Find Luxury Hotels in St. Charles, MO

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Compare St. Charles Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Ameristar Casino Resort and Spa
Exterior

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very Good, (1001)
"Really enjoyed the stay ALL was great, the slots were tight though.......never won and we definitely tried. Need more $5 minimum tables, rediculous. Use your brains marketing people 😜"
The price is SAR 635
SAR 805 total
includes taxes & fees
8 Jan - 9 January 2025
Ameristar Casino Resort and Spa
Country Inn & Suites by Radisson, St. Charles Historic District
Exterior

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
9.4 out of 10, Exceptional, (1002)
"Excellent Stay!"
The price is SAR 364
SAR 418 total
includes taxes & fees
29 Dec - 30 Dec
Country Inn & Suites by Radisson, St. Charles Historic District
Relax Inn Saint Charles
Lobby

Relax Inn Saint Charles

2.0 star property
6.4 out of 10, (747)
"The person checking me in was kind and the process was fast "
The price is SAR 223
SAR 257 total
includes taxes & fees
30 Dec - 31 Dec
Relax Inn Saint Charles
Baymont by Wyndham St. Charles
Room

Baymont by Wyndham St. Charles

2.5 star property
8.0 out of 10, Very Good, (1003)
"I have an autistic 5yrld & always worry about noise complaints as shes a sensory seeker & can be quite loud & as well as energetic, especially after a long drive. I made sure to tell the front staff desk about her & to please let me know if anyone says she's too loud. The night worker on Christmas eve was extremely understanding and very polite as well as efficient any time we needed anything. I had that same experience on Christmas morning with the breakfast staff as well as the cleaning...
The price is SAR 256
SAR 294 total
includes taxes & fees
1 Jan - 2 January 2025
Baymont by Wyndham St. Charles
Embassy Suites by Hilton St. Louis St. Charles
Exterior

Embassy Suites by Hilton St. Louis St. Charles

3.5 star property
8.8 out of 10, Excellent, (1156)
"Great stay!"
The price is SAR 463
SAR 532 total
includes taxes & fees
26 Jan - 27 January 2025
Embassy Suites by Hilton St. Louis St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it’s a popular choice for Expedia travelers looking for an elegant place to stay.
How many luxury hotels can I expect to find in St. Charles?
Lie in the lap of luxury during your getaway to St. Charles in one of Expedia’s 6 luxury hotels.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you’re in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail, and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.