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Compare 573 Vacation Homes in Seneca with updated reviews, rates, and availability.

2-209C - Coopers Cozy Cabin ^ Lake Hartwell ^ WIFI ^ Pets Welcome

9.6 out of 10, Exceptional, (66)
"My daughter and I, plus our two tiny dogs, had a wonderfully quiet and relaxing long weekend. The house is tiny but completely met our needs. The bed and living room furniture are comfy. We had one rainy day, but the roomy screened porch allowed us to enjoy the gentle rain. This is our 2nd stay at this house. We’d love to come back soon!"
2-209C - Coopers Cozy Cabin ^ Lake Hartwell ^ WIFI ^ Pets Welcome

Great weekend getaway just a mile from downtown!

10.0 out of 10, Exceptional, (8)
"The property is a great place to spend time with the family. Description is accurate. The host is very responsive and made our stay perfect. It is located close to almost everything. You can walk to the university within 15 minutes. Hiking trails are within a 10 minute drive."
Great weekend getaway just a mile from downtown!

GREAT RATES! Beautiful views on Lake Hartwell!!!!

10.0 out of 10, Exceptional, (72)
"If you're looking to get away and have a relaxing stay at the lake, this is your place. Ours was a winter stay so we took water activities off the table, but the setting is ideal and the house is so well appointed that even our teenagers enjoyed themselves. The kitchen was very well-equipped which is a major plus in remote locations. We found everything we needed to prepare meals. We also enjoyed making s'mores over the fire pit. We took a trip to visit the dam which we all enjoyed. Would...
GREAT RATES! Beautiful views on Lake Hartwell!!!!

New 3 Bdr Home - Clemson / Pendleton - Close to Everything

10.0 out of 10, Exceptional, (6)
"Wonderful home! "
New 3 Bdr Home - Clemson / Pendleton - Close to Everything

Peaceful Six Mile Vacation Home w/ Fire Pit

10.0 out of 10, Exceptional, (5)
"Great location, clean and quiet property, not a far drive to Big Rock for a day of climbing. Will definitely book again ."
Peaceful Six Mile Vacation Home w/ Fire Pit

Big, very private country house where everyone can finally get together 🤙🏼

10.0 out of 10, Exceptional, (31)
"We needed a place to meet together as a family over Christmas. This place met our needs perfectly. We had space, entertainment (hiking trail, pool table, air hockey), big TV. Kitchen was fantastic with 2 dishwashers and a big wall oven and gas stovetop. Plenty of seating, and space. All appliances worked as stated. Marc is the best! What a great host. No hesitation needed, just book it!"
The price is SAR 1,872
SAR 2,374 total
includes taxes & fees
19 Feb - 20 Feb
Big, very private country house where everyone can finally get together 🤙🏼

5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!

10.0 out of 10, Exceptional, (83)
"If you are looking for an awesome place to gather with family and/or friends, look no further. We gathered to celebrate our grand daughter’s graduation from Clemson. It was the perfect spot. A great space with lots to do and plenty of room to spread out. The younger adults played ping pong and darts. The kitchen is fully equipped with everything you could possibly need with a gorgeous table to enjoy meals together. The views are breath taking from the living area. I personally loved several...
The price is SAR 2,832
SAR 5,891 total
includes taxes & fees
17 Feb - 18 Feb
5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!

Luxurious & Spacious Lake Hartwell Home

10.0 out of 10, Exceptional, (146)
"Our stay by included 14 people coming from New Jersey for my daughter’s wedding. The house was well laid out. The ground level living space was perfect for all the kids (eight of them ages 16 -25), giving them separate space from the older adults. The master bedroom and bathroom were a wonderful size. The outdoor space is perfect, being the end of January we didn’t utilize it much but in the warmer weather we would have been out there all the time. The home was well stocked with bath towels,...
Luxurious & Spacious Lake Hartwell Home

Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!

9.8 out of 10, Exceptional, (42)
"Our son recently moved to Seneca. This was our first trip to visit him. This place was perfect for our family. There was an enough space to spread out and not be crowded. The dock and kayaks were enjoyed by our teen sons. The location was convenient and close to everything. We will definitely be staying here again. "
Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!

Cozy Pet Friendly Cottage, 2 story Deep Water Dock - bring your boat!

10.0 out of 10, Exceptional, (90)
"Very clean, well appointed cottage, with beautiful views! Communication with the host was excellent. Everything we needed for a long weekend getaway. We look forward to returning in the future for another stay!"
Cozy Pet Friendly Cottage, 2 story Deep Water Dock - bring your boat!

Country Apple Cottage

9.6 out of 10, Exceptional, (7)
"Perfect for a family getaway Kelsey was very helpful and responded right away! The vrbo was equipped with everything you could need close to plenty stores and things to do. Would recommend this for a family vacation!"
The price is SAR 334
SAR 662 total
includes taxes & fees
24 Feb - 25 Feb
Country Apple Cottage

Lake Hartwell Waterfront Getaway

9.0 out of 10, Wonderful, (2)
"Properties was good - not sure it was “excellent”. It was easy to find and parking was pretty good for our four vehicles. View of the lake was pretty. All beds were comfortable- except not sure about 3 twins since we didn’t use them. We didn’t realize they were down in the basement. Kids ended up sleeping on the sofas in the den because they were too scared to go down there away from everyone plus it was pretty chilly down there. The bathroom toilet down there clogged easily and didn’t flush...
Lake Hartwell Waterfront Getaway

Make memories at the lake!

10.0 out of 10, Exceptional, (108)
"We absolutely loved our time in this lovely place and hope to return. The owners were a delight to talk to and made everything smooth as could be! I can't recommend this home enough!"
Make memories at the lake!

Valley Echoes on Lake Hartwell!

2.0 star property
10.0 out of 10, Exceptional, (2)
"We rented this home for Thanksgiving week and we were very impressed with how thoughtful the host was. They even supplied a turkey roasting pan for us. The beds were so comfortable with hi-end linens and pillows. We brought our boat and dogs and the property was so nice. A huge yard on the water with a nice pier to dock your boat or hang out on the water."
Valley Echoes on Lake Hartwell!

Spacious 8-bedroom house with WiFi and AC on peaceful Lake Keowee private cove.

9.6 out of 10, Exceptional, (5)
"Worked out good for our group "
Spacious 8-bedroom house with WiFi and AC on peaceful Lake Keowee private cove.

Lakefront Home, 6BR/4BA, Open Water/Dock. Sleeps 18. Boat Rental.

10.0 out of 10, Exceptional, (115)
"Fabulous place for large families!"
Lakefront Home, 6BR/4BA, Open Water/Dock. Sleeps 18. Boat Rental.

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

9.8 out of 10, Exceptional, (134)
"The property was clean, loaded with everything you need, and gave our large group room for privacy along with lots of time together around the beautiful dining table, the fire pit, and the pool table. Awesome stay and the host was wonderful to work with. Beautiful lake views as well!!"
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

Lakefront Keowee home with an oversized private dock, boat ramp and fire pit.

9.8 out of 10, Exceptional, (16)
"The property is as advertised. The house and yard are large, and the dock is outstanding."
Lakefront Keowee home with an oversized private dock, boat ramp and fire pit.

Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water

9.8 out of 10, Exceptional, (142)
"Great property, really secluded and right on the lake. The road coming in makes you feel like you're in a slasher movie but other than that, the place was nice and clean. Recommend."
Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water

Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath

10.0 out of 10, Exceptional, (58)
"This was the perfect place for our family trip. The house was beautiful and my nieces loved the game room!"
Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Seneca

Perfect Lake Hartwell Getaway - Gorgeous Lake Views!

10.0 out of 10, Exceptional, (80)
"We loved celebrating Christmas at this wonderful house. Three generations enjoyed the huge kitchen and multiple comfortable gathering spaces. Can’t wait to come back!"
Perfect Lake Hartwell Getaway - Gorgeous Lake Views!

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

9.2 out of 10, Wonderful, (74)
"Our stay was around when Helene Hurricane came through, Sept 27, 2024. The power was out so the cleaning person wasn't able to finish their task prior to our check in. However, there were clean linens and towels in the basement next to the washing machine. We also had trash bags, clean dishes and running water but no power. The cabin was nicely located in Seneca which wasn't far from the university. The cabin was also easy to find. "
Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Postcard Cabins Lake Hartwell

2.0 star property
10.0 out of 10, Exceptional, (2)
"Super cute, and comfy! A bit hard to drive up the hill with a car, but it was worth the quiet surroundings. Make sure to bring your own campfire stuff because they do charge extras. It has a full kitchen with plates and pans to cook if you want along with a mini fridge. "
The price is SAR 253
SAR 278 total
includes taxes & fees
3 Mar - 4 Mar
Postcard Cabins Lake Hartwell
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.