Find Luxury Hotels in St. Charles, MO

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on St. Charles Luxury Hotels

Compare St. Charles Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Ameristar Casino Resort and Spa
Casino

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very Good, (1006)
"Was a great stay. View on the river side during winter is meh.... Best thing for view was at night seeing the mass amount of traffic going over the bridge. Food options.... amazing!!! If you go to a show at The Rize, dont expect the main act to go on until 1 am."
The price is SAR 634
SAR 804 total
includes taxes & fees
9 Mar - 10 Mar
Ameristar Casino Resort and Spa
Country Inn & Suites by Radisson, St. Charles Historic District
Desk, laptop workspace, blackout drapes, iron/ironing board

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
9.4 out of 10, Exceptional, (1006)
"The property is close to dining, shopping and exploring "
The price is SAR 395
SAR 454 total
includes taxes & fees
9 Mar - 10 Mar
Country Inn & Suites by Radisson, St. Charles Historic District
Relax Inn Saint Charles
Lobby

Relax Inn Saint Charles

2.0 star property
6.4 out of 10, (786)
"I like that it’s peaceful "
The price is SAR 236
SAR 272 total
includes taxes & fees
4 Mar - 5 Mar
Relax Inn Saint Charles
Baymont by Wyndham St. Charles
Lobby

Baymont by Wyndham St. Charles

2.5 star property
8.0 out of 10, Very Good, (1006)
"Clean room but definitely needs to be updated"
The price is SAR 273
SAR 313 total
includes taxes & fees
23 Mar - 24 Mar
Baymont by Wyndham St. Charles
Embassy Suites by Hilton St. Louis St. Charles
Lobby

Embassy Suites by Hilton St. Louis St. Charles

3.5 star property
8.8 out of 10, Excellent, (1174)
"Good stay. Staff was nice. Breakfast was a bit institutional with frozen waffles and pancakes but was ok "
The price is SAR 475
SAR 546 total
includes taxes & fees
30 Mar - 31 Mar
Embassy Suites by Hilton St. Louis St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in St. Charles

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it’s a popular choice for Expedia travelers looking for an elegant place to stay.
How many luxury hotels can I expect to find in St. Charles?
Lie in the lap of luxury during your getaway to St. Charles in one of Expedia’s 6 luxury hotels.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you’re in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail, and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.