Find Resorts & Hotels with Spas in Big Pine Key, FL

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Check availability on Big Pine Key Resorts & Hotels with Spas

Compare Big Pine Key Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Old Wooden Bridge Resort and Marina

2.5 star property
8.6 out of 10, Excellent, (204)
"ENJOYED OUR STAY. BEDDING NEEDS ALOT OF IMPROVEMENT. ONE BEDROOM HAD AN OLD MATTRESS AND THE OTHER BED ONLY HAD A PAD OVER WOOD ! OUR HOUSEBOAT WAS OLDER AND NEEDED FLOOR REPAIRS. NICE PEOPLE, JIMMY HELPED WITH THE MARINA."
The price is SAR 559
SAR 1,004 total
includes taxes & fees
31 Mar - 1 Apr
Old Wooden Bridge Resort and Marina

Deer Run Bed & Breakfast

2.5 star property
8.0 out of 10, Very Good, (1)
"Loved it. Beautiful property."
Deer Run Bed & Breakfast

Tropical Caribbean Paradise with pool!

9.2 out of 10, Wonderful, (83)
"RV was very clean and comfortable. Perfect spot to end each day. The RV park was very quiet at night. Location was excellent close to both northern and southern keys. Would definitely recommend. "
Tropical Caribbean Paradise with pool!

🐠 HEATED SWIM SPA / OPEN WATER VIEWS / BOAT DOCK / LUXURIOUS / BUILT IN 2023🐬

10.0 out of 10, Exceptional, (4)
"This house and location was beautiful. Large enough to entertain friends.The kitchen and bathrooms were very well stocked with high end provisions. The views were great! We watched the sunrise from the living room and went up on top to watch the sunsets. We saw dolphins in the bay from the top and played cornhole with friends. We loved the swim spa...perfect combination of hot tub and pool. Martina was the best part of it, she was the perfect host! Very accommodating and prompt to solve any...
🐠 HEATED SWIM SPA / OPEN WATER VIEWS / BOAT DOCK / LUXURIOUS / BUILT IN 2023🐬

The most setup home in BPK TIKI HUT,POOL ,GRILL ,CANAL FRONT, FREE UNLIMITED ICE

9.2 out of 10, Wonderful, (5)
"Love,loved the pool.. neighbors were great!"
The most setup home in BPK TIKI HUT,POOL ,GRILL ,CANAL FRONT, FREE UNLIMITED ICE

Newly Remodeled Corner House on the Water

10.0 out of 10, Exceptional, (2)
"We enjoyed Jan/Feb at this property. The location is great & the house met all our needs. Property manager was very easy to work with. Caught lots of fish & enjoyed laidback BPK. "
Newly Remodeled Corner House on the Water

Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool

10.0 out of 10, Exceptional, (2)
"This property is making it to the top of our favorites! The view is the best. Very distracting when needing to work. The property was clean, everything worked, had everything we needed, the neighborhood was nice and quiet. Took full advantage of the kayaks and loved all the sea life we encountered. Lots of young sharks, sawfish, turtles, rays, sea slugs, crabs etc up in the shallows . Snorkeling right in front of the house, even tried our hand at lobster tickling. We brought jet skis and...
Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool

Banana Republics - Located in Paradise

10.0 out of 10, Exceptional, (1)
"We loved the property! The area was wonderful to walk the dog and see the key deer. The owner was very helpful with all our needs. We would absolutely stay there again!"
Banana Republics - Located in Paradise

Water Views / Heated Swimming Pool / Hot Tub / Boat Dock

10.0 out of 10, Exceptional, (1)
"This home is amazing. We really enjoyed the beautiful ocean view from the house and pool. We spent a lot of time in the heated pool and hot tub. There is a great downstairs and upstairs screened in area for relaxing. The kitchen was fully stocked and all beds were comfortable. This home has a large dock for a boat. It's easy boating access to both Bay and Ocean side. It's only 6 miles away from Lone Key, which is one of the greatest reefs in the world. It great for diving or snorkeling. We'll...
Water Views / Heated Swimming Pool / Hot Tub / Boat Dock

Big Pine Key Waterfront Home: Boating, Sunrises, Sunsets; Relax in Paradise!

10.0 out of 10, Exceptional, (32)
"We spent two incredible months at this house in Big Pine Key, and it was everything we could have hoped for! The location is unbeatable—right on the water, offering stunning views and easy access for boating, fishing, or just relaxing by the shore. The quiet neighborhood is full of local wildlife, including the friendly Key deer that often wandered by.The home itself is beautifully decorated in a stylish South Florida theme and was fully stocked with everything we needed—except for our food, of...
Big Pine Key Waterfront Home: Boating, Sunrises, Sunsets; Relax in Paradise!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Big Pine Key?
Treat yourself to some time in a luxurious spa hotel and you won’t regret it. Check out the beaches in Big Pine Key - worth a picture or two! Be sure to enjoy activities like kayaking and snorkeling during your stay. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Big Pine Key?
Among Expedia’s 88 accommodation options in Big Pine Key, there are 2 spa hotels.
What's there to see and do in Big Pine Key?
Enjoy all that Big Pine Key has to offer and visit Calusa Beach, Bahia Honda State Park, and Florida Keys Beaches. If you have extra time while you’re in the area, you might want to see Big Pine Key Flea Market and Cook Island.
What is a Big Pine Key spa hotel?
Spa hotels in Big Pine Key provide lodging and have an on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.