Photo by Leonardo De Leon

Find hotels in Otay Mesa West, San Diego from SAR 255

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Discover 6,570 Otay Mesa West hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1227)
"Great Experience "
The price is SAR 402
SAR 487 total
includes taxes & fees
1 Apr - 2 Apr
Sycuan Casino Resort

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.8 out of 10, Good, (1106)
"It was nice, I would stay there again "
The price is SAR 335
SAR 369 total
includes taxes & fees
13 Apr - 14 Apr
Days Inn by Wyndham San Diego-East/El Cajon

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very Good, (1075)
"Very convenient "
The price is SAR 402
SAR 442 total
includes taxes & fees
20 Apr - 21 Apr
Best Western Plus La Mesa San Diego

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (278)
"Great stay. "
The price is SAR 656
SAR 723 total
includes taxes & fees
25 Apr - 26 Apr
SpringHill Suites by Marriott Chula Vista Eastlake

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1169)
"Friendly, efficient staff, lovely property. My only problem this visit was the water pressure in the shower. It fluctuated quite a bit during showering, which can be annoying. Also, it would be great if every hotel had housekeeping staff check the bathroom sink to make sure the plug actually works."
The price is SAR 635
SAR 699 total
includes taxes & fees
27 Apr - 28 Apr
Ayres Hotel San Diego South - Chula Vista

Heritage Inn La Mesa

2.0 star property
6.4 out of 10, (1144)
"Everything was good only thing is the coffee machine didn't work & no microwave you definitely need 1 not bad tho oh "
The price is SAR 277
SAR 305 total
includes taxes & fees
30 Mar - 31 Mar
Heritage Inn La Mesa

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1133)
"Wouls definitely stay here again. I had a great nights sleep!"
The price is SAR 510
SAR 563 total
includes taxes & fees
30 Mar - 31 Mar
Lamplighter Inn & Suites at SDSU

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.6 out of 10, Good, (1434)
"Convenient "
The price is SAR 411
SAR 452 total
includes taxes & fees
21 Apr - 22 Apr
Best Western Chula Vista/Otay Valley Hotel

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1205)
"Check in process was quick and painless. Very professional and friendly staff "
The price is SAR 388
SAR 427 total
includes taxes & fees
30 Mar - 31 Mar
La Quinta Inn by Wyndham San Diego Chula Vista

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (941)
"Dfghgdhj"
The price is SAR 263
SAR 296 total
includes taxes & fees
1 Apr - 2 Apr
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Valli Hi Motel

2.5 star property
8.2 out of 10, Very Good, (1021)
"I like this place it is comfortable and clean."
The price is SAR 304
SAR 342 total
includes taxes & fees
8 Apr - 9 Apr
Valli Hi Motel

Chula Vista Inn

2.5 star property
6.4 out of 10, (1096)
"Convert "
The price is SAR 304
SAR 334 total
includes taxes & fees
30 Mar - 31 Mar
Chula Vista Inn

Quality Inn San Diego South - Chula Vista

2.5 star property
7.6 out of 10, Good, (892)
"It is quite"
The price is SAR 296
SAR 325 total
includes taxes & fees
30 Mar - 31 Mar
Quality Inn San Diego South - Chula Vista

Days Inn by Wyndham Chula Vista/San Diego

2.0 star property
6.2 out of 10, (889)
"Clean and friendly "
The price is SAR 297
SAR 327 total
includes taxes & fees
22 Apr - 23 Apr
Days Inn by Wyndham Chula Vista/San Diego

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1812)
"Staff very professional "
The price is SAR 255
SAR 281 total
includes taxes & fees
30 Mar - 31 Mar
Hotel Palmeras Chula Vista

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1191)
"The property is nice, clean and modern. Ghe rooms are unfortunately small without a refrigerator. All things considered it was fine"
The price is SAR 384
SAR 423 total
includes taxes & fees
10 Apr - 11 Apr
Hercor Hotel - Urban Boutique

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.2 out of 10, Good, (1173)
"Good place "
The price is SAR 287
SAR 316 total
includes taxes & fees
13 Apr - 14 Apr
Howard Johnson by Wyndham National City/San Diego South

SureStay Hotel by Best Western Chula Vista San Diego Bay

3.0 star property
7.6 out of 10, Good, (1425)
"Very good service "
The price is SAR 319
SAR 351 total
includes taxes & fees
30 Mar - 31 Mar
SureStay Hotel by Best Western Chula Vista San Diego Bay

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very Good, (895)
"I have always enjoyed this place "
The price is SAR 320
SAR 354 total
includes taxes & fees
20 Apr - 21 Apr
Berkshire Motor Hotel

The Rambler Motel

3.0 star property
9.0 out of 10, Wonderful, (1952)
"Always a good stay "
The price is SAR 368
SAR 426 total
includes taxes & fees
31 Mar - 1 Apr
The Rambler Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Otay Mesa West
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What is Otay Mesa West like?

Otay Mesa West is a neighborhood that travelers like for its cathedral.

How many hotels can I expect to find in the Otay Mesa West area?

When you want to find places to stay in San Diego, start by booking one of Expedia's 5 hotels and other accommodations in Otay Mesa West.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the top deals on offer in Otay Mesa West.

Where can I learn more about changing or cancelling my trip to Otay Mesa West?

To find more details about rescheduling or cancelling your trip to Otay Mesa West, click here.

What is there to do around this San Diego neighborhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets, and Sesame Place San Diego. While you're out sightseeing in San Diego, be sure to visit other sights like Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.