Photo by Cindy Keese

Find hotels in Seneca, SC from SAR 217

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Compare 1,554 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Lakeside Lodge Clemson

2.5 star property
9.0 out of 10, Wonderful, (836)
"Great place"
The price is SAR 409
SAR 505 total
includes taxes & fees
15 Apr - 16 Apr
Lakeside Lodge Clemson

Tru by Hilton Seneca Clemson

2.5 star property
9.2 out of 10, Wonderful, (697)
"Have stayed here multiple times as daughter attends Clemson University. Had a problem with the a/c unit and unfortunately had to change rooms but Hannah, the front desk host, was absolutely wonderful in dealing with the situation. So friendly, compassionate and professional. She deserves a raise :)"
The price is SAR 444
SAR 488 total
includes taxes & fees
20 Apr - 21 Apr
Tru by Hilton Seneca Clemson

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (588)
"My room was very clean. Gave me the home vibe. Well visit again "
The price is SAR 455
SAR 501 total
includes taxes & fees
27 Apr - 28 Apr
Hampton Inn & Suites Seneca-Clemson Area

Quality Inn Seneca US-123

2.5 star property
8.0 out of 10, Very Good, (579)
"First room smelled of stale cigarette smoke, otherwise i would've rated them higher. Staff was EXTREMELY friendly and helpful. Front desk clerk moved us immediately to a different room. That room was very nice and comfortable. Would stay there again."
The price is SAR 312
SAR 381 total
includes taxes & fees
5 May - 6 May
Quality Inn Seneca US-123

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very Good, (580)
"Very clean rooms, and nice staff."
The price is SAR 335
SAR 369 total
includes taxes & fees
21 Apr - 22 Apr
Best Western Seneca-Clemson

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
9.4 out of 10, Exceptional, (139)
"Nice Room , friendly staff , nice and clean breakfast bar! "
The price is SAR 484
SAR 533 total
includes taxes & fees
15 Apr - 16 Apr
Fairfield Inn & Suites Seneca Clemson Univ Area

Postcard Cabins Lake Hartwell

2.0 star property
10.0 out of 10, Exceptional, (4)
"This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?"
The price is SAR 338
SAR 372 total
includes taxes & fees
27 Apr - 28 Apr
Postcard Cabins Lake Hartwell

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (671)
"Clean convenient to the grocery store fast food and backs up to a Lowe's very quiet "
The price is SAR 258
SAR 284 total
includes taxes & fees
20 Apr - 21 Apr
Days Inn by Wyndham Seneca / Clemson Area

Baymont by Wyndham Easley/Greenville

2.5 star property
7.2 out of 10, Good, (651)
"Room smelled of smoke. Agent gave us some spray to make the room smell better. No alternative room available "
The price is SAR 319
SAR 354 total
includes taxes & fees
15 Apr - 16 Apr
Baymont by Wyndham Easley/Greenville

Quality Inn & Suites Easley - Greenville

2.5 star property
7.0 out of 10, Good, (344)
"This location is a typical older style motel where the room connects to the outside sidewalk. If you’re trying to compare this location to a Marriott somewhere, then of course this location is going to fail. Putting this Quality Inn in the same box, however with other similar motels, I think it was perfectly fine. We had no complaints. Yes, some of the tile in the bathroom was aging, but we found the room clean, the beds were comfortable, the price was reasonable, and the breakfast was pretty...
The price is SAR 271
SAR 301 total
includes taxes & fees
20 Apr - 21 Apr
Quality Inn & Suites Easley - Greenville

Days Inn by Wyndham Easley/Greenville/Clemson Area

2.0 star property
6.2 out of 10, (724)
"The remote didn't work ask for batteries still didn't work no do not disturb ask for one don't have any tell them didn't want service did it anyway and didn't leave any towels all and all beds slept good nice and quiet everything was near by "
The price is SAR 261
SAR 290 total
includes taxes & fees
20 Apr - 21 Apr
Days Inn by Wyndham Easley/Greenville/Clemson Area

Hampton Inn Anderson/ Alliance Business Park

2.5 star property
9.2 out of 10, Wonderful, (748)
"The young man at the front desk needs more training. "
The price is SAR 436
SAR 484 total
includes taxes & fees
11 May - 12 May
Hampton Inn Anderson/ Alliance Business Park

Holiday Inn Express Anderson by IHG

2.5 star property
8.6 out of 10, Excellent, (363)
"Easy transaction. Great customer service."
The price is SAR 419
SAR 465 total
includes taxes & fees
18 Apr - 19 Apr
Holiday Inn Express Anderson by IHG

The Bleckley Inn

3.5 star property
9.8 out of 10, Exceptional, (394)
"Such a quaint nice hotel. Charm, cleanliness, location, convenience, staff all so good. Only negative was mattress was very uncomfortable and quite ‘springy and squeaky when sitting or turning over. "
The price is SAR 694
SAR 770 total
includes taxes & fees
22 Apr - 23 Apr
The Bleckley Inn

Home2 Suites by Hilton Anderson Downtown

3.0 star property
9.2 out of 10, Wonderful, (160)
"Beautiful new hotel. Our room is spacious with lots of drawers, counter space, and closet for luggage. Lots of thoughtfully-placed electrical outlets for plus, device charging, etc. Bright bathroom, very clean. Overall, great little place to stay."
The price is SAR 537
SAR 596 total
includes taxes & fees
20 Apr - 21 Apr
Home2 Suites by Hilton Anderson Downtown

Horizon Inn & Suites

2.0 star property
5.0 out of 10, (131)
"It was all around a nice stay with the exception of there was no remote or shower curtain"
The price is SAR 217
SAR 252 total
includes taxes & fees
15 Apr - 16 Apr
Horizon Inn & Suites

Super 8 by Wyndham Anderson/Clemson Area

2.5 star property
6.6 out of 10, (210)
"Very friendly and clean"
The price is SAR 263
SAR 292 total
includes taxes & fees
29 Apr - 30 Apr
Super 8 by Wyndham Anderson/Clemson Area

Quality Inn Clemson near University

2.5 star property
7.0 out of 10, Good, (821)
"Enjoyed my stay, however there isn't a channel list for the TV so you have to search around for something to watch. "
The price is SAR 264
SAR 293 total
includes taxes & fees
22 Apr - 23 Apr
Quality Inn Clemson near University

Holiday Inn Anderson by IHG

3.0 star property
8.8 out of 10, Excellent, (639)
"I would have expected for the room rate that it should have included breakfast. Otherwise we enjoyed our stay."
The price is SAR 484
SAR 538 total
includes taxes & fees
18 Apr - 19 Apr
Holiday Inn Anderson by IHG

Americas Best Value Inn Anderson, SC

2.0 star property
5.6 out of 10, (133)
"Stay here few times an love it. Clean friendly an quiet"
The price is SAR 252
SAR 280 total
includes taxes & fees
1 May - 2 May
Americas Best Value Inn Anderson, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Seneca

Escape to Seneca! Enjoy its sports, lake views, and coffee.

View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.
Photo by Cindy Keese
Open Photo by Cindy Keese

Frequently asked questions

Where is the best place for a stay in Seneca?

Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 5-minute walk from Lake Hartwell, and it offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.

What's the top vacation rental in Seneca?

3 Bedroom/2 Full Bath House in Seneca, SC. 4 miles from Clemson Campus!: Visitors give good reviews to this Seneca vacation home rental, which is equipped with a selection of games, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Some other homes for rent in Seneca include 4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake. and Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub. See all vacation rentals in Seneca.

If I need to cancel my hotel reservation in Seneca, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.

Where can I learn more about changing or cancelling my trip to Seneca?

To find more details about updating your trip to Seneca or cancelling it, click here.

What's the best place to stay for a family vacation to Seneca?

Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.

What's the best LGBTQ-friendly place to stay in Seneca?

Tru by Hilton Seneca Clemson is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn & Suites Seneca-Clemson Area is another good choice for your stay.

What's the best pet-friendly accommodation in Seneca?

Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Tru by Hilton Seneca Clemson and Days Inn by Wyndham Seneca / Clemson Area. See more pet-friendly hotel accommodations in Seneca.

What are some hotels with pools in Seneca?

Lakeside Lodge Clemson: Hotel, 7-minute walk from Lake Hartwell. Features free self parking, a seasonal outdoor pool, and complimentary wireless internet access. Quality Inn Seneca US-123 and Best Western Seneca-Clemson are two additional hotels with an onsite pool. View all hotels with pools in Seneca.

What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?

Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.

What is staying in Seneca like?

Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 277 hotels and other accommodations to choose from. Find out more about Seneca.

What should I do while I'm visiting Seneca?

Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee, and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.

What's the weather like in Seneca?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.