Find 4 Star Hotels in Upstate South Carolina, SC from SAR 349
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Compare Upstate South Carolina 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
9.8 out of 10, Exceptional, (563)
The price is SAR 627
SAR 696 total
includes taxes & fees
11 May - 12 May

Grand Bohemian Lodge Greenville, Autograph Collection
Grand Bohemian Lodge Greenville, Autograph Collection
9.6 out of 10, Exceptional, (336)
The price is SAR 908
SAR 998 total
includes taxes & fees
25 May - 26 May

The Westin Poinsett Greenville
The Westin Poinsett Greenville
9.2 out of 10, Wonderful, (1000)
The price is SAR 671
SAR 761 total
includes taxes & fees
26 May - 27 May

Mint House Greenville - Downtown
Mint House Greenville - Downtown
9.4 out of 10, Exceptional, (655)
The price is SAR 503
SAR 568 total
includes taxes & fees
11 May - 12 May

Greenville Marriott
Greenville Marriott
8.6 out of 10, Excellent, (554)
The price is SAR 476
SAR 541 total
includes taxes & fees
11 May - 12 May

Hotel Hartness
Hotel Hartness
9.8 out of 10, Exceptional, (503)
The price is SAR 646
SAR 837 total
includes taxes & fees
18 May - 19 May

The Abernathy of Clemson
The Abernathy of Clemson
9.6 out of 10, Exceptional, (507)
The price is SAR 671
SAR 745 total
includes taxes & fees
14 May - 15 May

Mint House Greenville - West End
Mint House Greenville - West End
9.2 out of 10, Wonderful, (85)
The price is SAR 570
SAR 645 total
includes taxes & fees
26 May - 27 May
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Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism
Recent reviews of Upstate South Carolina hotels
Recent reviews of Upstate South Carolina hotels

The Shepherd Hotel Downtown Clemson
5/5 Excellent
"Excellent customer service at front desk. Staff is courteous and extend a warmth and welcome feeling."
A verified traveler stayed at The Shepherd Hotel Downtown Clemson
Posted 4 days ago
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Upstate South Carolina Hotels by Star Rating
Hotels in Upstate South Carolina Neighborhoods
Stay near popular Upstate South Carolina attractions
- Hotels near Clemson University
- Hotels near Falls Park on the Reedy
- Hotels near BMW Performance Center
- Hotels near Lake Jocassee
- Hotels near Haywood Mall
- Hotels near Prisma Health Greenville Memorial Hospital
- Hotels near Bon Secours Wellness Arena
- Hotels near Greenville Convention Center
- Hotels near The Peace Center
- Hotels near Wofford College
- Hotels near Fluor Field at the West End
- Hotels near Anderson University
- Hotels near Fred W. Symmes Chapel
- Hotels near Table Rock State Park
- Hotels near Memorial Stadium
- Hotels near Bob Jones University
- Hotels near Devils Fork State Park
- Hotels near University of South Carolina Upstate
- Hotels near Converse College
- Hotels near WestGate Mall
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Explore more hotels
- Lakeside Lodge Clemson
- La Quinta Inn & Suites by Wyndham Greenville Haywood
- Wooded Cottage - 3 Mi to Clemson University
- Hyatt Place Greenville/Haywood
- Homewood Suites by Hilton Greenville Downtown
- The Shepherd Hotel Downtown Clemson
- Holiday Inn Greenville - Woodruff Road by IHG
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- Comfort Inn Greenville - Haywood Mall
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