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Find hotels in Otay Mesa West, San Diego from SAR 255
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Discover 6,522 Otay Mesa West hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Sycuan Casino Resort
Sycuan Casino Resort
9.2 out of 10, Wonderful, (1115)
The price is SAR 323
SAR 400 total
includes taxes & fees
5 Mar - 6 Mar

Days Inn by Wyndham San Diego-East/El Cajon
Days Inn by Wyndham San Diego-East/El Cajon
7.8 out of 10, Good, (1006)
The price is SAR 335
SAR 369 total
includes taxes & fees
9 Mar - 10 Mar
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Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San Diego
8.2 out of 10, Very Good, (1005)
The price is SAR 443
SAR 487 total
includes taxes & fees
9 Mar - 10 Mar

SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake
9.6 out of 10, Exceptional, (252)
The price is SAR 623
SAR 686 total
includes taxes & fees
4 Apr - 5 Apr

Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista
9.8 out of 10, Exceptional, (1139)
The price is SAR 571
SAR 629 total
includes taxes & fees
30 Mar - 31 Mar

Heritage Inn La Mesa
Heritage Inn La Mesa
6.2 out of 10, (1016)
The price is SAR 257
SAR 284 total
includes taxes & fees
6 Mar - 7 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Otay Mesa West
Where to stay in Otay Mesa West
Hotels in top San Diego neighborhoods Learn more about Otay Mesa West
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Downtown San Diego
3 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Recent reviews of Otay Mesa West hotels
Recent reviews of Otay Mesa West hotels
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Humphreys Half Moon Inn
5/5 Excellent
"Beautiful location and very friendly staff"
A verified traveler from San Diego stayed at Humphreys Half Moon Inn
Posted 12 hours ago
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Otay Mesa West Hotels by Star Rating
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