Photo by Geraldine Soh
Find hotels near Historic Main Street, St. Louis from SAR 270
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Compare 468 hotels close to Historic Main Street with room rates, reviews, and availability. Most hotels are fully refundable.

Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District
9.4 out of 10, Exceptional, (1003)
The price is SAR 427
SAR 491 total
includes taxes & fees
23 Mar - 24 Mar

Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
9.6 out of 10, Exceptional, (1007)
The price is SAR 413
SAR 478 total
includes taxes & fees
30 Mar - 31 Mar

Hampton Inn & Suites St. Charles Old Town Area
Hampton Inn & Suites St. Charles Old Town Area
9.0 out of 10, Wonderful, (495)
The price is SAR 439
SAR 527 total
includes taxes & fees
6 Apr - 7 Apr

Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St Louis
8.6 out of 10, Excellent, (865)
The price is SAR 316
SAR 363 total
includes taxes & fees
30 Mar - 31 Mar

Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
8.8 out of 10, Excellent, (1168)
The price is SAR 503
SAR 578 total
includes taxes & fees
30 Mar - 31 Mar

Tru by Hilton St. Charles St. Louis, MO
Tru by Hilton St. Charles St. Louis, MO
8.6 out of 10, Excellent, (679)
The price is SAR 443
SAR 514 total
includes taxes & fees
30 Mar - 31 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels near Other St. Louis Attractions
Hotels near Other St. Louis Attractions
First Missouri State Capitol Historic Site
4/5(2 reviews)
You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and great live music in this family-friendly area.
Recent reviews of Historic Main Street hotels
Recent reviews of Historic Main Street hotels

Country Inn & Suites by Radisson, St. Charles Historic District
5/5 Excellent
"Perfect location right on Katy trail and downtown St Charles"
A verified traveler stayed at Country Inn & Suites by Radisson, St. Charles Historic District
Posted 2 days ago
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Hotels near popular St. Louis Attractions
- Hotels near First Missouri State Capitol Historic Site
- Hotels near Ameristar Casino St. Charles
- Hotels near Hollywood Casino Amphitheatre
- Hotels near Mississippi River
- Hotels near Westport Plaza
- Hotels near St Charles Convention Center
- Hotels near Hollywood Casino
- Hotels near Lindenwood University
- Hotels near Missouri River
- Hotels near Saint Louis Galleria Mall
- Hotels near Family Arena
- Hotels near The Loop
- Hotels near Centene Community Ice Center
- Hotels near St. Louis Premium Outlets
- Hotels near Lou Fusz Soccer Complex
- Hotels near The Factory
- Hotels near Katy Trail
- Hotels near Fast Lane Classic Cars
- Hotels near Chesterfield Sports Fusion
- Hotels near Mid Rivers Mall
Hotels in top St. Charles Historic District neighborhoods
Other Hotels near Historic Main Street, St. Charles Historic District
- St. Charles Hotels
- Maryland Heights Hotels
- Chesterfield Hotels
- O'Fallon Hotels
- Hazelwood Hotels
- St. Peters Hotels
- Alton Hotels
- Fenton Hotels
- Ozarks Hotels
- Wentzville Hotels
- Richmond Heights Hotels
- Kirkwood Hotels
- Grafton Hotels
- Brentwood Hotels
- Southern Illinois Hotels
- Bridgeton Hotels
- Wildwood Hotels
- Eureka Hotels
- Florissant Hotels
- Granite City Hotels
More Hotel Options in Historic Main Street
- Adventure Hotels
- Business Hotels
- Casinos
- Cheap Hotels
- Family Hotels
- Golf Hotels
- Historic Hotels
- Hotel Wedding Venues
- Hotel with a Concierge
- Hotels with Bars
- Hotels with Free Parking
- Hotels with Hot Tubs
- Hotels with WiFi
- Hotels with a Pool
- Hotels with an Indoor Pool
- Luxury Hotels
- Resorts & Hotels with Spas
- Romantic Hotels
- Shopping Hotels
- Winery Hotels
Explore more hotels
- Western-Themed 2-Bedroom Hideout for Outlaws 204-2
- The Historic Bricks on Main
- The Lofts of North Main Street
- 3BR Historic St. Charles, MO-Walking distance to Main Street
- Walking distance to Historic Main Street, St. Charles, MO
- St. Charles Victorian Gem | Steps to Main Street
- Prime Loft of Main Street
- Stay on Historic Main!
- The Wild Rose Cottage in Historic Old St Charles
- Main Street Balcony Apartment by StayLage!
- 🌷RARE NEW TREASURE🌷2 Homes+Outdoor Gathering Area. Two Blocks From Main St.!!!
- Amazing Renovated Historic Loft on Main Street