Search Motels in Southeast Missouri
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Next weekend
In two weeks
In one month
In two months
Compare 26 Motels in Southeast Missouri with updated reviews, rates, and availability.

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO
8.0 out of 10, Very Good, (1005)
The price is SAR 296
SAR 313 total
includes taxes & fees
22 Apr - 23 Apr

New Orleans Inn Portageville
New Orleans Inn Portageville
8.2 out of 10, Very Good, (649)
The price is SAR 213
SAR 230 total
includes taxes & fees
27 Apr - 28 Apr

Super 8 by Wyndham Perryville
Super 8 by Wyndham Perryville
8.4 out of 10, Very Good, (845)
The price is SAR 265
SAR 303 total
includes taxes & fees
4 May - 5 May

Super 8 by Wyndham Farmington
Super 8 by Wyndham Farmington
8.0 out of 10, Very Good, (528)
The price is SAR 226
SAR 258 total
includes taxes & fees
22 Apr - 23 Apr

Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
6.0 out of 10, (178)
The price is SAR 236
SAR 276 total
includes taxes & fees
1 May - 2 May

Super 8 by Wyndham Bonne Terre
Super 8 by Wyndham Bonne Terre
6.8 out of 10, (457)
The price is SAR 191
SAR 209 total
includes taxes & fees
27 Apr - 28 Apr

Super 8 by Wyndham Potosi
Super 8 by Wyndham Potosi
7.0 out of 10, Good, (346)
The price is SAR 198
SAR 216 total
includes taxes & fees
4 May - 5 May

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
6.6 out of 10, (550)
The price is SAR 247
SAR 274 total
includes taxes & fees
4 May - 5 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Other property types in Southeast Missouri

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
9.4 out of 10, Exceptional, (140)
The price is SAR 597
SAR 688 total
includes taxes & fees
28 Apr - 29 Apr

Postcard Cabins St. Francois
Postcard Cabins St. Francois
10.0 out of 10, Exceptional, (3)
The price is SAR 338
SAR 505 total
includes taxes & fees
4 May - 5 May

Springside Cottage in beautiful Eminence. Great outdoor space - NEW Hot tub!
Springside Cottage in beautiful Eminence. Great outdoor space - NEW Hot tub!
10.0 out of 10, Exceptional, (2)
The price is SAR 713
SAR 841 total
includes taxes & fees
22 Apr - 23 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Southeast Missouri hotels
Recent reviews of Southeast Missouri hotels

The Riverview
5/5 Excellent
"Very beautiful and clean! Casino was fun!!!"
A verified traveler stayed at The Riverview
Posted 1 day ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Popular Destinations
- Motels in Cape Girardeau
- Motels in Eminence
- Motels in Van Buren
- Motels in Jackson
- Motels in Dexter
- Motels in Poplar Bluff
- Motels in Perryville
- Motels in Fredericktown
- Motels in Bonne Terre
- Motels in Festus
- Motels in Ironton
- Motels in Sikeston
- Motels in Potosi
- Motels in Hayti
- Motels in Ste Genevieve
- Motels in Farmington
Top Motels in Other Destinations
More Accommodation Types in Southeast Missouri
- Vacation Homes in Southeast Missouri
- Cabin Rentals in Southeast Missouri
- Cottages in Southeast Missouri
- Apartments in Southeast Missouri
- Farmstay in Southeast Missouri
- RV Parks in Southeast Missouri
- Lodges in Southeast Missouri
- Condo Rentals in Southeast Missouri
- Aparthotels in Southeast Missouri
- B&B in Southeast Missouri
- Villas in Southeast Missouri
- Hotels