Photo by Cindy Keese

Search Vacation Homes in Seneca

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Next weekend
11 Rab. II - 13 Rab. II
In two weeks
18 Rab. II - 20 Rab. II
In one month
2 Jum. I - 4 Jum. I
In two months
30 Jum. I - 1 Jum. II

Compare 715 Vacation Homes in Seneca with updated reviews, rates, and availability.

Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson
Property grounds

Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson

10.0 out of 10, Exceptional, (76)
"Rented for a HS fishing tournament, the driveway and road setup is perfect! "
Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson
Young@Hart is a Lakefront home w/ Covered Dock, Game Room, 4 Kayaks & Hot Tub!!
Terrace/patio

Young@Hart is a Lakefront home w/ Covered Dock, Game Room, 4 Kayaks & Hot Tub!!

10.0 out of 10, Exceptional, (79)
"Everything was great"
Young@Hart is a Lakefront home w/ Covered Dock, Game Room, 4 Kayaks & Hot Tub!!
Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath
Terrace/patio

Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath

10.0 out of 10, Exceptional, (63)
"relaxing on porch"
Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath
Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger
Fridge, microwave, oven, stovetop

Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

9.8 out of 10, Exceptional, (115)
"We had a great stay in this wonderful home! This house was very clean, well equipped, had comfortable beds, and great living spaces! The view was beautiful and the driveway, while steep, had plenty of parking and turn around space for 2 minivans. My friend and I brought our daughters to watch a Clemson gymnastics meet and then spend some time together after. This house was perfect for our group! It had everything we needed to cook dinner and breakfast the next morning. The girls had so much fun...
The price is SAR 1,500
SAR 2,806 total
includes taxes & fees
2 Apr - 3 Apr
Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger
Great weekend getaway just a mile from downtown!
Fridge, microwave, oven, stovetop

Great weekend getaway just a mile from downtown!

10.0 out of 10, Exceptional, (10)
"Host was very kind and quick to respond. Great location. Will definitely check here again whenever booking in the future."
Great weekend getaway just a mile from downtown!
The Brick House At Currahee
Fridge, microwave, oven, stovetop

The Brick House At Currahee

9.6 out of 10, Exceptional, (53)
"Reminds me of grandma's house. Lots of antiques decor. Very cozy and very clean"
The price is SAR 398
SAR 753 total
includes taxes & fees
3 Apr - 4 Apr
The Brick House At Currahee
Clemson House 1 mile from University & Stadium!
3 bedrooms, desk, iron/ironing board, free WiFi

Clemson House 1 mile from University & Stadium!

9.4 out of 10, Exceptional, (14)
"Came to visit my daughter at Clemson for the weekend. The house was close to campus. Easy check in and out and perfect for what we needed. Would stay here again!"
The price is SAR 675
SAR 1,432 total
includes taxes & fees
2 Apr - 3 Apr
Clemson House 1 mile from University & Stadium!
Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.
Fridge, microwave, oven, stovetop

Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.

10.0 out of 10, Exceptional, (16)
"Great location and my dogs loved being there with us. House was perfect and clean. Definitely going back!"
Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.
Guesthouse located in historic Toccoa Ga
Exterior detail

Guesthouse located in historic Toccoa Ga

10.0 out of 10, Exceptional, (24)
"This little home away from home was wonderful ♥️ Owners were amazing and very helpful. Very spacious and open. We will definitely be making a return trip🎉"
Guesthouse located in historic Toccoa Ga
Lake Hartwell Waterfront, Dock, Clemson, Fire Pit, Fenced Yard, Pets & Game Room
Smart TV, fireplace, books, music library

Lake Hartwell Waterfront, Dock, Clemson, Fire Pit, Fenced Yard, Pets & Game Room

10.0 out of 10, Exceptional, (101)
"The moment we arrived it felt like we were already home. This place is a piece of heaven on earth."
Lake Hartwell Waterfront, Dock, Clemson, Fire Pit, Fenced Yard, Pets & Game Room
North Keowee Family Lake House on Private Cove With Dock / 5 MIN FROM JOCASSEE
Miscellaneous

North Keowee Family Lake House on Private Cove With Dock / 5 MIN FROM JOCASSEE

10.0 out of 10, Exceptional, (102)
"Nice home with lots of room to spread out - large sunroom with TV, beautiful screened porch with comfortable seating and TV, and adequate living room for a small group. Dining table seats eight. Upstairs there are two large bunk rooms and a king bedroom but only one bathroom. Nice dock and porch for watching sunset. Enjoyed the fire pit."
North Keowee Family Lake House on Private Cove With Dock / 5 MIN FROM JOCASSEE
Cute House on Lake Hartwell- Dock Access! PETS ALLOWED!
Terrace/patio

Cute House on Lake Hartwell- Dock Access! PETS ALLOWED!

Cute House on Lake Hartwell- Dock Access! PETS ALLOWED!
Keowee Key Condo w/ Lake Access & Community Pools!
Aerial view

Keowee Key Condo w/ Lake Access & Community Pools!

2.0 star property
10.0 out of 10, Exceptional, (5)
"The condo was perfect. Large, clean, and well equipped. The location was quiet and convenient. "
Keowee Key Condo w/ Lake Access & Community Pools!
Cozy House on the way to Clemson, Pendleton, Anderson and T. Ed Garrison Arena
Exterior

Cozy House on the way to Clemson, Pendleton, Anderson and T. Ed Garrison Arena

2.0 star property
9.6 out of 10, Exceptional, (4)
"This place is a fantastic stay!"
Cozy House on the way to Clemson, Pendleton, Anderson and T. Ed Garrison Arena
Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub
Outdoor spa tub

Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub

10.0 out of 10, Exceptional, (138)
"This house was perfect for a weekend getaway with 7 adults and 7 kids between the ages of 3-11. Beautiful view, spacious, stocked kitchen, quiet neighborhood, fun hot tub!"
Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
Property grounds

Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock

9.6 out of 10, Exceptional, (161)
"Beautiful spot at the end of a quiet road with water access. Cozy property that could accomodate a large family. Very comfortable and relaxing"
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub
Exterior

Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub

10.0 out of 10, Exceptional, (44)
"Everything was great! Plenty of space for large gatherings or for smaller groups, or even to get some quiet alone time. Lots of games and activities available. "
Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub
Lakehouse Retreat with dock, paddle boat, canoe & kayaks!
Terrace/patio

Lakehouse Retreat with dock, paddle boat, canoe & kayaks!

10.0 out of 10, Exceptional, (165)
"This place was great for our whole family. It was stocked with everything we needed for our stay. Could not have been happier. "
Lakehouse Retreat with dock, paddle boat, canoe & kayaks!
NEW! Beautiful 5 bedroom Lake Keowee Cove Home!
Fridge, microwave, oven, stovetop

NEW! Beautiful 5 bedroom Lake Keowee Cove Home!

9.4 out of 10, Exceptional, (8)
"We had the Best time at this home! The home was 2 storied with a door that separated the 2 living areas. Upstairs the adults could relax quietly by the inside fire, sit out on the porch and serve up the meals. Downstairs the college aged kids could hang out, play games or sit by the outdoor fire pit. There was so much to do at the home! Best part: Close to Clemson!! "
NEW! Beautiful 5 bedroom Lake Keowee Cove Home!
Lake Front, Quiet, Private cove on 4.75 acres, Canoe, 2 Kayak, 2 boat docks
Property grounds

Lake Front, Quiet, Private cove on 4.75 acres, Canoe, 2 Kayak, 2 boat docks

10.0 out of 10, Exceptional, (217)
"Excellent host and lovely place."
Lake Front, Quiet, Private cove on 4.75 acres, Canoe, 2 Kayak, 2 boat docks
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Seneca
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Other property types in Seneca

Postcard Cabins Lake Hartwell
Exterior

Postcard Cabins Lake Hartwell

2.0 star property
10.0 out of 10, Exceptional, (4)
"This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?"
The price is SAR 338
SAR 371 total
includes taxes & fees
15 Apr - 16 Apr
Postcard Cabins Lake Hartwell
Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub
Exterior

Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub

10.0 out of 10, Exceptional, (44)
"Everything was great! Plenty of space for large gatherings or for smaller groups, or even to get some quiet alone time. Lots of games and activities available. "
Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub
Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
Lake

Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!

9.8 out of 10, Exceptional, (45)
"We had a small group for a relaxing weekend away for my nieces sweet 16. They really enjoyed the kayaks and wild life around the property. We all enjoyed the peaceful area and the ability to have safe family and friend time. I will definitely be back for another relaxing getaway. "
Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.