Find all hotels by Best Western in Florence, SC
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Tonight
Tomorrow
This weekend
Next weekend
Compare rooms and suites by Best Western in Florence with rates, reviews, and availability. Most hotels are fully refundable.

Best Western Inn
Best Western Inn
7.4 out of 10, Good, (969)
The price is SAR 371
SAR 416 total
includes taxes & fees
28 Mar - 29 Mar

Best Western Executive Inn
Best Western Executive Inn
8.2 out of 10, Very Good, (820)
The price is SAR 360
SAR 393 total
includes taxes & fees
13 Apr - 14 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Recent reviews of Florence hotels
Recent reviews of Florence hotels

Comfort Inn & Suites
5/5 Excellent
"Love the hotel"
A verified traveler stayed at Comfort Inn & Suites
Posted 1 day ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Florence Hotels by Brand
Hotels near popular Florence Attractions
- Hotels near Florence Civic Center
- Hotels near Magnolia Mall
- Hotels near Mcleod Regional Medical Center
- Hotels near Francis Marion University
- Hotels near Eastern Carolina Agricultural Fairgrounds
- Hotels near Florence Museum
- Hotels near Florence National Cemetery
- Hotels near Oakdale Country Club
- Hotels near Florence Veterans Park
- Hotels near Columns Plantation
More Hotel Options in Florence
- Adventure Hotels in Florence
- Beach Hotels in Florence
- Boutique Hotels in Florence
- Business Hotels in Florence
- Cheap Hotels in Florence
- Family Hotels in Florence
- Golf Hotels in Florence
- Historic Hotels in Florence
- Hotel Wedding Venues in Florence
- Hotel with a Concierge in Florence
- Hotels with Bars in Florence
- Hotels with Free Parking in Florence
- Hotels with Hot Tubs in Florence
- Hotels with WiFi in Florence
- Hotels with a Pool in Florence
- Hotels with an Indoor Pool in Florence
- Hotels with smoking rooms in Florence
- Luxury Hotels in Florence
- Pet-friendly Hotels in Florence
- Resorts & Hotels with Spas in Florence
- Romantic Hotels in Florence
- Shopping Hotels in Florence
More Accommodation Types in Florence
Explore more hotels
- Best Western Inn
- Home2 Suites by Hilton Florence, SC
- Days Inn by Wyndham Florence Near Civic Center
- Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
- La Quinta Inn & Suites by Wyndham Florence
- Aloft Florence
- Tru by Hilton Florence I-95
- SpringHill Suites by Marriott Florence
- Hilton Garden Inn Florence
- Courtyard by Marriott Florence
- Red Roof Inn Florence - Civic Center
- Hampton Inn & Suites Florence-North-I-95
- Country Inn & Suites by Radisson, Florence, SC
- TownePlace Suites by Marriott Florence
- Comfort Suites Florence I-95
- Sleep Inn Florence North
- Super 8 by Wyndham Florence
- Motel 6 Florence, SC
- Hotel Florence, Tapestry Collection by Hilton
- Econo Lodge