Photo by Cindy Keese

Find Luxury Hotels in Seneca, SC

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Compare Seneca Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Quality Inn Seneca US-123

2.5 star property
8.0 out of 10, Very Good, (557)
"Very good stay! The front desk service is fantastic!"
The price is SAR 331
SAR 402 total
includes taxes & fees
19 Jan - 20 January 2025
Quality Inn Seneca US-123
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Seneca

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Seneca?
Expedia can help you get a flight to Greenville-Spartanburg Intl. Airport (GSP) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to get what you want to make your stay special. If you want an upscale hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Seneca offers. While you’re visiting, you might want to think about enjoying the sporting events and university, which Seneca is known for.
How many luxury hotels are there in Seneca?
Lie in the lap of luxury during your getaway to Seneca in one of Expedia’s 5 luxury hotels.
When can I expect good weather in Seneca?
Planning for the weather is an important factor for making your trip to Seneca a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.
What's there to see and do in Seneca?
Enjoy all that Seneca has to offer and visit Blue Ridge Field, Keowee Reservoir, and Lake Keowee. If you have extra time while you’re in the area, you might want to see Keowee Key Golf Course and Lake Hartwell.