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Find hotels in Otay Mesa West, San Diego from SAR 281
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Discover 6,539 Otay Mesa West hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Sycuan Casino Resort
Sycuan Casino Resort
9.2 out of 10, Wonderful, (1160)
The price is SAR 398
SAR 482 total
includes taxes & fees
14 Apr - 15 Apr

Days Inn by Wyndham San Diego-East/El Cajon
Days Inn by Wyndham San Diego-East/El Cajon
7.6 out of 10, Good, (1003)
The price is SAR 316
SAR 348 total
includes taxes & fees
13 Apr - 14 Apr

Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San Diego
8.2 out of 10, Very Good, (1001)
The price is SAR 387
SAR 426 total
includes taxes & fees
20 Apr - 21 Apr

SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake
9.6 out of 10, Exceptional, (295)
The price is SAR 657
SAR 723 total
includes taxes & fees
13 Apr - 14 Apr

Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista
9.8 out of 10, Exceptional, (1108)
The price is SAR 598
SAR 659 total
includes taxes & fees
20 Apr - 21 Apr

Heritage Inn La Mesa
Heritage Inn La Mesa
6.4 out of 10, (1012)
The price is SAR 287
SAR 316 total
includes taxes & fees
14 Apr - 15 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Otay Mesa West
Where to stay in Otay Mesa West
Hotels in top San Diego neighborhoods Learn more about Otay Mesa West

Downtown San Diego
3 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Recent reviews of Otay Mesa West hotels
Recent reviews of Otay Mesa West hotels

San Diego Mission Bay Resort
5/5 Excellent
"All of the staff were very happy, friendly and helpful. Would stay again. "
A verified traveler stayed at San Diego Mission Bay Resort
Posted 9 hours ago
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Otay Mesa West Hotels by Star Rating
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