Search Vacation Homes in Southeast Missouri

"When looking for a VRBO for our daughter's college visit, we knew the perfect place to stay! This is our second stay at Serenity South and it was just as incredible as the first visit. Clean, inviting and cozy. Thanks Jo for another beautiful stay."

"This was a great option if you’re staying in the area. Great communication with the owner, all the appointments you need. Great (very very small) town but again all you need. Be sure to get coffee from Acadia and Mexican at el Checo’s. Only thing I’d note is the upstairs bathroom is bathtub only which is clearly called out in the description but just want to be sure folks saw that. Highly recommended if you’re needing a great place in Ironton. "

"We were there for our grandson's wedding. This little house exceeded all expectation. Just lovely and with so many extra thoughtful touches, i.e. pumpkins and fall flowers for cozy October. Too many to list. "

"This house was a home!! Decorated for Christmas including a tree!! Nice blankets in the living room to cuddle up with plus an electric fireplace!! Loved every minute of it. Host has it well stocked with coffee supplies, shower soaps and shampoo best of all laundry doap and dryer sheets"

"Amazing property that we simply didn't stay long enough to enjoy in its completeness. Billiards and Putt-Putt on entry, so attractive that we started playing before we even unpacked! I'm very artsy interior, and lots of room and outdoor fire pit, multiple decks, and an in-ground pool. The home is even on the grounds, an event venue. Probably a wonderful combination for them! Would enjoy returning, but for a longer stay will you could enjoy all with the property had to offer! Highly recommend it"

"We chose this property for our 1st Christmas away from home. I traveled with my husband, 3 kids aged 10-17, and 2 dogs. Walking in the first thing we saw was the beautiful Christmas tree and the decorated screened in porch. The home was very clean and had everything we could possibly need. The furniture was comfy and there were plenty of places for everyone to sit and relax. The bedrooms were spacious. The closets provided more than enough space to hang the clothes we brought with us. These...

"The house has a very eclectic decor, but fun. We were a group of 10 ladies and had a great time. Thank you "

"We were there for a family funeral. There was virtual nothing wrong with the home. I am persnickety do I did notice a spot on the hallway floor. My sister did not. I didn’t check it or try to clean it. I just went in with the events of the day. We had tornado warnings and there were zero issues. Again, I don’t think we can say enough regarding the graciousness of our hosts. I would highly recommend this home. "