Find Resorts & Hotels with Spas in St. Charles, MO
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on St. Charles Resorts & Hotels with Spas
Tonight
Tomorrow
Next weekend
In two weeks
Compare St. Charles Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
8.8 out of 10, Excellent, (1137)
The price is SAR 520
SAR 597 total
includes taxes & fees
18 May - 19 May

Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
9.6 out of 10, Exceptional, (1002)
The price is SAR 413
SAR 478 total
includes taxes & fees
18 May - 19 May

Tru by Hilton St. Charles St. Louis, MO
Tru by Hilton St. Charles St. Louis, MO
8.6 out of 10, Excellent, (694)
The price is SAR 411
SAR 477 total
includes taxes & fees
18 May - 19 May

Hampton Inn & Suites St. Charles Old Town Area
Hampton Inn & Suites St. Charles Old Town Area
9.0 out of 10, Wonderful, (515)
The price is SAR 395
SAR 477 total
includes taxes & fees
25 May - 26 May

Best Western Plus The Charles Hotel
Best Western Plus The Charles Hotel
8.0 out of 10, Very Good, (1007)
The price is SAR 327
SAR 379 total
includes taxes & fees
12 May - 13 May

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
5.8 out of 10, (1001)
The price is SAR 338
SAR 391 total
includes taxes & fees
18 May - 19 May

Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St Louis
8.6 out of 10, Excellent, (902)
The price is SAR 316
SAR 363 total
includes taxes & fees
18 May - 19 May

Sleep Inn & Suites
Sleep Inn & Suites
5.8 out of 10, (448)
The price is SAR 286
SAR 329 total
includes taxes & fees
26 May - 27 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about St. Charles
Find out more about St. Charles
Recent reviews of St. Charles hotels
Recent reviews of St. Charles hotels

Hyatt Regency St. Louis at The Arch
5/5 Excellent
"Everything about my experience was fantastic! The dinner offerings were delicious and set a great tone for the day. Parking was easy and hassle-free, which is always a plus. The hotel itself is modern and clean, creating a welcoming atmosphere. There’s plenty of shopping and stores nearby, making it convenient for any last-minute needs. Access to local attractions was phenomenal, making my trip even more enjoyable. I would give this hotel ten stars if I could!
Highly recommended for anyone looking for a comfortable and convenient stay!"
A verified traveler stayed at Hyatt Regency St. Louis at The Arch
Posted 12 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Top neighborhoods for Resorts & Hotels with Spas
Find More Hotels near St. Charles
More Hotel Options in St. Charles
- Adventure Hotels in St. Charles
- Business Hotels in St. Charles
- Casinos in St. Charles
- Cheap Hotels in St. Charles
- Family Hotels in St. Charles
- Golf Hotels in St. Charles
- Historic Hotels in St. Charles
- Hotel Wedding Venues in St. Charles
- Hotel with a Concierge in St. Charles
- Hotels with Bars in St. Charles
- Hotels with Free Parking in St. Charles
- Hotels with Hot Tubs in St. Charles
- Hotels with WiFi in St. Charles
- Hotels with a Pool in St. Charles
- Hotels with an Indoor Pool in St. Charles
- Hotels with smoking rooms in St. Charles
- Luxury Hotels in St. Charles
- Pet-friendly Hotels in St. Charles
- Romantic Hotels in St. Charles
- Shopping Hotels in St. Charles
- Winery Hotels in St. Charles
Hotels near popular St. Louis Attractions
- Hotels near Ameristar Casino St. Charles
- Hotels near St Charles Convention Center
- Hotels near Lindenwood University
- Hotels near Historic Main Street
- Hotels near Family Arena
- Hotels near Fast Lane Classic Cars
- Hotels near Katy Trail
- Hotels near Lewis & Clark Boathouse and Nature Center
- Hotels near Missouri Bluffs Golf Course
- Hotels near First Missouri State Capitol Historic Site
St. Charles Hotels by Star Rating
Explore more hotels
- Clayton Plaza Hotel & Extended Stay
- Pear Tree Inn St. Louis Airport
- River City Casino & Hotel
- Sonesta ES Suites St. Louis - Chesterfield
- Pear Tree Inn St. Louis Near Union Station
- Best Western St. Louis-Kirkwood Route 66
- Hilton St. Louis Airport
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- 21C Museum Hotel St Louis
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Live by Loews - St.Louis
- Moonrise Hotel
- Renaissance St. Louis Airport Hotel
- Hilton St. Louis at the Ballpark
- Casino Queen Hotel
- Hilton Pennywell St. Louis at the Arch
- Embassy Suites by Hilton St. Louis Downtown
- Forest Park Hotel by MDR
- Marriott St. Louis Grand
- Wingate by Wyndham St. Louis/Fenton Route 66