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Check prices for these dates

Compare 715 Vacation Homes in Seneca with updated reviews, rates, and availability.

Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson

10.0 out of 10, Exceptional, (76)
"Rented for a HS fishing tournament, the driveway and road setup is perfect! "
Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson

Young@Hart is a Lakefront home w/ Covered Dock, Game Room, 4 Kayaks & Hot Tub!!

10.0 out of 10, Exceptional, (79)
"Everything was great"
Young@Hart is a Lakefront home w/ Covered Dock, Game Room, 4 Kayaks & Hot Tub!!

Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath

10.0 out of 10, Exceptional, (63)
"The house is very spacious and a great layout. The location is perfect. The kids enjoyed the arcade games and the basketball. We had a great time. We hope to come back soon. "
Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath

Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

9.8 out of 10, Exceptional, (115)
"We had a great stay in this wonderful home! This house was very clean, well equipped, had comfortable beds, and great living spaces! The view was beautiful and the driveway, while steep, had plenty of parking and turn around space for 2 minivans. My friend and I brought our daughters to watch a Clemson gymnastics meet and then spend some time together after. This house was perfect for our group! It had everything we needed to cook dinner and breakfast the next morning. The girls had so much fun...
The price is SAR 1,407
SAR 2,674 total
includes taxes & fees
28 Mar - 29 Mar
Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

Great weekend getaway just a mile from downtown!

10.0 out of 10, Exceptional, (10)
"We weren’t there much. We slept and showered not much else at the house. I did enjoy the rockers on the back porch. Everything was comfortable. I would stay again. "
Great weekend getaway just a mile from downtown!

The Brick House At Currahee

9.6 out of 10, Exceptional, (53)
"Reminds me of grandma's house. Lots of antiques decor. Very cozy and very clean"
The price is SAR 398
SAR 757 total
includes taxes & fees
27 Mar - 28 Mar
The Brick House At Currahee

Clemson House 1 mile from University & Stadium!

9.4 out of 10, Exceptional, (14)
"Came to visit my daughter at Clemson for the weekend. The house was close to campus. Easy check in and out and perfect for what we needed. Would stay here again!"
The price is SAR 675
SAR 1,437 total
includes taxes & fees
21 Apr - 22 Apr
Clemson House 1 mile from University & Stadium!

Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.

10.0 out of 10, Exceptional, (16)
"Great location and my dogs loved being there with us. House was perfect and clean. Definitely going back!"
Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.

Guesthouse located in historic Toccoa Ga

10.0 out of 10, Exceptional, (24)
"This property was very well appointed and furnished. It was quiet, comfortable and had plenty of room for the three of us. The laundry facilities were excellent and easy to use. The bathrooms were wonderful, plenty of towels and the master bedroom was warm and inviting. Great place for a getaway!"
Guesthouse located in historic Toccoa Ga

Lake Hartwell Waterfront, Dock, Clemson, Fire Pit, Fenced Yard, Pets & Game Room

10.0 out of 10, Exceptional, (101)
"The moment we arrived it felt like we were already home. This place is a piece of heaven on earth."
Lake Hartwell Waterfront, Dock, Clemson, Fire Pit, Fenced Yard, Pets & Game Room

North Keowee Family Lake House on Private Cove With Dock / 5 MIN FROM JOCASSEE

10.0 out of 10, Exceptional, (102)
"Nice home with lots of room to spread out - large sunroom with TV, beautiful screened porch with comfortable seating and TV, and adequate living room for a small group. Dining table seats eight. Upstairs there are two large bunk rooms and a king bedroom but only one bathroom. Nice dock and porch for watching sunset. Enjoyed the fire pit."
North Keowee Family Lake House on Private Cove With Dock / 5 MIN FROM JOCASSEE

Cute House on Lake Hartwell- Dock Access! PETS ALLOWED!

Cute House on Lake Hartwell- Dock Access! PETS ALLOWED!

Keowee Key Condo w/ Lake Access & Community Pools!

2.0 star property
10.0 out of 10, Exceptional, (5)
"Excellent stay in a welcoming townhouse! Owner provided excellent communication when needed. Will definitely stay again and recommend to any friends or family in the future!"
Keowee Key Condo w/ Lake Access & Community Pools!

Cozy House on the way to Clemson, Pendleton, Anderson and T. Ed Garrison Arena

2.0 star property
9.6 out of 10, Exceptional, (4)
"Joe, the homeowner, was extremely easy to contact and was very pleasant to work with. He is relatively new to the VRBO experience, but is very open minded to the little issues that we did contact him over. The house was perfectly located for our needs and located about midway to the Clemson campus and the city of Anderson where you find Sam's Club, Walmart and many other shopping centers."
Cozy House on the way to Clemson, Pendleton, Anderson and T. Ed Garrison Arena

Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub

10.0 out of 10, Exceptional, (138)
"This house was perfect for a weekend getaway with 7 adults and 7 kids between the ages of 3-11. Beautiful view, spacious, stocked kitchen, quiet neighborhood, fun hot tub!"
Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub

Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock

9.6 out of 10, Exceptional, (161)
"Beautiful spot at the end of a quiet road with water access. Cozy property that could accomodate a large family. Very comfortable and relaxing"
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock

Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub

10.0 out of 10, Exceptional, (44)
"Everything was great! Plenty of space for large gatherings or for smaller groups, or even to get some quiet alone time. Lots of games and activities available. "
Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub

Lakehouse Retreat with dock, paddle boat, canoe & kayaks!

10.0 out of 10, Exceptional, (165)
"This place was great for our whole family. It was stocked with everything we needed for our stay. Could not have been happier. "
Lakehouse Retreat with dock, paddle boat, canoe & kayaks!

NEW! Beautiful 5 bedroom Lake Keowee Cove Home!

9.4 out of 10, Exceptional, (8)
"We had the Best time at this home! The home was 2 storied with a door that separated the 2 living areas. Upstairs the adults could relax quietly by the inside fire, sit out on the porch and serve up the meals. Downstairs the college aged kids could hang out, play games or sit by the outdoor fire pit. There was so much to do at the home! Best part: Close to Clemson!! "
NEW! Beautiful 5 bedroom Lake Keowee Cove Home!

Lake Front, Quiet, Private cove on 4.75 acres, Canoe, 2 Kayak, 2 boat docks

10.0 out of 10, Exceptional, (217)
"Excellent host and lovely place."
Lake Front, Quiet, Private cove on 4.75 acres, Canoe, 2 Kayak, 2 boat docks
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Seneca

Postcard Cabins Lake Hartwell

2.0 star property
10.0 out of 10, Exceptional, (4)
"This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?"
The price is SAR 338
SAR 371 total
includes taxes & fees
9 Apr - 10 Apr
Postcard Cabins Lake Hartwell

Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub

10.0 out of 10, Exceptional, (138)
"This house was perfect for a weekend getaway with 7 adults and 7 kids between the ages of 3-11. Beautiful view, spacious, stocked kitchen, quiet neighborhood, fun hot tub!"
Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub

Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock

9.6 out of 10, Exceptional, (161)
"Beautiful spot at the end of a quiet road with water access. Cozy property that could accomodate a large family. Very comfortable and relaxing"
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.