduced for April and May 2025!

Sanibel Home ready for rentals ! Now reduced for April and May 2025!

Sundial Beach Resort & Spa

5.0 star property
8.6 out of 10, Excellent, (2563)
"It was very loud early mornings to late afternoon The people were friendly, we were in an area that was barely finished The beach was fantastic as always for the money we spent it was not worth it because of the area of the room ."
The price is SAR 1,567
SAR 2,241 total
includes taxes & fees
29 Apr - 30 Apr
Sundial Beach Resort & Spa

Stunning Luxury villa "Sandpiper" across the street from the beach!

9.2 out of 10, Wonderful, (36)
"Stayed for 14 nichts, very clean and quiet place. Close walk to the beach. We loved it. "
The price is SAR 859
SAR 2,037 total
includes taxes & fees
1 May - 2 May
Stunning Luxury villa "Sandpiper" across the street from the beach!

Macaw cottage, newly remodeled, walking distance to beach, shops, restaurants!

9.6 out of 10, Exceptional, (49)
"Great location! Loved access to beach chairs, towels and bikes. Cute rental that has everything you need. Beach is walking distance. Wickies restaurant across the street is amazing!"
The price is SAR 746
SAR 1,223 total
includes taxes & fees
1 May - 2 May
Macaw cottage, newly remodeled, walking distance to beach, shops, restaurants!

Pet friendly paradise on Sanibel Island with private beach - Unit 12

9.6 out of 10, Exceptional, (4)
"Small quiet condo with excellent beach access! Dog friendly complex!! Great experience and nice complex for families."
Pet friendly paradise on Sanibel Island with private beach - Unit 12
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Sanibel?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers love the beaches in Sanibel. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Sanibel?
Among Expedia’s 922 accommodation options in Sanibel, there are 2 spa hotels.
What's there to see and do in Sanibel?
Enjoy Sanibel and visit Sanibel Island Northern Beach, Sanibel Island Lighthouse, and Periwinkle Way. If you have extra time while you’re in the area, you might want to see Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge.
What is a Sanibel spa hotel?
Spa hotels in Sanibel provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.