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Find hotels in Seneca, SC from SAR 217
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Compare 1,554 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Lakeside Lodge Clemson
Lakeside Lodge Clemson
9.0 out of 10, Wonderful, (836)
The price is SAR 409
SAR 505 total
includes taxes & fees
15 Apr - 16 Apr

Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
9.2 out of 10, Wonderful, (697)
The price is SAR 444
SAR 488 total
includes taxes & fees
20 Apr - 21 Apr

Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
9.4 out of 10, Exceptional, (588)
The price is SAR 455
SAR 501 total
includes taxes & fees
27 Apr - 28 Apr

Quality Inn Seneca US-123
Quality Inn Seneca US-123
8.0 out of 10, Very Good, (579)
The price is SAR 312
SAR 381 total
includes taxes & fees
5 May - 6 May

Best Western Seneca-Clemson
Best Western Seneca-Clemson
8.4 out of 10, Very Good, (580)
The price is SAR 335
SAR 369 total
includes taxes & fees
21 Apr - 22 Apr

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
9.4 out of 10, Exceptional, (139)
The price is SAR 484
SAR 533 total
includes taxes & fees
15 Apr - 16 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Seneca
Escape to Seneca! Enjoy its sports, lake views, and coffee.

Photo by Cindy Keese
Open Photo by Cindy Keese
Where to stay in Seneca
Where to stay in Seneca
Find the best Seneca areas and neighborhoods for the activities you enjoy most. Learn more about Seneca

Serenity Bay
Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Reservoir and Keowee Key Golf Course.
More cheap stays in Seneca
More cheap stays in Seneca

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd, Clemson, SC
The price is SAR 348 per night from Apr 20 to Apr 21
SAR 348
SAR 386 total
includes taxes & fees
20 Apr - 21 Apr
8.2/10 Very Good! (1,005 reviews)
Hotels in Seneca with star-rating
Hotels in Seneca with star-rating

4 Star Hotels
8 properties
Stay near popular Seneca attractions
Stay near popular Seneca attractions
Recent reviews of Seneca hotels
Recent reviews of Seneca hotels

Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
5/5 Excellent
Great weekend!
"I don’t think the beds were quite as advertised, but it worked out well for us, anyway. Great location! The driveway was quite steep and that was difficult for my elderly mother. We had two family members who couldn’t make the trip, and they would not have been able to park in the steep driveway. Otherwise, wonderful!!"
A verified traveler stayed at Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
Posted 2 days ago
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Explore more hotels
- Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub
- Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub
- NEW! Beautiful 5 bedroom Lake Keowee Cove Home!
- 6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
- Lakefront Cabin on Lake Keowee. Kayaks, paddle boards, modern & cozy!
- Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
- Fall fun at the cabin! Convenient to Lake Keowee and Clemson
- 😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks
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