Find Resorts & Hotels with Spas in Sanibel, FL

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Check availability on Sanibel Resorts & Hotels with Spas

Compare Sanibel Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Sanibel Island Beach Resort

3.0 star property
8.8 out of 10, Excellent, (1029)
"This area has been through multiple hurricanes so to see how clean it is already just shows how passionate the area is to get it back on track to make it enjoyable. Beautiful beaches, incredible humble people. For a short relaxing getaway that we’re looking for, it was perfect. "
The price is SAR 1,081
SAR 1,299 total
includes taxes & fees
30 Jan - 31 Jan
Sanibel Island Beach Resort

Island Inn

3.5 star property
9.4 out of 10, Exceptional, (1067)
"Given the recent devastation caused by hurricanes to Sanibel Island, the Island Inn has bounced back remarkably. Good people and good accommodations. We definitely enjoyed our stay and plan on doing so again. "
The price is SAR 2,247
SAR 2,505 total
includes taxes & fees
4 Feb - 5 Feb
Island Inn

Tarpon Tale Inn

3.0 star property
9.6 out of 10, Exceptional, (378)
"This place was beautiful and very accommodating. It was a short walk or bike ride to the beach. The room had everything we needed and beach chairs, beach cart and bicycles were provided. It was right across from a coffee and ice cream shop and a nice restaurant and a gift shop. I will definitely be back to visit."
The price is SAR 1,722
SAR 1,920 total
includes taxes & fees
31 Jan - 1 Feb
Tarpon Tale Inn

THE Palmview AND Sandpiper Inns

3.5 star property
9.4 out of 10, Exceptional, (150)
"We absolutely loved it and would stay again. Only 2 things were the water pressure is nonexistent in the shower which after a day at the beach and trying to wash the sand off isn’t fun and I wish there was a potholder in the room. It’s fully stocked to cook and use the oven but we didn’t have anything to remove the stuff from the oven. But still absolutely would recommend. "
THE Palmview AND Sandpiper Inns

Casa Ybel Resort

2.5 star property
8.8 out of 10, Excellent, (289)
"Both the staff and resort were wonderful. Very clean place. Staff at the hotel, restaurants and pool were all very sweet and helpful. Would highly recommend this resort for families as the units are spacious, have full kitchens, and an outdoor screened in porch. The only negative was that the beach chairs are not included in the stay. You would need to rent them daily or by the week or get your own beach chairs and umbrellas from a local shop and bring them to the beach. Even with that...
Casa Ybel Resort

Sanibel Home ready for rentals !

Sanibel Home ready for rentals !

FULLY RESTORED! Rare Walkout Condo On Sanibel Beach

10.0 out of 10, Exceptional, (86)
"There really isn't much more to say. The unit and location were perfect for our wants and needs. Couldn't be happier with the entire process. Our host was very welcoming and responsive. Hope to come back again sometime."
FULLY RESTORED! Rare Walkout Condo On Sanibel Beach

SANIBEL SUN CASTLE - Splendid home, great location, heated pool, bike to beach

9.8 out of 10, Exceptional, (89)
"Rooms/kitchen were great! House worked great for 4 people Loved pool area."
SANIBEL SUN CASTLE - Splendid home, great location, heated pool, bike to beach

Stunning Luxury villa "Sandpiper" across the street from the beach!

9.2 out of 10, Wonderful, (33)
"Condo has been nicely updated. However only on space per condo for parking and they are not marked. We came home early New Years Eve and all spots were taken. Luckily we knew others on island and could park at their house and walk but was definitely an inconvenience. Their are 4 condors and room for 5 cars- all were taken "
The price is SAR 1,406
SAR 2,798 total
includes taxes & fees
31 Jan - 1 Feb
Stunning Luxury villa "Sandpiper" across the street from the beach!

Sanibel-Style on the East End! Walk to restaurants and the lighthouse. NEW!

9.6 out of 10, Exceptional, (38)
"Great place - thanks so much!"
The price is SAR 1,234
SAR 1,846 total
includes taxes & fees
2 Feb - 3 Feb
Sanibel-Style on the East End! Walk to restaurants and the lighthouse. NEW!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Sanibel?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers love the beaches in Sanibel. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Sanibel?
Among Expedia’s 922 accommodation options in Sanibel, there are 2 spa hotels.
What's there to see and do in Sanibel?
Enjoy Sanibel and visit Sanibel Island Northern Beach, Sanibel Island Lighthouse, and Periwinkle Way. If you have extra time while you’re in the area, you might want to see Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge.
What is a Sanibel spa hotel?
Spa hotels in Sanibel provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.