Find 5 Star Hotels in Big Pine Key, FL from SAR 813
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Big Pine Key 5 Star Hotels
Tonight
Tomorrow
This weekend
Next weekend
Compare Big Pine Key 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Isla Bella Beach Resort & Spa
Isla Bella Beach Resort & Spa
9.0 out of 10, Wonderful, (1007)
The price is SAR 1,572
SAR 2,015 total
includes taxes & fees
6 Apr - 7 Apr
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Big Pine Key.

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
1996 Overseas Highway, Marathon, FL
The price is SAR 813 per night from Apr 20 to Apr 21
SAR 813
SAR 1,062 total
includes taxes & fees
20 Apr - 21 Apr
8.8/10 Excellent! (1,344 reviews)
Still don't see what you're looking for?
See all properties in Big Pine Key.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Big Pine Key
Meet the local wildlife, splash in the shallows and enjoy the calm of the quieter Keys on this stretch of serene waterfront and wetlands.

Recent reviews of Big Pine Key hotels
Recent reviews of Big Pine Key hotels

Isla Bella Beach Resort & Spa
5/5 Excellent
"Amazing resort. Highly recommend. "
A verified traveler stayed at Isla Bella Beach Resort & Spa
Posted 2 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Big Pine Key Hotels by Star Rating
Stay near popular Big Pine Key attractions
- Hotels near Key West Visitors Center
- Hotels near National Key Deer Refuge Visitor Center
- Hotels near Big Pine Key Flea Market
- Hotels near Blue Hole
- Hotels near Coupon Bight Aquatic Preserve
- Hotels near Veterans Memorial Park & Beach
- Hotels near Sombrero Beach
- Hotels near Seven Mile Bridge
- Hotels near Curry Hammock State Park
- Hotels near Sunset Park Beach
More Hotel Options in Big Pine Key
- Adventure Hotels in Big Pine Key
- Beach Hotels in Big Pine Key
- Cheap Hotels in Big Pine Key
- Family Hotels in Big Pine Key
- Hotel Wedding Venues in Big Pine Key
- Hotel with a Concierge in Big Pine Key
- Hotels with Free Parking in Big Pine Key
- Hotels with Hot Tubs in Big Pine Key
- Hotels with WiFi in Big Pine Key
- Hotels with a Pool in Big Pine Key
- Pet-friendly Hotels in Big Pine Key
- Resorts & Hotels with Spas in Big Pine Key
- Romantic Hotels in Big Pine Key
- Shopping Hotels in Big Pine Key
- Ski Hotels in Big Pine Key
More Accommodation Types in Big Pine Key
- Vacation Homes in Big Pine Key
- Condo Rentals in Big Pine Key
- Apartments in Big Pine Key
- Cottages in Big Pine Key
- Villas in Big Pine Key
- RV Parks in Big Pine Key
- Resorts in Big Pine Key
- Houseboats in Big Pine Key
- Motels in Big Pine Key
- Cabin Rentals in Big Pine Key
- Aparthotels in Big Pine Key
- B&B in Big Pine Key
- Lodges in Big Pine Key
Explore more hotels
- Fairfield Inn & Suites by Marriott Marathon Florida Keys
- Courtyard by Marriott Faro Blanco Resort
- Tranquility Bay Beachfront Hotel and Resort
- Kingsail Resort
- Looe Key Reef Resort
- Rainbow Bend Resort
- Sugarloaf Key Hotel at KOA Resort
- Skipjack Resort & Marina
- Parmer's Resort
- Captain Pips Marina & Hideaway
- Hampton Inn Marathon - Florida Keys
- Sugar Loaf Lodge
- Floating Sea Cove Resort & Marina
- Glunz Ocean Beach Hotel & Resort
- Yacht Haven Marina
- Tropical Cottages
- Bonefish Bay Motel
- Delightful Aqualodge! Cabana Club Access!
- Gulf View Waterfront Resort
- Grassy Flats Resort & Beach Club