Otay Mesa West, CA

San Diego

Photo by Leonardo De Leon
Photo by Leonardo De Leon
Photo by Leonardo De Leon
Photo by Leonardo De Leon

Popular places to visit

Bayside Skyride at Sea World, San Diego, CA

SeaWorld

4.5/5(2,421 reviews)

Make time to visit the sea life at SeaWorld and find out why this is a popular attraction in San Diego. Discover the beautiful sunsets and top-notch restaurants in this walkable area.

SeaWorld
San Diego Zoo featuring landscape views, zoo animals and a pond

San Diego Zoo

4.5/5(3,565 reviews)

Why not visit the animals who live at San Diego Zoo and see why this is a favorite attraction in San Diego? Stroll along the area's seaside or experience its acclaimed art scene.

San Diego Zoo
Mission Bay featuring a sandy beach

Mission Bay

4.5/5(2,386 reviews)

Explore the great outdoors at Mission Bay, a popular spot to commune with nature in San Diego. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.

Mission Bay
San Diego Convention Center

San Diego Convention Center

4.5/5(1,297 reviews)

During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and entertainment choices.

San Diego Convention Center
Balboa Park which includes a pond

Balboa Park

4.5/5(3,715 reviews)

Explore the great outdoors with a trip to Balboa Park, a popular green space in San Diego. Discover the area's top-notch restaurants and its acclaimed theater scene.

Balboa Park
Mission Beach featuring tropical scenes, street scenes and a beach

Mission Beach

4.5/5(4,949 reviews)

Nothing says vacation like spending a lazy day at Mission Beach, a popular beach in San Diego. Stroll along the seaside or discover the area's sunsets.

Mission Beach

Otay Mesa West Hotel Deals

The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is SAR 634 per night from Mar 5 to Mar 6
SAR 634
SAR 714 total
includes taxes & fees
5 Mar - 6 Mar
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 spa tubs. Our guests praise the pool and the restaurant in ...
8.6/10 Excellent! (3,219 reviews)
"Front Staff was extremely nice"

Reviewed on 1 March 2025

The Dana on Mission Bay
Handlery Hotel
Handlery Hotel
3.5 out of 5
950 Hotel Cir N, San Diego, CA
The price is SAR 347 per night from Mar 6 to Mar 7
SAR 347
SAR 392 total
includes taxes & fees
6 Mar - 7 Mar
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
7.8/10 Good! (1,620 reviews)
"Very comfortable, safe and clean. Has a resort feel. Did not like expensive daily parking fee."

Reviewed on 3 March 2025

Handlery Hotel
Comfort Inn Sea World Area
Comfort Inn Sea World Area
3.5 out of 5
3880 Greenwood St, San Diego, CA
The price is SAR 371 per night from Mar 6 to Mar 7
SAR 371
SAR 418 total
includes taxes & fees
6 Mar - 7 Mar
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,688 reviews)
"Overall good"

Reviewed on 2 March 2025

Comfort Inn Sea World Area
Hyatt Regency Mission Bay Spa and Marina
Hyatt Regency Mission Bay Spa and Marina
4 out of 5
1441 Quivira Rd, San Diego, CA
The price is SAR 634 per night from Mar 9 to Mar 10
SAR 634
SAR 879 total
includes taxes & fees
9 Mar - 10 Mar
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,449 reviews)
"Hotel was nice. Quiet location on the marina. Kids liked the pool."

Reviewed on 1 March 2025

Hyatt Regency Mission Bay Spa and Marina
Omni San Diego Hotel
Omni San Diego Hotel
4 out of 5
675 L St, San Diego, CA
The price is SAR 777 per night from Apr 3 to Apr 4
SAR 777
SAR 1,041 total
includes taxes & fees
3 Apr - 4 Apr
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9/10 Wonderful! (1,866 reviews)
"We really enjoyed this property"

Reviewed on 1 March 2025

Omni San Diego Hotel
Hard Rock Hotel San Diego
Hard Rock Hotel San Diego
4 out of 5
207 5th Ave, San Diego, CA
The price is SAR 784 per night from Mar 7 to Mar 8
SAR 784
SAR 1,053 total
includes taxes & fees
7 Mar - 8 Mar
Stay at this 4-star hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our ...
8.8/10 Excellent! (2,594 reviews)
"Very clean, walking distance to downtown"

Reviewed on 2 March 2025

Hard Rock Hotel San Diego
See all 6,522 properties in Otay Mesa West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Otay Mesa West

Gaslamp Quarter showing signage, night scenes and street scenes

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Gaslamp Quarter
US Grant Hotel

Downtown San Diego

4.5/5(8,497 area reviews)

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Downtown San Diego
Little Italy

Little Italy

Little Italy is popular for its captivating waterfront views. Explore top sights like Waterfront Park and Maritime Museum of San Diego, and you can get around town on the metro at County Center - Little Italy Station.

Little Italy
Try the tamale eggs Benedict!

North Park

4/5(78 area reviews)

North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and Balboa Park.

North Park
Lake Murray in San Diego

Mid-City

If you're spending time in Mid-City, check out sights like Cal Coast Credit Union Open Air Theater or Viejas Arena and hop on the metro to see more the city at SDSU Transit Center Station or Alvarado Station.

Mid-City
Loads of Loafs

Hillcrest

3.5/5(53 area reviews)

Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Hillcrest

Otay Mesa West, CA

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