Find Luxury Hotels in St. Charles, MO

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Pick from 6 St. Charles Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Ameristar Casino Resort and Spa
4.5 star property
8.2 out of 10, Very Good, (1002)
"Great experience. However the room was a little warmer than what we're used to. We tried to cool it down, but was unsuccessful. "
The price is SAR 636
SAR 805 total
includes taxes & fees
25 Nov - 26 Nov
Ameristar Casino Resort and Spa
Country Inn & Suites by Radisson, St. Charles, MO
2.5 star property
9.4 out of 10, Exceptional, (1000)
"Beautiful area "
The price is SAR 373
SAR 420 total
includes taxes & fees
1 Dec - 2 Dec
Country Inn & Suites by Radisson, St. Charles, MO
Relax Inn Saint Charles
2.0 star property
6.2 out of 10, (726)
"Was scared but it was actually totally fine! "
The price is SAR 224
SAR 257 total
includes taxes & fees
15 Nov - 16 Nov
Relax Inn Saint Charles
Baymont by Wyndham St. Charles
2.5 star property
8.0 out of 10, Very Good, (965)
"My bed is clean and comfy! I always love that hotel use all white beddings and overall the room is clean and tidy. The area in St Charles is what makes me decide to stay here. Very safe and quiet. "
The price is SAR 256
SAR 288 total
includes taxes & fees
20 Nov - 21 Nov
Baymont by Wyndham St. Charles
Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
8.8 out of 10, Excellent, (1152)
"Stayed one night. "
The price is SAR 476
SAR 539 total
includes taxes & fees
25 Nov - 26 Nov
Embassy Suites by Hilton St. Louis St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 5 restaurants and 2 bars, and it’s a popular choice for Expedia travelers looking for an elegant place to stay.
How many luxury hotels can I expect to find in St. Charles?
Lie in the lap of luxury during your getaway to St. Charles in one of Expedia’s 6 luxury hotels.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you’re in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail, and St Charles Convention Center. If you have a little extra time during your trip, you might want to make a stop at Ameristar Casino St. Charles and Fast Lane Classic Cars.