Find Resorts & Hotels with Spas in Panama City, FL

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Pick from 44 Panama City Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Hilton Garden Inn Panama City Airport
3.0 star property
9.4 out of 10, Exceptional, (441)
"Our experience was lovely!"
The price is SAR 407
SAR 431 total
includes taxes & fees
22 Nov - 23 Nov
Hilton Garden Inn Panama City Airport
Hotel Indigo Panama City Marina, an IHG Hotel
3.5 star property
9.6 out of 10, Exceptional, (180)
"Attention to details would put his place over the top with 5 stars. Entry way and elevator rugs were dirty and in need of vacuuming! Staff very pleasant and attentive. Unfortunately many homeless in the area and wandering the parking lot of the hotel all hours of the day and night! In need of security for theses reasons. Would stay again, room was very clean and the bed was so comfy! Definitely a good place to stay!"
The price is SAR 418
SAR 465 total
includes taxes & fees
24 Nov - 25 Nov
Hotel Indigo Panama City Marina, an IHG Hotel
La Quinta Inn & Suites by Wyndham Panama City
3.0 star property
8.6 out of 10, Excellent, (1001)
"The only issue I had was the noise. It sits right on U.S. Hwy 231. Traffic noise is excessive, especially if your room is on the highway side."
The price is SAR 282
SAR 316 total
includes taxes & fees
2 Dec - 3 Dec
La Quinta Inn & Suites by Wyndham Panama City
Red Roof Inn Panama City
2.0 star property
8.2 out of 10, Very Good, (1000)
"Room was clean, and big, front desk very helpful and polite. Bed very comfortable. Downside, breakfast was the usual Packaged stuff ( no hot food unless you count the waffle you make yourself) and the bathroom towels were very thin. Lucky there was two so I could dry myself. "
The price is SAR 330
SAR 374 total
includes taxes & fees
30 Nov - 1 Dec
Red Roof Inn Panama City
Courtyard by Marriott Panama City
3.0 star property
9.0 out of 10, Wonderful, (304)
"Clean"
The price is SAR 327
SAR 364 total
includes taxes & fees
2 Dec - 3 Dec
Courtyard by Marriott Panama City
Hilton Garden Inn Panama City
3.0 star property
8.6 out of 10, Excellent, (454)
"It was easy to get to and there were plenty of dining choices in the area."
The price is SAR 312
SAR 348 total
includes taxes & fees
29 Nov - 30 Nov
Hilton Garden Inn Panama City
Extended Stay America Select Suites - Panama City - Callaway
2.5 star property
6.2 out of 10, (431)
"All the amenities (Freezer, Fridge, Stove) - don't expect maid service but it was clean."
The price is SAR 221
SAR 234 total
includes taxes & fees
28 Nov - 29 Nov
Extended Stay America Select Suites - Panama City - Callaway
Quality Inn & Conference Center
2.5 star property
7.6 out of 10, Good, (505)
"Breakfast was great"
The price is SAR 228
SAR 254 total
includes taxes & fees
5 Dec - 6 Dec
Quality Inn & Conference Center
Rodeway Inn Panama City
2.0 star property
7.2 out of 10, Good, (317)
"It was cheap and the room was good "
The price is SAR 215
SAR 239 total
includes taxes & fees
5 Dec - 6 Dec
Rodeway Inn Panama City
TownePlace Suites by Marriott Panama City
2.5 star property
8.2 out of 10, Very Good, (148)
"H"
The price is SAR 320
SAR 354 total
includes taxes & fees
24 Nov - 25 Nov
TownePlace Suites by Marriott Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Panama City?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers love the array of shops in Panama City. Discover the beaches and seafood restaurants during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
How many spa hotels will I find in Panama City?
Among Expedia’s 186 accommodation options in Panama City, there are 6 spa hotels.
What's there to see and do in Panama City?
Enjoy all that Panama City has to offer and visit Panama City Marina, Panama City Mall, and Port Panama City. If you have spare time during your trip, you might want to make a stop at St. Andrews State Park and Naval Support Activity Panama City.
What is a Panama City spa hotel?
Spa hotels in Panama City provide lodging and have an on-site spa which offers services including facials as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.