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Compare 715 Vacation Homes in Seneca with updated reviews, rates, and availability.

Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson
Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson
10.0 out of 10, Exceptional, (77)

Young@Hart is a Lakefront home w/ Covered Dock, Game Room, 4 Kayaks & Hot Tub!!
Young@Hart is a Lakefront home w/ Covered Dock, Game Room, 4 Kayaks & Hot Tub!!
10.0 out of 10, Exceptional, (82)

Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath
Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath
10.0 out of 10, Exceptional, (63)

Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger
Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger
9.8 out of 10, Exceptional, (115)
The price is SAR 1,689
SAR 3,042 total
includes taxes & fees
29 Apr - 30 Apr

Great weekend getaway just a mile from downtown!
Great weekend getaway just a mile from downtown!
10.0 out of 10, Exceptional, (11)

The Brick House At Currahee
The Brick House At Currahee
9.6 out of 10, Exceptional, (53)
The price is SAR 398
SAR 761 total
includes taxes & fees
18 Apr - 19 Apr

Clemson House 1 mile from University & Stadium!
Clemson House 1 mile from University & Stadium!
9.4 out of 10, Exceptional, (14)
The price is SAR 563
SAR 1,291 total
includes taxes & fees
20 Apr - 21 Apr

Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.
Relaxed, pet-friendly home walkable to Clemson campus, stadiums or downtown.
10.0 out of 10, Exceptional, (17)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Seneca

Postcard Cabins Lake Hartwell
Postcard Cabins Lake Hartwell
10.0 out of 10, Exceptional, (4)
The price is SAR 338
SAR 516 total
includes taxes & fees
1 May - 2 May

3 Bedroom/2 Full Bath House in Seneca, SC. 4 miles from Clemson Campus!
3 Bedroom/2 Full Bath House in Seneca, SC. 4 miles from Clemson Campus!

Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub
Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub
10.0 out of 10, Exceptional, (44)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Seneca hotels
Recent reviews of Seneca hotels

Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
5/5 Excellent
Great weekend!
"I don’t think the beds were quite as advertised, but it worked out well for us, anyway. Great location! The driveway was quite steep and that was difficult for my elderly mother. We had two family members who couldn’t make the trip, and they would not have been able to park in the steep driveway. Otherwise, wonderful!!"
A verified traveler stayed at Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
Posted 2 days ago