Find hotels in East Prairie, MO from SAR 204

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Check East Prairie hotel prices

Tonight
5 Dhuʻl-Q. - 6 Dhuʻl-Q.
Tomorrow night
6 Dhuʻl-Q. - 7 Dhuʻl-Q.
This weekend
8 Dhuʻl-Q. - 10 Dhuʻl-Q.
Next weekend
15 Dhuʻl-Q. - 17 Dhuʻl-Q.

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Compare 76 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Super 8 by Wyndham Charleston/Sikeston East MO
Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
6.6 out of 10, (531)
"I just want to tell you I stay here a lot. I had never read the reviews before and it didn’t sound like a place I wanted to stay. But the rooms are big. On one side, you can come in from the outside or inside. It is close to halfway for me. Easy to get to. "
The price is SAR 233
SAR 259 total
includes taxes & fees
14 Nov - 15 Nov
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Cairo I-57
Exterior
Quality Inn Cairo I-57
2.5 star property
6.6 out of 10, (236)
"The room was very clean and the breakfast was pretty good. No complaints"
The price is SAR 217
SAR 239 total
includes taxes & fees
6 Dec - 7 Dec
Quality Inn Cairo I-57
Quality Inn Charleston - Sikeston
Exterior
Quality Inn Charleston - Sikeston
2.5 star property
6.8 out of 10, (357)
"Great bed. "
The price is SAR 224
SAR 242 total
includes taxes & fees
6 Dec - 7 Dec
Quality Inn Charleston - Sikeston
Eagle Inn Charleston
Exterior
Eagle Inn Charleston
2.0 star property
6.8 out of 10, (95)
"Comfortable bed, easy access to room"
The price is SAR 260
SAR 289 total
includes taxes & fees
14 Nov - 15 Nov
Eagle Inn Charleston
Charming 3-bedroom house near ball park in quiet neighborhood
Exterior detail
Charming 3-bedroom house near ball park in quiet neighborhood
The price is SAR 338
SAR 603 total
includes taxes & fees
7 Nov - 8 Nov
Charming 3-bedroom house near ball park in quiet neighborhood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in East Prairie?

Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Pear Tree Inn Sikeston and Days Inn and Suites by Wyndham Sikeston. See all available top hotels, or vacation rentals in East Prairie.

What are some of the best vacation rentals that East Prairie has to offer?

For Larger Groups (Up To 24) Right on Reelfoot Lake--Private Dock And Pier: Visitors like this East Prairie vacation home rental. It is located on a lake and has a balcony, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in East Prairie.

If I need to cancel my hotel reservation in East Prairie, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.

Where can I learn more about changing or cancelling my trip to East Prairie?

To access more information about rescheduling or cancelling your trip to East Prairie, click here.

What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?

Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.

What's it like to stay in East Prairie?

Visitors are sure to enjoy all that East Prairie has to offer. There are 29 hotels and other accommodations in the surrounding area. Find out more about East Prairie.

What should I do while I'm visiting East Prairie?

The picturesque setting of Mississippi River and Big Oak Tree State Park exemplify the area's natural beauty. You'll also find The Book Bug and New Madrid Historical Museum in the area. Check out what more to see and do in Expedia's East Prairie guide.

What's the weather like in East Prairie?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.