Photo by Cindy Keese
Search Vacation Homes in Seneca
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Next weekend
In two weeks
In one month
In two months
Compare 715 Vacation Homes in Seneca with updated reviews, rates, and availability.

Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath
Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath
10.0 out of 10, Exceptional, (62)

Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
9.6 out of 10, Exceptional, (160)

The Brick House At Currahee
The Brick House At Currahee
9.6 out of 10, Exceptional, (52)
The price is SAR 398
SAR 753 total
includes taxes & fees
24 Mar - 25 Mar

Great weekend getaway just a mile from downtown!
Great weekend getaway just a mile from downtown!
10.0 out of 10, Exceptional, (9)

Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson
Lake Hartwell House - Sunsets & Deep Water Dock - Close to Clemson & Anderson
10.0 out of 10, Exceptional, (76)

Serenity Bay, Keowee Lakefront Cabin, Covered Dock, Kayaks, Clean, Near Clemson
Serenity Bay, Keowee Lakefront Cabin, Covered Dock, Kayaks, Clean, Near Clemson
10.0 out of 10, Exceptional, (197)

4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
9.8 out of 10, Exceptional, (343)

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
9.8 out of 10, Exceptional, (134)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Other property types in Seneca

Postcard Cabins Lake Hartwell
Postcard Cabins Lake Hartwell
10.0 out of 10, Exceptional, (3)
The price is SAR 338
SAR 371 total
includes taxes & fees
3 Apr - 4 Apr

Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
9.6 out of 10, Exceptional, (160)

4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
9.8 out of 10, Exceptional, (343)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Seneca hotels
Recent reviews of Seneca hotels

Lakeside Lodge Clemson
5/5 Excellent
" Thx"
A verified traveler stayed at Lakeside Lodge Clemson
Posted 2 days ago