Find Boutique Hotels in Florence, SC

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Florence Boutique Hotels

Compare Florence Boutique Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Florence, Tapestry Collection by Hilton

3.0 star property
8.8 out of 10, Excellent, (548)
"Check in person not pleasant. Did not smile or was welcoming in any way or offer any suggestions for dining. Did not show us where elevator was located when there’s no sign. Disinterested attitude. "
The price is SAR 494
SAR 553 total
includes taxes & fees
9 Feb - 10 Feb
Hotel Florence, Tapestry Collection by Hilton

The Inn at the Crossroads

2.0 star property
9.4 out of 10, Exceptional, (656)
"Nice renovation. Nice location. Great experience. I recommend…"
The price is SAR 651
SAR 729 total
includes taxes & fees
27 Jan - 28 Jan
The Inn at the Crossroads

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (216)
"Great hotel! I always stay here for my trips to Hartsville!!!"
The price is SAR 638
SAR 715 total
includes taxes & fees
9 Feb - 10 Feb
The Mantissa Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Florence

Frequently asked questions

What's there to see and do in Florence?
The shopping and restaurants are just some of the things to enjoy while you’re in the area. Florence Museum, Florence National Cemetery, and Magnolia Mall are some of the local sights worth visiting. While you’re here, you might also like to explore more of the area and take in additional sights like Florence Veterans Park, Florence Civic Center, and Palmetto Shores Lake.
What kind of weather should I plan for when I travel to Florence?
Having a good idea of the weather in Florence will help you enjoy your stay to the fullest. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.
What's the best way to get to my boutique hotel in Florence?
You have a few options for getting to Florence. The nearest major airport is Florence, SC (FLO-Florence Regional), which is located 2.3 mi (3.7 km) from the heart of the city. If you want to explore the larger area, hop on a train at Florence Station.