Find hotels in Upstate South Carolina, SC from SAR 220
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Compare 2,599 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Comfort Suites Greenville Airport
Comfort Suites Greenville Airport
9.4 out of 10, Exceptional, (902)
The price is SAR 368
SAR 417 total
includes taxes & fees
6 Apr - 7 Apr

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference Center
8.8 out of 10, Excellent, (1005)
The price is SAR 484
SAR 548 total
includes taxes & fees
16 Mar - 17 Mar

Hampton Inn & Suites Greenville Airport, SC
Hampton Inn & Suites Greenville Airport, SC
9.2 out of 10, Wonderful, (861)
The price is SAR 399
SAR 452 total
includes taxes & fees
12 Apr - 13 Apr

Holiday Inn Express Hotel & Suites Greenville by IHG
Holiday Inn Express Hotel & Suites Greenville by IHG
9.0 out of 10, Wonderful, (896)
The price is SAR 431
SAR 484 total
includes taxes & fees
30 Mar - 31 Mar

The Abernathy of Clemson
The Abernathy of Clemson
9.6 out of 10, Exceptional, (495)
The price is SAR 709
SAR 787 total
includes taxes & fees
16 Mar - 17 Mar

Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & Suites
9.2 out of 10, Wonderful, (1329)
The price is SAR 317
SAR 349 total
includes taxes & fees
23 Mar - 24 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Upstate South Carolina, SC
Showing deals for:Mar 28 - Mar 30
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Hotel Hartness
Greenville
9.8/10Exceptional (472 reviews)
10% off
Price is SAR 1,290
per night
SAR 3,098 total
includes taxes & fees
Go beyond your typical stay in Upstate South Carolina
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Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism
Where to stay in Upstate South Carolina
Where to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina

Greenville Downtown
2 out of top 10 points of interest in this area
5/5(654 area reviews)
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
More cheap stays in Upstate South Carolina
More cheap stays in Upstate South Carolina

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd, Clemson, SC
The price is SAR 347 per night from Mar 26 to Mar 27
SAR 347
SAR 386 total
includes taxes & fees
26 Mar - 27 Mar
8.2/10 Very Good! (1,002 reviews)
Hotels in Upstate South Carolina with star-rating
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
14 properties
Stay near popular Upstate South Carolina attractions
Stay near popular Upstate South Carolina attractions

Clemson University
5/5(410 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
Recent reviews of Upstate South Carolina hotels
Recent reviews of Upstate South Carolina hotels

The Shepherd Hotel Downtown Clemson
5/5 Excellent
"Our favorite place while in Clemson, hands down!"
A verified traveler from new hope stayed at The Shepherd Hotel Downtown Clemson
Posted 1 day ago
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Stay near popular Upstate South Carolina attractions
- Hotels near Clemson University
- Hotels near BMW Performance Center
- Hotels near Haywood Mall
- Hotels near Falls Park on the Reedy
- Hotels near Lake Jocassee
- Hotels near Prisma Health Greenville Memorial Hospital
- Hotels near Greenville Convention Center
- Hotels near Bon Secours Wellness Arena
- Hotels near Bob Jones University
- Hotels near The Peace Center
- Hotels near Devils Fork State Park
- Hotels near Wofford College
- Hotels near Memorial Stadium
- Hotels near Anderson University
- Hotels near Fred W. Symmes Chapel
- Hotels near WestGate Mall
- Hotels near Fluor Field at the West End
- Hotels near Table Rock State Park
- Hotels near Frankie's Fun Park
- Hotels near University of South Carolina Upstate
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Explore more hotels
- Inn @ Clemson
- Lakeside Lodge Clemson
- Embassy Suites Greenville Golf Resort & Conference Center
- Holiday Inn Express Hotel & Suites Greenville by IHG
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- Mint House Greenville - Downtown
- Pet-friendly Central Cottage: 2 Miles to Clemson!
- Hotel Hartness
- The Westin Poinsett Greenville
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