Find Resorts & Hotels with Spas in Sanibel, FL

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Check availability on Sanibel Resorts & Hotels with Spas

Compare Sanibel Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Sanibel Island Beach Resort
Exterior

Sanibel Island Beach Resort

3.0 star property
8.8 out of 10, Excellent, (1313)
"Wonderful beachfront property with lovely pool and convenient pool bar and restaurant. Also appreciated the on site mini market and restaurant. Renovations are tastefully done post storms. Unavoidable in Florida but some dampness in rooms and the little no-seeum bugs outside were terrible in the evenings but the hotel had bug spray for sale and forewarned guests about that which was helpful! Really enjoyed our stay and would come back."
The price is SAR 985
SAR 1,192 total
includes taxes & fees
27 Apr - 28 Apr
Sanibel Island Beach Resort
Island Inn
Luxury Suite, Sea View | Beach/ocean view

Island Inn

3.5 star property
9.4 out of 10, Exceptional, (1071)
"Exactly as shown and described. "
The price is SAR 1,309
SAR 1,460 total
includes taxes & fees
20 Apr - 21 Apr
Island Inn
Tarpon Tale Inn
Exterior

Tarpon Tale Inn

3.0 star property
9.6 out of 10, Exceptional, (379)
"Such a great place with amazing staff and amenities. We have been here before and will definitely return."
The price is SAR 1,047
SAR 1,167 total
includes taxes & fees
29 Apr - 30 Apr
Tarpon Tale Inn
THE Palmview AND Sandpiper Inns
Exterior

THE Palmview AND Sandpiper Inns

3.5 star property
9.4 out of 10, Exceptional, (159)
"Wonderful property and accommodation! Really enjoyed our stay. What a lovely place and so close to everything! "
THE Palmview AND Sandpiper Inns
Casa Ybel Resort
Aerial view

Casa Ybel Resort

2.5 star property
8.8 out of 10, Excellent, (289)
"Both the staff and resort were wonderful. Very clean place. Staff at the hotel, restaurants and pool were all very sweet and helpful. Would highly recommend this resort for families as the units are spacious, have full kitchens, and an outdoor screened in porch. The only negative was that the beach chairs are not included in the stay. You would need to rent them daily or by the week or get your own beach chairs and umbrellas from a local shop and bring them to the beach. Even with that...
Casa Ybel Resort
Sanibel Home ready for rentals ! Now reduced for April and May 2025!
A heated pool

Sanibel Home ready for rentals ! Now reduced for April and May 2025!

Sanibel Home ready for rentals ! Now reduced for April and May 2025!
Shell Island Beach Club
Beach nearby, sun loungers, beach towels

Shell Island Beach Club

4.0 star property
9.4 out of 10, Exceptional, (6)
"They are still rebuilding from the storms so none of the outdoor amenities were open yet. We were informed of this when we booked.The condo was very clean & had everything we needed. I would definitely stay there again!"
Shell Island Beach Club
Sundial Beach Resort & Spa
Outdoor pool, cabanas (surcharge), pool umbrellas

Sundial Beach Resort & Spa

5.0 star property
8.6 out of 10, Excellent, (2560)
"Resort was very clean. Staff were very friendly. Received $180.00 food/ service credit on arrival because some of the resort areas are under renovation because of the Hurricane last fall. My room was so nice and the bed was luxurious. Beach was beautiful!!!"
The price is SAR 1,722
SAR 2,330 total
includes taxes & fees
27 Apr - 28 Apr
Sundial Beach Resort & Spa
Stunning Luxury villa "Sandpiper" across the street from the beach!
Beach nearby

Stunning Luxury villa "Sandpiper" across the street from the beach!

9.2 out of 10, Wonderful, (35)
"Let me start by saying that we've been to Sanibel many times - it's one of our favorite places. We've rented all over the island.Property is in a great location. It's near many restaurants, shops, markets, etc. (within a 5 min drive). Very short walk to the stunning beach. Property management company was outstanding to work with, and check-in/check-out was flawless. Unit offers everything you need.The only issue was the condition of the unit. The vertical blinds in the living room were broken...
The price is SAR 859
SAR 2,037 total
includes taxes & fees
1 May - 2 May
Stunning Luxury villa "Sandpiper" across the street from the beach!
Macaw cottage, newly remodeled, walking distance to beach, shops, restaurants!
Aerial view

Macaw cottage, newly remodeled, walking distance to beach, shops, restaurants!

9.6 out of 10, Exceptional, (48)
"Cute room that had everything we needed. Bikes and beach wagons were a nice addition. Close to lighthouse with good restaurant and ice cream shop across the street. The only negative was that the hot water ran out quickly during showers. Nice to see Sanibel rebounding from the hurricanes. "
The price is SAR 746
SAR 1,227 total
includes taxes & fees
1 May - 2 May
Macaw cottage, newly remodeled, walking distance to beach, shops, restaurants!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Sanibel?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers love the beaches in Sanibel. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Sanibel?
Among Expedia’s 922 accommodation options in Sanibel, there are 2 spa hotels.
What's there to see and do in Sanibel?
Enjoy Sanibel and visit Sanibel Island Northern Beach, Sanibel Island Lighthouse, and Periwinkle Way. If you have extra time while you’re in the area, you might want to see Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge.
What is a Sanibel spa hotel?
Spa hotels in Sanibel provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.