Find 5 Star Hotels in Florida Keys from SAR 1,161

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Florida Keys 5 Star Hotels

Compare Florida Keys 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Cheeca Lodge & Spa
Private beach, sun loungers, beach umbrellas, beach towels

Cheeca Lodge & Spa

5.0 star property
9.0 out of 10, Wonderful, (1049)
"The best of the best. "
The price is SAR 1,317
SAR 1,735 total
includes taxes & fees
6 Apr - 7 Apr
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa
Property grounds

Isla Bella Beach Resort & Spa

5.0 star property
9.0 out of 10, Wonderful, (1008)
"Amazing resort. Highly recommend. "
The price is SAR 1,497
SAR 1,928 total
includes taxes & fees
23 Mar - 24 Mar
Isla Bella Beach Resort & Spa
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Florida Keys.
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

97000 Overseas Hwy, Key Largo, FL
The price is SAR 1,370 per night from Apr 1 to Apr 2
SAR 1,370
SAR 1,748 total
includes taxes & fees
1 Apr - 2 Apr
8.6/10 Excellent! (1,000 reviews)
Still don't see what you're looking for?
See all properties in Florida Keys.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Swim with dolphins, snorkel over coral reefs, visit Ernest Hemingway’s home or just relax on a beach and enjoy the balmy climate of this beautiful group of islands.

See all hotels in Florida Keys
Higgs Beach showing a sandy beach and tropical scenes as well as a large group of people

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Florida Keys?
The amount you pay for a 5-star hotel in Florida Keys can vary depending on the time of year you travel and how long you plan to be away, among other factors. Use our price per night filter and other search tools to score the best deal on a luxurious stay.

  • Search for the lowest price per night from SAR 1,161

What makes a hotel 5 stars in Florida Keys?
In Florida Keys, a hotel needs to provide a specific level of upscale amenities to earn a 5-star rating. These may include gourmet restaurants, saunas and spas, on-site gyms, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding service. You’ll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer special touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Florida Keys?
Expedia’s filters are the best way to narrow down what you’re looking for. Select “5-star” and “All inclusive” to see the most luxurious properties in Florida Keys where your meals, room, activities and entertainment are included in the price. At these stays, your vacation is absolute indulgence from the moment you put down your suitcase.
Are there any 5-star vacation rentals in Florida Keys?
There are no 5-star vacation rentals in Florida Keys on our site, but there are a range of other top-rated properties worth checking out. Search through our vacation rentals in Florida Keys to book the best place for your stay.